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详细处方信息以本药内容附件PDF文件（201941521464733.pdf）的“原文Priscribing Information”为准
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部分中文SIMPLICEF处方资料（仅供参考）

【英文名称】SIMPLICEF

【适用证】

SIMPLICEF片剂用于治疗由中间金黄色葡萄球菌，金黄色葡萄球菌，犬链球菌（G组，β溶血性），大肠杆菌，多杀巴斯德氏菌和奇异变形杆菌的敏感菌株引起的狗皮肤感染（伤口和脓肿）。

【用法用量】

剂量范围

SIMPLICEF（头孢泊肟酯）片剂的剂量范围为5-10mg / kg（2.3-4.5mg / lb）体重，口服给药，每天一次。 剂量可以在有或没有食物的情况下给予。 确定任何特定患者的剂量必须考虑诸如感染的严重程度和性质，致病微生物的易感性以及患者宿主防御机制的完整性等因素。 获取用于培养和培养的致病生物样本 在开始抗菌治疗之前进行灵敏度测试。 一旦获得结果，继续进行适当的治疗。

持续时间

SIMPLICEF片剂应每日一次，连续5-7天或临床症状停止后2-3天，最多28天。 如果没有看到治疗反应，治疗急性感染不应持续3-4天以上。

【禁忌】

Cefpodoxime proxetil禁用于对头孢泊肟或β-内酰胺类（青霉素和头孢菌素类）抗生素过敏的狗。

【警告】

不适合人类使用。 将此药和所有药物放在儿童接触不到的地方。 抗菌药物，包括青霉素和头孢菌素，可引起致敏个体的过敏反应。 为了尽量减少过敏反应的可能性，建议那些处理此类抗微生物剂（包括头孢泊肟）的人避免产品与皮肤和粘膜直接接触。

【INDICATION】

SIMPLICEF tablets are indicated for the treatment of skin infections (wounds and abscesses) in dogs caused by susceptible strains of Staphylococcus intermedius, Staphylococcus aureus, Streptococcus canis (group G, β hemolytic), Escherichia coli, Pasteurella multocida, and Proteus mirabilis.

【DOSAGE AND ADMINISTRATIO】

Dose range

The dose range of SIMPLICEF (cefpodoxime proxetil) tablets is 5-10 mg/kg (2.3-4.5 mg/lb) body weight, administered orally, once a day. The dose may be given with or without food. The determination of dosage for any particular patient must take into consideration such factors as the severity and nature of the infection, the susceptibility of the causative organisms, and the integrity of the patient's host-defense mechanisms. Obtain a sample of the pathogenic organism for culture and sensitivity testing prior to beginning antimicrobial therapy. Once results become available, continue with appropriate therapy.

Duration

SIMPLICEF tablets should be administered once daily for 5-7 days or for 2-3 days beyond the cessation of clinical signs, up to a maximum of 28 days. Treatment of acute infections should not be continued for more than 3-4 days if no response to therapy is seen.

【CONTRAINDICATIONS】

Cefpodoxime proxetil is contraindicated in dogs with known allergy to cefpodoxime or to the β-lactam (penicillins and cephalosporins) group of antibiotics.

【WARNINGS】

Not for human use. Keep this and all drugs out of reach of children. Antimicrobial drugs, including penicillins and cephalosporins, can cause allergic reactions in sensitized individuals. To minimize the possibility of allergic reactions, those handling such antimicrobials, including cefpodoxime, are advised to avoid direct contact of the product with the skin and mucous membranes.

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详细处方信息以本药内容附件PDF文件（201941521464733.pdf）的“原文Priscribing Information”为准
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