【用法用量】
用法：
(1) 治疗过程包括2周期的诱导治疗，随后3周期的巩固治疗和4周期的持续治疗。
(2) 诱导或巩固治疗的单个周期包括连续静脉输注28天，随后14天间隔时间（共42天）。
(3) 维持治疗的单个周期包括连续静脉输注28天，随后56天间隔时间（共84天）。
- 建议第一疗程的前9天和第二疗程的前两天住院治疗。
- 用药前需用地塞米松预处理。
用量：
（1) 诱导治疗：≥45kg患者，在第一个疗程d1-7应予以9μg/d，d8-28予以28μg/d；后续的疗程则d1-28均为28μg/d；＜45kg患者，在第一个疗程d1-7应予以5 mcg/㎡/d，d8-28予以15mcg/㎡/d；后续的疗程则d1-28均为15mcg/㎡/d；
(2) 巩固治疗及维持治疗：≥45kg患者，d1-28均为28μg/d；＜45kg患者，d1-28均为15mcg/㎡/d。
- 使用静脉泵以保证恒定流速予以持续静脉输注治疗。
【What BLINCYTO is and what it is used for 】
The active ingredient in BLINCYTO is blinatumomab. This belongs to a group of medicines called antineoplastic agents which target cancer cells.
BLINCYTO is used to treat adults with acute lymphoblastic leukaemia. Acute lymphoblastic leukaemia is a cancer of the blood in which a particular kind of white blood cell called “B-lymphocyte” is growing out of control. This medicine works by enabling your immune system to attack and destroy these abnormal white blood cancer cells.
BLINCYTO is used to treat children (≥ 1 year old), teenagers and young adults with acute lymphoblastic leukaemia (ALL) when previous treatments have not worked or have stopped working.
【What you need to know before you use BLINCYTO】
Do not use BLINCYTO:
• if you are allergic to blinatumomab or any of the other ingredients of this medicine (listed in section 6).
•if you are breast-feeding.
【Children and adolescents 】
SBLINCYTO should not be used in children below 1 year of age.
【Other medicines and BLINCYTO 】
Tell your doctor, pharmacist or nurse if you are taking, have recently taken or might take any other medicines.
【Pregnancy and breast-feeding】
If you are pregnant, are breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or nurse for advice before taking this medicine.
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详细处方信息以本药内容附件PDF文件（201912219141611.pdf）的“原文Priscribing Information”为准
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