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  药店国别: 英国药房
产地国家: 英国
所属类别: 作用于消化系统药物->便秘
处方药:处方药
包装规格: 290微克/28粒/盒
计价单位:
  点击放大  
生产厂家英文名:
Allergan Pharmaceuticals International Limited UK
该药品相关信息网址1:
https://www.medicines.org.uk/emc/product/2041/pil
原产地英文商品名:
Constella hard capsules 290μg/28Grain/box
原产地英文药品名:
linaclotide
中文参考商品译名:
恒星硬胶囊 290微克/28粒/盒
中文参考药品译名:
利那洛肽
原产地国家批准上市年份:
0000/00/00
英文适应病症1:
It is used to treat the symptoms of moderate to severe irritable bowel syndrome (often just called “IBS”) with constipation in adult patients
临床试验期:
完成
中文适应病症参考翻译1:
治疗成年患者便秘中度至重度肠易激综合症(通常简称为“ IBS”)的症状
药品信息:

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 详细处方信息以本药内容附件PDF文件(201910117521333.pdf)的“原文Priscribing Information”为准
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 部分中文恒星硬胶囊处方资料(仅供参考)


【英文名称】
Constella hard capsules

【适用证】

康士坦含有活性物质利那洛肽。 它用于治疗成年患者便秘中度至重度肠易激综合症(通常简称为“ IBS”)的症状。

IBS是一种常见的肠道疾病。 IBS伴便秘的主要症状包括:

---胃痛或腹痛,

---感觉肿胀,

---不常见的,坚硬的,小的或颗粒状的粪便(粪便)。

这些症状可能因人而异。

Constella的工作原理

Constella在您的肠道内局部起作用,可帮助您减轻疼痛,减少腹胀,并恢复肠道的正常功能。 它不会被人体吸收,而是会附着在肠道表面称为鸟苷酸环化酶C的受体上。 通过附着在该受体上,它可以阻止疼痛感,并允许液体从体内进入肠道,从而使粪便松弛并增加肠蠕动。

【用法用量】

始终严格按照医生的指示服用该药。 如果不确定,请咨询您的医生或药剂师。

建议剂量为每天一次口服一粒胶囊(即290微克利那洛肽)。 饭前至少30分钟服用胶囊。

如果治疗4周后您的症状未见改善,则应联系医生。
 

【警告和注意事项】

您的医生在排除了其他疾病(尤其是肠胃疾病)并认定您患有IBS便秘后,才给您服用该药。由于这些其他疾病可能具有与IBS相同的症状,因此必须立即向医生报告症状的任何变化或不规则性,这一点很重要。

如果您腹泻严重或持续时间很长(频繁流水的大便经过7天或更长时间),请停止服用Constella并联系医生(请参阅第4节)。确保您喝大量的液体来补充水和电解质,例如腹泻中丢失的钾。

如果您肠或直肠出血,请与您的医生交谈。

如果您的年龄超过65岁,请特别小心,因为腹泻的风险更高。

如果您患有严重或长时间的腹泻以及其他疾病,例如高血压,先前的心脏和血管疾病(例如先前的心脏病发作)或糖尿病,也应格外小心。

如果您患有克罗恩氏病或溃疡性结肠炎等肠道发炎性疾病,请与您的医生取得联系,因为在这些患者中不建议使用Consstella。
 

【服用Constella之前您需要了解的内容】

不要服用Constella

---如果您对利那洛肽或本药的任何其他成分过敏(在第6节中列出)。

---如果您或您的医生知道您的胃或肠阻塞。
 

【What Constella is used for】

Constella contains the active substance linaclotide. It is used to treat the symptoms of moderate to severe irritable bowel syndrome (often just called “IBS”) with constipation in adult patients.

IBS is a common gut disorder. The main symptoms of IBS with constipation include:

---stomach or abdominal pain,

---feeling bloated,

---infrequent, hard, small or pellet-like stools (faeces).

These symptoms may vary from person to person.

How Constella works

Constella acts locally in your gut, helping you to feel less pain and less bloated, and to restore the normal functioning of your bowels. It is not absorbed into the body, but attaches to receptor called guanylate cyclase C on the surface of your gut. By attaching to this receptor, it blocks the sensation of pain and allows liquid to enter from the body into the gut, thereby loosening the stools and increasing your bowel movements.
 

【How to take Constella 】

Always take this medicine exactly as your doctor has told you. Check with your doctor or pharmacist if you are not sure.

The recommended dose is one capsule (i.e. 290 micrograms of linaclotide) taken orally once a day. The capsule should be taken at least 30 minutes before a meal.

If you have not experienced improvement in your symptoms after 4 weeks of treatment, you should contact your doctor.
 

【What you need to know before you take Constella】

Do not take Constella

---if you are allergic to linaclotide or any of the other ingredients of this medicine (listed in section 6).

---if you or your doctor know that you have a blockage in your stomach or bowels.
 

【Warnings and precautions】

Your doctor has given this medicine to you after excluding other diseases, especially of your bowels and concluding that you suffer from IBS with constipation. Because these other diseases may have the same symptoms as IBS, it is important that you report any change or irregularity in symptoms to your doctor promptly.

If you experience severe or prolonged diarrhoea (passing of frequent watery stools for 7 days or more), stop taking Constella and contact your doctor (see section 4). Make sure you drink plenty of fluids to replace the water and electrolytes like potassium lost from the diarrhoea.

Talk to your doctor if you experience bleeding from the bowel or rectum.

Take special care if you are older than 65 years, as there is a higher risk you experience diarrhoea.

Take also special care if you have severe or prolonged diarrhoea and an additional disease, such as high blood pressure, previous disease of the heart and blood vessels (e.g. such as previous heart attacks) or diabetes.

Talk to your doctor if you suffer from inflammatory diseases of the guts such as Crohn’s disease or ulcerative colitis as Constella is not recommended in these patients.
 

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 详细处方信息以本药内容附件PDF文件(201910117521333.pdf)的“原文Priscribing Information”为准
---------------------------------------------------------------

更新日期: 2019-9-19
附件:
201910117521333.pdf    

 
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