---------------------------------------------------------------
详细处方信息以本药内容附件PDF文件（201951420165340.pdf）的“原文Priscribing Information”为准
---------------------------------------------------------------
部分中文Gastrografin Lemon solution处方资料（仅供参考）

【英文名称】Gastrografin Lemon solution

【适用证】

Gastrografin（泛影葡胺和泛影酸钠溶液）适用于胃肠道（食道，胃，近端小肠和结肠）节段的放射照相检查。 当不粘溶的更粘稠的试剂如硫酸钡不可行或具有潜在危险时，特别指出该制剂。

胃窦炎也可用作躯干计算机断层扫描（身体成像）中对比度增强的辅助手段; 当未增强成像可能无法提供足够的定义来区分肠道正常环与邻近器官或疑似病理区域时，指示制剂与静脉注射不透射线造影剂一起使用

【用法用量】

一般

该培养基不适用于制备肠胃外给药的溶液。仅口服或直肠给药。在程序之后，取消任何未使用的部分。

用于钡研究的常规预备措施也适用于该药剂。

对于儿科和严重恶病质的患者，建议维持静脉输液管路。

胃肠道节段的放射学检查 口服给药：成人口服剂量可以为30至90 mL（碘至11至33 g），具体取决于检查的性质和患者的体型。对于婴儿和5岁以下的儿童，30毫升（11克碘）通常是足够的;对于5至10岁的儿童，建议剂量为60 mL（22 g碘）。如果需要，这些儿科剂量可以用水，碳酸饮料，牛奶或矿物油1：1稀释。当用于婴儿时，可以在奶瓶中给予溶液。小儿剂量也可用于脱水和/或衰弱的成年患者。当造影剂用于老年恶病质个体时，也推荐1：1稀释。

对于非常年轻（10公斤以下）和虚弱的儿童，应稀释剂量：建议使用1份Gastrografin（泛影葡胺和泛影葡胺钠溶液）3份水。

对于灌肠或肠造口灌注：当用于灌肠和肠造口灌注时，应稀释胃泌素。当用作灌肠剂时，建议的成人稀释液是在1,000 mL自来水中的240 mL（88 g碘）。对于5岁以下的儿童，建议在自来水中稀释1：5;对于5岁以上的儿童，在500 mL自来水中90 mL（33 g碘）是合适的稀释度。

断层扫描（身体成像）

通常的成人剂量是240mL稀释的胃泌素溶液，通过用自来水稀释25mL（9.17g碘）至1升制备。当指示时，可以使用较少稀释的溶液[最多77mL（28.26g碘）用自来水稀释至1升]。在成像前约15至30分钟口服给药剂量，以使造影剂到达骨盆环。

【禁忌】

不要对已知对Gastrografin或其任何成分过敏的患者给药

【特殊警告和使用注意事项】

在使用异丙托溴铵后，观察到荨麻疹，血管神经性水肿，皮疹，支气管痉挛，口咽水肿和过敏反应的过敏反应。

在患有窄角型青光眼或易感性或预先存在的排尿障碍（例如前列腺增生或膀胱出口梗阻）的患者中使用抗胆碱能药时应谨慎行事。

由于患有囊性纤维化的患者可能易患胃肠动力障碍，因此在这些患者中应谨慎使用异丙托溴铵和其他抗胆碱能药物。

【INDICATIONS AND USAGE】

Gastrografin (Diatrizoate Meglumine and Diatrizoate Sodium Solution) is indicated for radiographic examination of segments of the gastrointestinal tract (esophagus, stomach, proximal small intestine, and colon). The preparation is particularly indicated when a more viscous agent such as barium sulfate, which is not water-soluble, is not feasible or is potentially dangerous.

Gastrografin may also be used as an adjunct to contrast enhancement in computed tomography of the torso (body imaging); the preparation is indicated, in conjunction with intravenous administration of a radiopaque contrast agent, when unenhanced imaging may not provide sufficient definition in distinguishing normal loops of bowel from adjacent organs or areas of suspected pathology

【CONTRAINDICATIONS】

Do not administer to patients with a known hypersensitivity to Gastrografin or any of its components

【DOSAGE AND ADMINISTRATION】

General

This medium is not to be us ed for the preparation of solutions for parenteral administration. Oral or rectal administration only. Dis card any unus ed portion after procedure.

The routine preparatory measures employed for barium studies are also appropriate for this agent.

For pediatric and severely cachectic patients the maintenance of an intravenous fluid line may be advisable.

Radiographic Examination of Segments of the Gastrointestinal Tract

Oral Administration: Adult oral dosage may range from 30 to 90 mL (11 to 33 g iodine), depending on the nature of the examination and the size of the patient. For infants and children less than 5 years of age, 30 mL (11 g iodine) are usually adequate; for children 5 to 10 years of age, the suggested dose is 60 mL (22 g iodine). These pediatric doses may be diluted 1:1, if desired, with water, carbonated beverage, milk, or mineral oil. When used in infants, the solution may be given in a nursing bottle. Pediatric doses may also be used in dehydrated and/or debilitated adult patients. A 1:1 dilution is also recommended when the contrast medium is used in elderly cachectic individuals.

For very young (under 10 kg) and debilitated children the dose should be diluted: 1 part Gastrografin (Diatrizoate Meglumine and Diatrizoate Sodium Solution) in 3 parts water is recommended.

For Enemas or Enterostomy Instillations: Gastrografin should be diluted when it is used for enemas and enterostomy instillations. When used as an enema, the suggested dilution for adults is 240 mL (88 g iodine) in 1,000 mL of tap water. For children under 5 years of age, a 1:5 dilution in tap water is suggested; for children over 5 years of age, 90 mL (33 g iodine) in 500 mL of tap water is a suitable dilution.

Tomography (Body Imaging)

A usual adult dose is 240 mL of a dilute Gastrografin solution prepared by diluting 25 mL (9.17 g iodine) to one liter with tap water. Less dilute solutions [up to 77 mL (28.26 g iodine) diluted to one liter with tap water] may be used when indicated. The dose is administered orally about 15 to 30 minutes prior to imaging in order to permit the contrast medium to reach the pelvic loops.

【Besondere Warnhinweise und Vorsichtsmaßnahmen für die Anwendung】

Nach der Anwendung von Ipratropiumbromid wurden überempfi ndlichkeitsreaktionen in Form von Urtikaria, Angioödem, Ausschlag, Bronchospasmus, oropharyngealem Ödem und Anaphylaxie beobachtet.

Vorsicht ist geboten bei der Anwendung von Anticholinergika bei Patienten mit Engwinkelglaukom bzw. entsprechender Prädisposition oder mit vorbestehender Miktionsstörung (z. B. bei Prostatahyperplasie oder Blasenauslassobstruktion).

Da Patienten mit zystischer Fibrose zu gastrointestinalen Motilitätsstörungen neigen können, ist Ipratropiumbromid, wie auch andere Anticholinergika, bei diesen Patienten mit Vorsicht anzuwenden.

---------------------------------------------------------------
详细处方信息以本药内容附件PDF文件（201951420165340.pdf）的“原文Priscribing Information”为准
---------------------------------------------------------------