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部分中文Dermovate处方资料（仅供参考）
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药品名称
    通用名称：氯倍他索、丙酸氯倍米松、丙酸氯倍他索、氯倍米松、氯氟甲泼尼松、氯氟米松、特美肤
    英文名：ClobetasolSN-201, Temovate, Temovate/application, Clobesol, Clobetasol Propionate, Clobetasolum, Dermadex, Dermoval, Dermovate, Dermoxin, Dermoxinale
    商品名称: 倍氯他索丙酸酯, 特美夫, 特美肤, 恩肤, 蒽肤

药理作用　　
    为肾上腺皮质激素类药物，具有较强的抗炎、抗瘙痒和血管收缩作用，抗炎作用约为氢化可的松的112倍。与皮肤渗透促进剂月桂氮卓酮等配成软膏。
适应症　　
    可用于治疗皮肤炎症和瘙痒症，如神经性皮炎、接触性皮炎、脂溢性皮炎、湿疹、局限性瘙痒症、盘状红斑狼疮等．

用法用量　　
    外用,软膏涂敷,一日2-3次,病情好转后改为一日1次。或遵医嘱！

禁用/慎用　
    孕妇,儿童,面部,腋窝及腹股沟处慎用。

不良反应　
    可有局部烧灼感,搔痒。出现局部刺激应立即停药。大面积涂擦可致全身反应。

How does it work?
Dermovate cream and Dermovate ointment both contain the active ingredient clobetasol propionate, which is a type of medicine called a topical corticosteroid.

Corticosteroids are medicines used for reducing inflammation. Inflammation of the skin happens due to irritation of the skin, and is caused by the release of various substances that are important in the immune system. These substances cause blood vessels to widen, resulting in the irritated area becoming red, swollen, itchy and painful.

When clobetasol is applied to the skin it works by acting inside the skin cells to decrease the release of these inflammatory substances. This reduces swelling, redness and itch. Clobetasol is a very potent corticosteroid that is applied to the skin to treat severe inflammatory skin disorders, such as eczema and psoriasis, that have not responded to milder steroids.

Dermovate ointment is more greasy than the cream. It is more suitable for very dry, scaly areas of skin, whereas moist or weepy skin is best treated with the cream.

Dermovate cream or ointment should be applied thinly to the affected areas of skin once or twice a day to start with. As soon as the condition starts to improve, you should use it less frequently, as directed by your doctor. Dermovate should not be used for longer than four weeks at a time. If your skin condition has not improved after two to four weeks of treatment you should consult your doctor. Repeat courses maybe necessary to control flare-ups of your skin condition, but should only be started on the advice of your doctor.

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What is it used for?
Dermovate cream and ointment are used in short courses to treat severe inflammatory skin disorders, such as those listed below, when milder corticosteroids have not been effective.
Eczema.
Psoriasis.
Skin disorder called lichen planus, in which there are patches on the skin that appear as flat-topped, shiny, almost violet itchy areas.
Skin disorder called discoid lupus erythematosus, which is caused by the immune system attacking the skin.

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Warning!
Dermovate cream and ointment are for external use on the skin only.
The cream or ointment should be applied thinly and evenly to the affected area(s). Click here to see how much to use.

Avoid getting the medicine in the eyes, or in contact with the inside of the mouth or nose. Rinse with cold water if accidental contact occurs.

Wash your hands thoroughly after applying this medicine, unless the hands are the area being treated.
If your doctor has advised you to use dressings with this medicine, the skin should be cleansed before applying the cream/ointment under a fresh dressing.

If corticosteroids are used long-term, on large areas of skin, raw or broken skin, skin folds, or under airtight dressings they are absorbed into the body more. This increases the risk of local side effects such as skin thinning, and those on other parts of the body, such as a decrease in the production of natural hormones by the adrenal glands. For this reason, continuous, long-term use of this medicine should be avoided wherever possible, particularly in children and on large areas of skin. You should only use airtight dressings over the affected area if instructed by your doctor. If there is no improvement in your skin after two to four weeks of treatment you should consult your doctor.

If this medicine is used on the face, wherever possible it should not be used for longer than five days. You should not use airtight dressings to cover the area treated.

If used in children, wherever possible this medicine should not be used for longer than five days, or on the face. You should not use airtight dressings to cover the area treated. Be aware that children's nappies can also act as an airtight dressing and can increase the absorption of the medicine. Children being treated with this medicine should be reviewed by the doctor at least once a week.

If you have been prescribed this medicine to treat psoriasis you should have regular check-ups with your doctor. This is because although corticosteroids may be useful for psoriasis in the short-term, they can sometimes make psoriasis worse, and may cause the condition to relapse into generalised pustular psoriasis after the treatment is stopped.

If you think the area of skin you are treating has become infected you should stop using this medicine and consult your doctor.

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Use with caution in
Children.
Psoriasis.

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Not to be used in
Children less than one year of age.
Skin infected with viruses (eg cold sores, genital herpes, chickenpox, shingles), fungi (eg thrush, ringworm, athlete's foot) or bacteria (eg impetigo).
Acne vulgaris.
Chronic inflammatory disorder of the facial skin (acne rosacea).
Inflammatory rash around the mouth (perioral dermatitis).
Itching around the back passage and genitals.
Widespread plaque psoriasis.

This medicine should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy.If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately.

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Pregnancy and breastfeeding
Certain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, before using any medicine.

This medicine should not be used during pregnancy unless considered essential by your doctor. If it is prescribed by your doctor it should not be used on large areas of skin, underneath airtight dressings, or for prolonged periods of time. Consult your doctor for further information.

This medicine should not be used during breastfeeding unless considered essential by your doctor. If it is prescribed by your doctor it should not be used on large areas of skin, underneath airtight dressings or for prolonged periods of time. If it is applied to the breasts it should be washed off carefully before breastfeeding and then reapplied afterwards.

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Label warnings
This medication is to be spread thinly and sparingly on the skin.

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Side effects
Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Just because a side effect is stated here does not mean that all people using this medicine will experience that or any side effect.

Skin irritation at site of application, such as burning, itching and redness.
Allergic inflammation of the skin (contact dermatitis).
Thinning of the skin.
Changes in skin pigmentation.
Stretch marks (striae).
Groupings of fine blood vessels becoming prominent under the skin (telangiectasia).
Excessive hair growth (hypertrichosis).

The side effects listed above may not include all of the side effects reported by the medicine's manufacturer.For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.

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How can this medicine affect other medicines?
This medicine is not known to affect other medicines. However, as with all medicines, it is important to tell your doctor or pharmacist what medicines you are already using, including those bought without a prescription and herbal medicines, before you start treatment with this medicine. Similarly, check with your doctor or pharmacist before using any new medicines while using this one, to ensure that the combination is safe.

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于2010年4月12日更新