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  药店国别: 美国药房
产地国家: 美国
所属类别: 皮肤科药物->抗真菌类药物
处方药:处方药
包装规格: 100毫克/毫升 2毫升/小瓶 25小瓶/盒
计价单位:
  点击放大  
生产厂家英文名:
Mylan
该药品相关信息网址1:
https://www.rxlist.com/consumer_thiamine_vitamin_b1/drugs-condition.htm
原产地英文商品名:
THIAMINE 100mg/mL 2mL/vial 25vials/box
原产地英文药品名:
thiamine hydrochloride
中文参考商品译名:
硫胺素 100毫克/毫升 2毫升/小瓶 25小瓶/盒
中文参考药品译名:
盐酸硫胺素
原产地国家批准上市年份:
0000/00/00
英文适应病症1:
thiamine deficiency
英文适应病症2:
beriberi
临床试验期:
完成
中文适应病症参考翻译1:
硫胺素缺乏
中文适应病症参考翻译2:
脚气病
药品信息:

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详细处方信息以本药内容附件PDF文件(20194921402726.pdf)的“原文Priscribing Information”为准
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部分中文硫胺素处方资料(仅供参考)


【英文名称】
THIAMINE


【中文名称】
硫胺素

【适用证】

盐酸硫胺素注射液可有效治疗硫胺素缺乏或脚气病,无论是干燥(与神经系统有关的主要症状)还是潮湿(与心血管系统有关的主要症状)品种。盐酸硫胺素注射应该用于需要快速恢复硫胺素的地方,如韦尼克脑病,急性塌陷的婴儿脚气病,硫胺素缺乏导致的心血管疾病,或呕吐严重时的妊娠神经炎。当给予具有边缘硫胺素状态的个体的IV葡萄糖以避免心力衰竭的沉淀时,也表明了这一点。

盐酸硫胺素注射液也适用于已确定硫胺素缺乏的患者,由于共存的严重厌食,恶心,呕吐或吸收不良,不能口服硫胺素。盐酸硫胺素注射剂通常不适用于口服摄入减少或胃肠道吸收减少的情况,因为通常应给予多种维生素。

【用法用量】

患有心肌衰竭的“湿”脚气病必须作为紧急心脏病治疗,在这种情况下,必须通过IV途径缓慢给予硫胺素(见警告)。

在脚气病的治疗中,每天3次给予10mg至20mg盐酸硫胺素,持续长达2周。 (参见关于重复注射硫胺素的警告。)建议每天服用含有5毫克至10毫克硫胺素的口服多种维生素制剂,每日服用一个月,以达到身体组织饱和度。

温和的婴儿脚气病可能对口服治疗有反应,但如果发生塌陷,可以小心静脉注射25 mg剂量。

应纠正不良饮食习惯,并应规定丰富均衡的饮食摄入量。

妊娠神经炎患者,如果呕吐严重到足以排除足够的口服治疗,应每天服用5 mg至10 mg盐酸硫胺素IM。

在Wernicke-Korsakoff综合征的治疗中,盐酸硫胺素以100mg的初始剂量静脉内给药,然后每天给予IM剂量50mg至100mg,直至患者饮食定期均衡饮食。 (参见关于重复注射硫胺素的警告。)

给予葡萄糖的具有边缘硫胺素状态的患者应在最初的几升静脉输液中接受100mg盐酸硫胺素,以避免引起心力衰竭。

当溶液和容器允许时,应在给药前目视检查肠外药物产品中的颗粒物质和变色。

【注意事项】

对硫胺素或该药物中的任何成分敏感的病史是禁忌症。 (有关详细信息,请参阅警告。)

【INDICATIONS AND USAGE】

Thiamine hydrochloride injection is effective for the treatment of thiamine deficiency or beriberi whether of the dry (major symptoms related to the nervous system) or wet (major symptoms related to the cardiovascular system) variety. Thiamine hydrochloride injection should be used where rapid restoration of thiamine is necessary, as in Wernicke's encephalopathy, infantile beriberi with acute collapse, cardiovascular disease due to thiamine deficiency, or neuritis of pregnancy if vomiting is severe. It is also indicated when giving IV dextrose to individuals with marginal thiamine status to avoid precipitation of heart failure.

Thiamine hydrochloride injection is also indicated in patients with established thiamine deficiency who cannot take thiamine orally due to coexisting severe anorexia, nausea, vomiting, or malabsorption. Thiamine hydrochloride injection is not usually indicated for conditions of decreased oral intake or decreased gastrointestinal absorption, because multiple vitamins should usually be given.

【CONTRAINDICATIONS】

A history of sensitivity to thiamine or to any of the ingredients in this drug is a contraindication. (See WARNINGS for further information.)

【DOSAGE AND ADMINISTRATION】

"Wet" beriberi with myocardial failure must be treated as an emergency cardiac condition, and thiamine must be administered slowly by the IV route in this situation (see WARNINGS).

In the treatment of beriberi, 10 mg to 20 mg of thiamine hydrochloride are given IM 3 times daily for as long as 2 weeks. (See WARNINGS regarding repeated injection of thiamine.) An oral therapeutic multivitamin preparation containing 5 mg to 10 mg thiamine, administered daily for one month, is recommended to achieve body tissue saturation.

Infantile beriberi that is mild may respond to oral therapy, but if collapse occurs, doses of 25 mg may cautiously be given IV.

Poor dietary habits should be corrected and an abundant and well-balanced dietary intake should be prescribed.

Patients with neuritis of pregnancy in whom vomiting is severe enough to preclude adequate oral therapy should receive 5 mg to 10 mg of thiamine hydrochloride IM daily.

In the treatment of Wernicke-Korsakoff syndrome, thiamine hydrochloride has been administered IV in an initial dose of 100 mg, followed by IM doses of 50 mg to 100 mg daily until the patient is consuming a regular, balanced diet. (See WARNINGS regarding repeated injections of thiamine.)

Patients with marginal thiamine status to whom dextrose is being administered should receive 100 mg thiamine hydrochloride in each of the first few liters of IV fluid to avoid precipitating heart failure.

Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit.

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详细处方信息以本药内容附件PDF文件(20194921402726.pdf)的“原文Priscribing Information”为准
---------------------------------------------------------------

更新日期:  2019-4-9
附件:
20194921402726.pdf    

 
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