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 详细处方信息以本药内容附件PDF文件（20109823533918.pdf）的“原文Priscribing Information”为准
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部分中文GAMANIL处方资料（仅供参考）

【中文品名】洛非帕明

【药效类别】抗抑郁药>米帕明类

【通用药名】LOFEPRAMINE

【别　　名】Amplit, Deftan-70, Deprimil, Emdalen, Gamanil, Gamonil, Lopramine, Timelit, Tymelyt

【化学名称】Ethanone, 1-(4-chlorophenyl)-2-[[3-(10,11-dihydro-5H-dibenz[b,f]azepin-5-yl)propyl]methylamino]-

【用　　途】三环类抗抑郁药

GAMANIL
Drug class Description :
Tricyclic antidepressants (TCADs) .

Generic Name :
Lofepramine

Drug description :
Maroon f-c scored tablet.

Presentation :
Tablets, lofepramine (as hydrochloride) 70 mg .

Indications :
Symptoms of depressive illness.

Adult Dosage :
One twice a day or one three times a day.

Child Dosage :
Not recommended. Not recommended.

Contra Indications :
Acute myocardial infarction, heart block, disorders of cardiac rhythm, coronary insufficiency, severe liver disease, mania. Pregnancy and lactation.

Special Precautions :
Cardiovascular disease, liver disorders, hyperthyroidism, tumours of adrenal medulla, epilepsy, diabetes, glaucoma, urinary retention, constipation, renal disease. Monitor cardiac and hepatic function during long term therapy. Psychoses, patients with suicidal tendencies. Reduce doses for the elderly.

Interactions :
With or within 14 days of MAOIs. Carbamazepine, phenytoin, neuroleptics. Barbiturates, other antidepressants, alcohol, anticholinergics, local anaesthetics containing adrenaline (epinephrine) or noradrenaline (norepinephrine), cimetidine, oestrogens, quinidine, antihypertensives.

Adverse Reactions :
Anticholinergic effects such as dry mouth, constipation, urinary retention, blurred vision and changes in accommodation, palpitations and tachycardia. Tinnitus, drowsiness, nervousness or insomnia. Tremor, orthostatic hypotension, dizziness, sweating, weakness and fatigue, ataxia, epileptiform seizures, occasional extrapyramidal symptoms and gastric irritation.

Weight loss or gain. Allergic skin reactions, jaundice and blood disorders (test blood regularly). Conduction defects and cardiac arrhythmias. Endocrine effects such as changes in libido, impotence, gynaecomastia and galactorrhoea. Changes in blood sugar concentrations. Some patients may switch over into mania and schizophrenic symptoms activated, especially in the elderly. Withdrawal symptoms.

Manufacturer :
Merck

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 详细处方信息以本药内容附件PDF文件（20109823533918.pdf）的“原文Priscribing Information”为准
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2010-9-9更新