药品信息:
--------------------------------------------------------------- 详细处方信息以本药内容附件PDF文件(201911712524717.pdf)的“原文Priscribing Information”为准 --------------------------------------------------------------- 部分LONGRANGE 5%无菌溶液注射液处方资料(仅供参考)
【英文名称】LONGRANGE 5% STERILE SOLUTION INJECTION
【中文名称】LONGRANGE 5%无菌溶液注射液
【简介】
LONGRANGE(eprinomectin)是一种即用型无菌注射制剂,含有
eprinomectin,大环内酯类抗寄生虫的成员。 每毫升LONGRANGE在N-甲基-2-吡咯烷酮(30%v / v)和甘油三乙酸酯(qs)的共溶剂体系中含有50毫克的eprinomectin,以及50毫克的聚丙交酯 - 共 - 乙醇酸 75:25(PLGA),一种聚合物,可以从配方中缓慢释放eprinomectin,从而保持产品有效性的持续时间。 丁基化羟基甲苯(0.2 mg / mL)在配方中起抗氧化剂的作用。
依立诺克丁的化学名称是4“ - 脱氧-4” - 表异乙酰氨基 - 阿维菌素B. 它是阿维菌素化合物家族的半合成成员,由两种同源组分B和B的混合物组成,它们在C26中由一个亚甲基相互不同。
【适用证】
LONGRANGE以每110磅(50千克)体重1毫升的推荐剂量给药,可有效治疗和控制以下内部和外部寄生虫:
1.胃肠蛔虫
2.肺丝虫
LONGRANGE已经被证明可以有效地保护牛免受以下寄生虫的再感染,并在治疗后的指定时间内使用
【剂量和给药】
推荐剂量水平为每公斤体重1毫克依立诺克丁(每110磅体重1毫升)。
每毫升LONGRANGE含有50毫克的eprinomectin,足以治疗110磅(50千克)体重。 在两个注射部位之间分配大于10 mL的剂量,以减少偶尔的不适或部位反应。
【警告和预防措施】
用于人类消费的动物不得在最后一次治疗后48天内屠宰。
该药品未被批准用于20个月或更大的雌性奶牛,包括干奶牛。 在这些牛中使用可能导致牛奶和/或这些奶牛所生的牛犊中的药物残留。
预先反刍小牛的戒断期尚未确定。 小牛不要用于小牛肉加工。
【DESCRIPTION】
LONGRANGE (eprinomectin) is a ready-to-use, sterile injectable preparation containing eprinomectin, a member of the macrocyclic lactone class of antiparasitics. Each mL of LONGRANGE contains 50 mg of eprinomectin in a co-solvent system of N-methyl-2-pyrrolidone (30% v/v) and triacetin (qs), along with 50 mg of poly-lactide-co-glycolic-acid 75:25 (PLGA), a polymer that allows a slow release of eprinomectin from the formulation, thereby maintaining a prolonged duration of product effectiveness. Butylated hydroxytoluene (0.2 mg/mL) acts as an antioxidant in the formulation.
The chemical name of eprinomectin is 4"-deoxy-4" epiacetylamino-avermectin B . It is a semisynthetic member of the avermectin family of compounds consisting of a mixture of two homologous components, B and B , which differ by a single methylene group at C .
【INDICATIONS FOR USE】
LONGRANGE, when administered at the recommended dose volume of 1 mL per 110 lb (50 kg) body weight, is effective in the treatment and control of the following internal and external parasites of cattle:
【DOSAGE AND ADMINISTRATION】
LONGRANGE (eprinomectin) should be given only by subcutaneous injection in front of the shoulder at the recommended dosage level of 1 mg eprinomectin per kg body weight (1 mL per 110 lb body weight).
Each mL of LONGRANGE contains 50 mg of eprinomectin, sufficient to treat 110 lb (50 kg) body weight. Divide doses greater than 10 mL between two injection sites to reduce occasional discomfort
or site reaction.
--------------------------------------------------------------- 详细处方信息以本药内容附件PDF文件(201911712524717.pdf)的“原文Priscribing Information”为准 --------------------------------------------------------------- |