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 详细处方信息以本药内容附件PDF文件（201111617461110.pdf）的“原文Priscribing Information”为准
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部分中文DisperMox处方资料（仅供参考）

Ranbaxy Pharmaceuticals 宣布在全美为呼吸道疾病的高发季节及时推出 DisperMox(TM)
    Ranbaxy Laboratories Limited (RLL) 旗下全资子公司 Ranbaxy Pharmaceuticals Inc (RPI) 将在2003年11月4日于新奥尔良召开的美国儿科学会 (American Academy of Pediatrics, AAP) 全美会展上正式推出 DisperMox(TM)（阿莫西林 (Amoxicillin) 口服悬浮液片剂，200毫克与4 00毫克）。Ranbaxy 最先开发出阿莫西林散剂，这种散剂被用作口服悬浮液的另一种选择，它服用方便且药量精确。DisperMox(TM) 片剂一旦与水混合便立即消散，它以悬浮液的形式服用。
    DisperMox(TM) 包含一种新剂型阿莫西林，这种新剂型旨在提高 Amoxil( R)（阿莫西林口服悬浮液粉末）强大的药效、安全性和耐药性。DisperMox(TM) 具有较可口的草莓口味，药量精确，一天服用两次。由于 DisperMox(TM) 属于片剂，因此不需要冷藏。
    负责品牌营销的副总裁 Jeffrey Thomas 表示：“作为15年以来美国发展最迅速的制药公司，DisperMox 的推出是 Ranbaxy 在向品牌化制药领域发展的过程中迈出的重要而又令人振奋的又一步。伴随全球呼吸道疾病高发季节的即将来临，我们认为，医生和病人将会发现这种创新的阿莫西林剂型更便于服用，而且药量精确且效力强大。”
    最近，悬浮液或液剂的推出越来越被公认为是在儿童服药问题上取得的最大进步，尤其是对于那些5岁以下（以及患了病的更大一些的儿童）无法或不愿吞咽药片或胶囊的患儿。那些低龄儿童的父母都熟知给其不合作的孩子喂药是多大的挑战，而且他们中的很多人还曾遇到过冷藏时间过久导致阿莫西林药剂感染细菌的情况。作为一种方便的选择，DisperMox 口服悬浮液片剂可与水混合服用，溶于水后可形成口感不错的液体。
    非处方专利药室 (Office of Generic Drugs, OGD) 已经测定，Ranbaxy 的配方预计可产生与 Amoxil（阿莫西林口服悬浮液）相同的疗效。该机构将 Amo xil 作为安全性和效力的参照基准。通过致力于阿莫西林悬浮液市场，该新药将成为抗生素药物市场上一种具有竞争力的药物，据估计，其在美国市场的销售将超过 1.057亿美元（IMS：2003年4月）。
    这种新型阿莫西林药剂将特别有益于那些易受到链球菌属 (Streptococcu s spp.)（仅限于α和β溶血性菌株）、肺炎链球菌 (streptococcus pneumoniae )、葡萄球菌属 (Staphylococcus spp.) （仅限于β-内酰胺酶阴性菌株）、或流感嗜血菌 (H. influenzae) 等菌株感染的细菌性传染病（包括急性中耳炎 (Acut e Otitis Media, AOM)（细菌性耳部感染））患儿。中耳炎是美国儿童去看儿科的最普遍的原因（2001年看诊人数超过3500万），这就意味着它是儿童中最常见的细菌性传染病。它是美国医疗保健系统相当大的负担，因为它，美国医疗保健系统每年要增加50亿美元以上的费用开支。
    为了再次研究中耳炎（细菌性耳部感染）抗菌药物治疗的最佳方法，美国疾病控制与预防中心 (CDC) 于1996年成立了抗药性肺炎链球菌治疗工作小组 (D rug-Resistant Streptococcus pneumoniae Therapeutic Working Group)。根据出版的文献、监督数据以及专家的临床经验，全体工作人员推荐阿莫西林作为中耳炎的首选治疗药物。结合阿莫西林的药效、安全性、较少的不良反应以及相当低的成本，CDC 工作小组总结认为，口服阿莫西林仍是对中耳炎患儿经验治疗的最佳首选药物。
    在今天发布的一份单独声明中，RPI 透露，Novartis Pharmaceuticals 的全美客户营销、经济发展和战略联盟部门的前任副总裁 Jeffrey Thomas 已加入 Ranbaxy，成为其品牌营销部门的副总裁。Thomas 先生将负责 Ranbaxy 在北美市场的专有的医药业务。

印度制药厂商获准在美国销售学名药
    据海外媒体报道，印度大型制药厂商兰巴克西公司生产的一种学名药日前获得美国食品和药物管理局的批准在美上市。
    该公司称，获准在美国销售的是治疗小儿细菌感染的抗生素DisperMox。这种抗生素与英国葛兰素史克公司的药物Amoxil同类，都为阿莫西林，用于治疗小儿窦炎，扁桃腺炎等传染性疾病。
　　据兰巴克西公司称，该公司将瞄准的美国1亿多美元这一市场，葛兰素史克公司的Amoxil一直在这一市场中占统治地位。该公司说，美国食品和药物管理局（FDA）已批准今年10月开始在美国零售该公司的DisperMox。
　　葛兰素史克公司说，Amoxil的专利很久前就已到期，兰巴克西公司将与其它学名药竞争，而不是葛兰素史克公司。
　　兰巴克公司发言人拒绝透露DisperMox的售价。他说，价格要在药品投放市场之前才能决定，但要比Amoxil的售价低很多。

GENERIC NAME: AMOXICILLIN TABLETS - FOR ORAL SUSPENSION (ah-mox-ih-SILL-in)

BRAND NAME(S): DisperMox

USES: Amoxicillin is a penicillin-type antibiotic that is used to treat a wide variety of bacterial infections.

HOW TO USE: Take this medication with or without food, usually every 12 hours, or as directed by the doctor. Do not chew or swallow the tablets whole. Place the prescribed dose in a glass with 2 teaspoonfuls of water and stir until thoroughly mixed. Drink all of the liquid immediately after mixing. Then rinse the glass with a small amount of water and drink the contents. This will insure the whole dose is taken. Do not mix the tablet with any liquid other than water. Antibiotics work best when the amount of medicine in your body is kept at a constant level. Therefore, take this drug at evenly spaced intervals. Continue to take this medication until the full prescribed amount is finished even if symptoms disappear after a few days. Stopping the medication too early may allow bacteria to continue to grow, which may result in a relapse of the infection. Inform the doctor if your condition persists or worsens.

SIDE EFFECTS: Nausea, vomiting or diarrhea may occur. If any of these effects persist or worsen, notify the doctor or pharmacist promptly. This medicine may cause temporary staining of the teeth. Proper brushing will usually remove any staining and may prevent it from occurring. Tell the doctor immediately if any of these highly unlikely but very serious side effects occur: dark urine, persistent nausea or vomiting, stomach/abdominal pain, yellowing eyes or skin, easy bruising or bleeding, persistent sore throat or fever. This medication may rarely cause a severe intestinal condition (pseudomembranous colitis) due to a resistant bacteria. This condition may occur weeks after treatment has stopped. Do not use anti-diarrhea products or narcotic pain medications if you have the following symptoms because these products may make them worse. Tell the doctor immediately if you develop: persistent diarrhea, abdominal or stomach pain/cramping, or blood/mucus in your stool. Use of this medication for prolonged or repeated periods may result in oral thrush or a new vaginal yeast infection (oral or vaginal fungal infection). Contact the doctor if you notice white patches in your mouth, a change in vaginal discharge or other new symptoms. A serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include: rash, itching, swelling, dizziness, trouble breathing. If you notice other effects not listed above, contact the doctor or pharmacist.

PRECAUTIONS: Before taking amoxicillin, tell your doctor or pharmacist if you are allergic to it; or to penicillin or cephalosporin antibiotics; or if you have any other allergies. Before using this medication, tell the doctor or pharmacist your medical history, especially of: kidney disease, other infections (e.g., mononucleosis). This medicine may contain aspartame. If you have phenylketonuria (PKU) or any other condition where you must restrict your intake of aspartame (or phenylalanine), consult the doctor or pharmacist regarding the safe use of this medicine. This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor. This drug passes into breast milk. Consult your doctor before breast-feeding.

DRUG INTERACTIONS: Before using this medication, tell the doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: allopurinol, live vaccines, methotrexate, probenecid. This medication may decrease the effectiveness of combination-type birth control pills. This can result in pregnancy. You may need to use an additional form of reliable birth control while using this medication. Consult your doctor or pharmacist for details. Amoxicillin may cause false positive results with certain diabetic urine testing products (cupric sulfate-type). This drug may also affect the results of certain lab tests. Make sure laboratory personnel and the doctors know you use this drug. Do not start or stop any medicine without doctor or pharmacist approval.

OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. Symptoms of overdose may include: severe vomiting, persistent diarrhea, a severe decrease in the amount of urine or seizures.

NOTES: Do not share this medication with others. This medication has been prescribed for your current condition only. Do not use it later for another infection unless told to do so by the doctor. A different medication may be necessary in those cases. With prolonged treatment, laboratory and/or medical tests (e.g., kidney and liver function, complete blood counts) should be performed periodically to monitor your progress or check for side effects. Consult the doctor for more details.

MISSED DOSE: If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

STORAGE: Store at room temperature between 68-77 degrees F (20-25 degrees C) away from light and moisture. Do not store in the bathroom. Keep all medicines away from children and pets.

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 详细处方信息以本药内容附件PDF文件（201111617461110.pdf）的“原文Priscribing Information”为准
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