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 详细处方信息以本药内容附件PDF文件（201092223320833.pdf）的“原文Priscribing Information”为准
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部分中文DIPROLENE处方资料（仅供参考）

英文药名: Diprolene (Betamethasone Dipropionate)
中文药名: 二丙酸倍氯米松

药品名称
药品名称: 倍氯美松双丙酸酯, 倍氯松, 氯倍他美松二丙酸酯, 倍氯米松, 丙酸倍氯米松，二丙酸倍氯米松，丙酸倍氯松，丙酸倍氯美松.
英文名: Beclomethasone, Becotide, Aldecin, Beclazone, Diprolene.

适应症
1.系强效外用糖皮质激素类药，具有抗炎、抗过敏和止痒等作用，能抑制支气管渗出物，消除支气管粘膜肿胀，解除支气管痉挛。对皮肤血管收缩作用远比氢化可的松强。局部抗炎作用是肤轻松和去炎松的５倍。亲脂性较强，易渗透，涂于患处３０分钟后即生效。
2.对体暖和排尿也无明显影响。因此，局部外用不会抑制人体皮质功能和因皮质功能紊乱所引起的不良反应。
3.外用可治疗各种炎症皮肤病，如湿疹、过敏性皮炎、神经性皮炎、接触性皮炎、牛皮癣、瘙痒等。气雾剂可用于慢性及过敏性哮喘、过敏性鼻炎等。

用法用量
1. 露, 露或软膏：每日涂患处２～３次，必要时包扎之。
2. 气雾剂：成人一般每次喷药０．０５～０．１ｍｇ（每揿１次约喷出主药０．０５～０．０７ｍｇ），１日３～４次。
严重病例用全身性皮质激素控制症状后再用本品治疗，每日最大量不超过１ｍｇ。儿童用量按年龄酌减，每日最大量不超过０．８ｍｇ。待症状缓解后逐渐减量。
任何疑问，请遵医嘱！

注重事项
1.气雾剂只用于慢性哮喘，急性发作时宜应用较大剂量水溶性皮质激素，或用支气管扩张剂和抗组胺类药，待症状控制后再改用本品气雾剂治疗。
2.使用本品后，应在哮喘控制良好的情况下逐渐停用口服皮质激素，一般在本气雾剂治疗４～５日后才慢慢减量停用。
3.气雾剂对别病人有刺激感，咽喉部出现白色念珠菌感染，但吸后立即漱口可减轻刺激感，并可用局部抗真菌药控制感染。
4.本品乳膏不宜长期密封给药，因易引起红斑、丘疹、痂皮等，此时应减少用药量。不宜用于皮肤结核、疱疹、水痘、皮肤化脓性感染、溃疡、Ⅱ度以上烫伤、冻伤和湿疹性外耳道炎等。本品不能用于眼科，对孕妇及婴儿需慎用。

规格
露, 露或软膏 0.05%

GENERIC NAME: betamethasone dipropionate

BRAND NAME: Diprolene; Diprolene AF; (Diprosone and Alphatrex have been discontinued)

DRUG CLASS AND MECHANISM: Betamethasone is a synthetic (man-made) corticosteroid that is used topically (on the skin). Betamethasone mimics the action of cortisol (hydrocortisone), the naturally-occurring steroid produced in the body by the adrenal glands. Corticosteroids have potent anti-inflammatory actions and also suppress the immune response. Corticosteroids have many effects on the body, but they most often are used for their potent anti-inflammatory effects, particularly in those conditions in which the immune system plays an important role. The FDA approved betamethasone in July 1983.

PRESCRIPTION: Yes

GENERIC AVAILABLE: Yes

PREPARATIONS: Cream, ointment, lotion: 0.05%

STORAGE: All preparations should be kept between 15 and 30 C (59-86 F). Lotion should be shaken before each use.

PRESCRIBED FOR: Betamethasone is used for the relief of itching and inflammation associated with a wide variety of skin conditions in patients 13 years of age or older. Examples include allergic dermatitis, atopic dermatitis, contact dermatitis, and plaque psoriasis.

DOSING:
A thin strip of betamethasone cream or ointment is applied gently to the affected area once or twice daily.
A few drops of the lotion is applied to the affected area once or twice daily.
The lotion should be massaged gently until it disappears.

Large doses and prolonged use of betamethasone may cause large amounts to be absorbed into the body and suppress production of cortisol by the adrenal glands. Therefore, the lotion should not be used for longer than two weeks, and not more than 50 ml should be used per week. The augmented cream or ointment should be limited to 45 grams per week. Betamethasone should not be used with occlusive dressings because occlusive dressings increase absorption into the body.

DRUG INTERACTIONS: Combining topical steroids with topical anthralin may increase psoriasis symptoms. Therefore, topical steroids should be discontinued 1 week before starting anthralins.

PREGNANCY: Use of betamethasone in pregnant women has not been studied. When corticosteroids are given systemically (orally, intramuscularly or intravenously) to pregnant animals fetal abnormalities occur.

NURSING MOTHERS: It is not known if betamethasone is secreted in breast milk. Corticosteroids absorbed into the body may appear in breast milk and may cause harmful effects in breast fed infants.

SIDE EFFECTS: The most commonly-noted side effects of betamethasone are burning at the area of application, itching, irritation, and dryness.

Topical application of corticosteroids may suppress the body's production of cortisol. If suppression has occurred for a long enough period of time, discontinuing the potent corticosteroid can be associated with symptoms of cortisol deficiency. (It takes the adrenal glands some time before they can begin producing cortisol again.) Absorption of potent corticosteroids can increase the glucose concentration in the blood (especially worrisome in people with diabetes) and cause symptoms of steroid excess (weight gain, redistribution of fat stores, and psychiatric problems). The suppression of inflammation and the immune response caused by steroid excess also allows infections to occur more easily.

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 详细处方信息以本药内容附件PDF文件（201092223320833.pdf）的“原文Priscribing Information”为准
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2010年9月23日更新