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详细处方信息以本药内容附件PDF文件（2020102823560623.pdf）的原文为准
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部分中文LANOXIN处方资料（仅供参考）

【成份】本品主要成份为：地高辛

【性状】本品为无色或几乎无色的澄明液体。

【适应症】（1）用于急性和慢性心功能不全。（2）用于控制伴有快速心室率的心房颤动、心房扑动患者的心室率及室上性心动过速。

【规格】2ml∶0.5mg

【用法用量】成人常用量静脉注射：0.25－0.5㎎，用5%葡萄糖注射液稀释后缓慢注射，以后可用0.25㎎，每隔4－6小时按需注射，但每日总量不超过1㎎；不能口服者需静脉注射，维持量，0.125－0.5㎎，每日－次。小儿常用量静脉注射：按下列剂量分3次或每6－8小时给予。早产新生儿按体重0.015－0.025㎎/㎏；足月新生儿按体重0.02－0.03㎎/㎏；1月－2岁按体重0.04－0.05㎎/㎏；2－5岁按体重0.025－0.035㎎/㎏；5－10岁按体重0.015－0.03㎎/㎏；10岁或10岁以上照成人常用量。

【不良反应】（1）常见的不良反应包括：促心律失常、胃纳不佳或恶心、呕吐（刺激延髓中枢）、下腹痛、异常的无力、软弱。（2）少见的反应包括：视力模糊或"色视"（如黄视、绿视）、腹泻、中枢神经系统反应如精神抑郁或错乱。（3）罕见的反应包括：嗜睡、头痛及皮疹、寻麻疹（过敏反应）。（4）在洋地黄的中毒表现中，促心律失常最重要，最常见者为室性早搏，约占促心律失常不良反应的33%。其次为房室传导阻滞，阵发性或加速性交界性心动过速，阵发性房性心动过速伴房室传导阻滞，室性心动过速、窦性停搏、心室颤动等。儿童中心律失常比其他反应多见，但室性心律失常比成人少见。新生儿可有P－R间期延长。

【禁忌】①与钙注射剂合用；②任何强心甙制剂中毒；③室性心动过速、心室颤动；④梗阻性肥厚型心肌病（若伴收缩功能不全或心房颤动仍可考虑）；⑤预激综合征伴心房颤动或扑动。

【注意事项】（1）不宜与酸、碱类配伍。（2）慎用：①低钾血症；②不完全性房室传导阻滞；③高钙血症；④甲状腺功能低下；⑤缺血性心脏病；⑥急性心肌梗死早期；⑦活动心肌炎；⑧肾功能损害。（3）用药期间应注意随访检查：①血压、心率及心律；②心电图；③心功能监测；④电解质尤其钾、钙、镁；⑤肾功能；⑥疑有洋地黄中毒时，应作地高辛血药浓度测定。过量时，由于蓄积性小，－般于停药后1－2天中毒表现可以消退。（4）应用时应注意监测地高辛血药浓度；（5）应用时应注意剂量个体化。

Drug Name: LANOXIN(digoxin) Injection
Company: Covis Pharma

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What is digoxin?
Lanoxin (digoxin) is derived from the leaves of a digitalis plant. Digoxin helps make the heart beat stronger and with a more regular rhythm. Lanoxin is used to treat heart failure. Lanoxin is also used to treat atrial fibrillation, a heart rhythm disorder of the atria (the upper chambers of the heart that allow blood to flow into the heart).

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Important Information
You should not use Lanoxin if you have ventricular fibrillation (a heart rhythm disorder of the ventricles, or lower chambers of the heart that allow blood to flow out of the heart).

Before taking this medicine：You should not use Lanoxin if you are allergic to digoxin, or if you have ventricular fibrillation (a heart rhythm disorder of the ventricles, or lower chambers of the heart that allow blood to flow out of the heart).

To make sure Lanoxin is safe for you, tell your doctor if you have ever had:

a serious heart condition such as "sick sinus syndrome" or "AV block" (unless you have a pacemaker);

a heart attack;

slow heartbeats that have caused you to faint;

Wolff-Parkinson-White Syndrome (sudden fast heartbeats);

kidney disease;

an electrolyte imbalance (such as low levels of calcium, potassium, or magnesium in your blood);

a thyroid disorder; or

if you have recently been sick with vomiting or diarrhea.

Tell your doctor if you are pregnant. It is not known whether digoxin will harm an unborn baby. However, having heart failure or atrial fibrillation during pregnancy may cause complications such as premature birth or low birth weight, or risk of death in both mother and baby. The benefit of treating heart problems with digoxin may outweigh any risks to the baby.

It may not be safe to breast-feed while using Lanoxin. Ask your doctor about any risk.

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How should I use Lanoxin?

Take Lanoxin exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.

Try to take oral Lanoxin at the same time every day.

Measure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).

Take Lanoxin regularly even if you feel fine or have no symptoms. Get your prescription refilled before you run out of medicine completely.

Lanoxin injection is given as a shot into a muscle, or as an infusion into a vein. A healthcare provider will give you this injection if you are unable to take the medicine by mouth.

Your blood pressure and heart rate will need to be checked daily.

You may need frequent blood tests. Your kidney function may also need to be checked.

You should not stop taking Lanoxin suddenly. Stopping suddenly may make your condition worse.

Store at room temperature away from moisture and heat.

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What happens if I miss a dose?
ake the medicine as soon as you can, but skip the missed dose if your next dose is due in less than 12 hours. Do not take two doses at one time.

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What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of digoxin can be fatal.

Overdose symptoms may include nausea, vomiting, loss of appetite, and feeling tired.

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What should I avoid while using Lanoxin?

Avoid becoming overheated or dehydrated during exercise, in hot weather, or by not drinking enough fluids. Digoxin overdose can occur more easily if you are dehydrated.

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Lanoxin side effects

Get emergency medical help if you have signs of an allergic reaction to Lanoxin: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

nausea, vomiting, diarrhea, stomach pain;

fast, slow, or uneven heart rate;

a light-headed feeling, like you might pass out;

bloody or black, tarry stools;

confusion, weakness, hallucinations, unusual thoughts or behavior;

breast swelling or tenderness;

blurred vision, yellowed vision; or

(in babies or children) stomach pain, weight loss, growth delay, behavior changes.

Serious side effects may be more likely in older adults and those who are ill or debilitated.

Common Lanoxin side effects may include:

nausea, diarrhea;

feeling weak or dizzy;

headache, weakness, anxiety, depression; or

rash.

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What other drugs will affect Lanoxin?

Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.

Many drugs can interact with digoxin. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.

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详细处方信息以本药内容附件PDF文件（2020102823560623.pdf）的原文为准
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