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  药店国别: 新西兰药房
产地国家: 欧洲共同体国家
所属类别: 作用于消化系统药物->胃溃疡
处方药:处方药
包装规格: 20毫克/胶囊 30胶囊/瓶
计价单位:
  点击放大  
生产厂家中文参考译名:
阿斯利康
生产厂家英文名:
ASTRAZENECA
该药品相关信息网址1:
https://www.medbroadcast.com/drug/getdrug/losec
该药品相关信息网址2:
https://www.drugs.com/uk/losec-20mg-capsules-leaflet.html
原产地英文商品名:
Losec 20mg/cap 30caps/bottle (Minimum order qty:20)
原产地英文药品名:
Omeprazole
中文参考商品译名:
洛赛克 20毫克/胶囊 30胶囊/瓶 (最低购买量:20)
中文参考药品译名:
奥美拉唑
原产地国家批准上市年份:
0000/00/00
英文适应病症1:
Peptic ulcer(Gastric and duodenal ulcer)
英文适应病症2:
Reflux esophagitis
英文适应病症3:
Zhuo - Ai's syndrome
临床试验期:
完成
中文适应病症参考翻译1:
消化性溃疡(胃、十二指肠溃疡)
中文适应病症参考翻译2:
反流性食管炎
中文适应病症参考翻译3:
卓-艾氏综合征
药品信息:

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 详细处方信息以本药内容附件PDF文件(20191714255632.pdf)的“原文Priscribing Information”为准
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部分中文Losec处方资料(仅供参考)

名称:洛赛克 Losec

药理作用:本品作用于胃腺壁细胞为H+-K+-ATP酶抑制剂,选择性对胃酸分泌有明显抑制作用,起效迅速。每日服用一次即能抑制胃酸分泌,作用可持续约24小时以上。

药代动力学:口服本品后,经小肠吸收,主要分布于胃肠道。血浆半衰期30~60分钟。通常单剂量生物利用度约35%,多剂量生物利用度增至约60%。主要在肝脏代谢。大约服用量的80%以代谢物的形式经尿排泄,其余从粪便排泄。

适应证:适用于消化性溃疡(胃、十二指肠溃疡)、反流性食管炎和卓-艾氏综合征(胃泌素瘤)。

用法与用量:十二指肠溃疡、胃溃疡和反流性食管炎:每日早晨吞服20mg,不可咀嚼,不可倾出内容物;对用其他治疗而不愈的患者,每日早晨吞服40mg。十二指肠溃疡疗程通常为2~4;胃溃疡和反流性食管炎疗程通常为4~8周。
卓-艾氏综合征:首次剂量为60mg,每晨一次;然后按不同病情调节每日剂量为20~120mg。其疗程视临床情况而定,但每日超过80mg时,应分为二次服用。

不良反应:本品耐受性好:曾有头痛、腹泻、便秘、腹痛、恶心或呕吐和腹胀等报道,偶见血清氨基转移酶(ALT,AST)增高、皮疹、眩晕、嗜睡、失眠等反应。上述反应与治疗本身的因果关系尚未确定。

注意事项:
1.当怀疑胃溃疡时,应首先排除癌症的可能性,因用本品治疗可减轻其症状,从而延误诊断。
2.虽然动物试验表明,本品无胎儿毒性或致畸作用,但对孕期妇女一般不用,对乳期妇女也应慎用。
3.尚无儿童用药经验。
4.肝肾功能不全者慎用。
5.本品可延缓经肝脏氧化代谢药物在体内的消除,如安定、苯妥英钠、华法令、硝苯地平。当本品和上述药物一起使用,应酌减后者的用量。

储藏:室温保存

DIN (Drug Identification Number)
02119579  LOSEC 10MG CAPSULE
02230737  LOSEC 10MG TABLET
00846503  LOSEC 20MG CAPSULE
02190915  LOSEC 20MG TABLET
02016788  LOSEC 40MG CAPSULE
02242461  LOSEC MUPS 10MG TABLET
02242462  LOSEC MUPS 20MG TABLET

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How does Losec work? What will it do for me?
Omeprazole belongs to the family of medications called proton pump inhibitors (PPIs). It slows or prevents the production of acid within the stomach. It is used to treat conditions where reduction in acid secretion is required for proper healing, including stomach and intestinal ulcers (gastric and duodenal ulcers), the prevention and treatment of ulcers associated with medications known as NSAIDs, reflux esophagitis, Zollinger-Ellison syndrome, heartburn, and gastroesophageal reflux disease (GERD). It is also used in combination with antibiotics to treat stomach ulcers caused by H. pylori bacteria.

Your doctor may have suggested this medication for conditions other than the ones listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.

Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.

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How should I use Losec?
The usual dose of omeprazole is 10 mg to 40 mg once daily, depending on the condition being treated. This medication can be taken with or without food.

When used to treat stomach ulcers caused by H. pylori in adults, the dose of omeprazole is 20 mg twice daily taken with amoxicillin 1,000 mg twice daily and clarithromycin 500 mg twice daily, all for 7 days. Another dosing regimen for H. pylori infections is omeprazole 20 mg, metronidazole 500 mg, and clarithromycin 250 mg, all twice daily for 7 days.

Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is important that this medication be taken exactly as prescribed by your doctor. If you miss a dose, take it as soon as possible and continue with your regular schedule. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

Store this medication at room temperature, protect it from light and moisture, and keep it out of the reach of children.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

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What form(s) does Losec come in?
Capsules
10 mg
Each opaque pink, delayed release capsule, printed in black, "10" on the body and "A O S" on the cap. contains 10 mg of omeprazole. Nonmedicinal ingredients: disodium hydrogen phosphate dihydrate, gelatin, hydroxypropyl cellulose, hydroxypropyl methylcellulose, iron oxide, lactose anhydrous, magnesium stearate, mannitol, methacrylic acid copolymer, microcrystalline cellulose, polyethylene glycol, sodium lauryl sulfate, and titanium dioxide.

20 mg
Each delayed release capsule with an opaque pink body, opaque reddish-brown cap, printed in black, "20" on the body and "A O M" on the cap contains 20 mg of omeprazole. Nonmedicinal ingredients: disodium hydrogen phosphate dihydrate, gelatin, hydroxypropyl cellulose, hydroxypropyl methylcellulose, iron oxide, lactose anhydrous, magnesium stearate, mannitol, methacrylic acid copolymer, microcrystalline cellulose, polyethylene glycol, sodium lauryl sulfate, and titanium dioxide.

40 mg
Each delayed release capsule with an opaque apricot body, opaque purple cap, printed in blue-black, "PRILOSEC 40" on the body and "MSD743" or "743" on the cap contains 40 mg of omeprazole. Nonmedicinal ingredients: cetyl alcohol, D&C Red No. 28, D&C Yellow No. 10, disodium hydrogen phosphate dihydrate, FD&C Blue No. 1, FD&C Red No. 40, gelatin, hydroxypropyl cellulose, hydroxypropyl methylcellulose, hydroxypropyl methylcellulose phthalate, lactose anhydrous, mannitol, microcrystalline cellulose, sodium lauryl sulfate, and titanium dioxide.

Tablets
10 mg
Each pink, round delayed-release tablet, printed "LOSEC 10" on both sides contains 10 mg of omeprazole. Nonmedicinal ingredients: hydroxypropyl methylcellulose, iron oxide, mannitol, methacrylic acid copolymer, microcrystalline cellulose, paraffin, polyethylene glycol, sodium starch glycolate, sodium stearyl fumarate, talc, and titanium dioxide.

20 mg
Each red-brown, round, delayed-release tablet, printed "LOSEC 20" on both sides contains 20 mg of omeprazole. Nonmedicinal ingredients: hydroxypropyl methylcellulose, iron oxide, mannitol, methacrylic acid copolymer, microcrystalline cellulose, paraffin, polyethylene glycol, sodium starch glycolate, sodium stearyl fumarate, talc, and titanium dioxide.

Some medications may have other generic brands available. Always ask your doctor or pharmacist about the safety of switching between brands of the same medication.

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Who should NOT take Losec?
Omeprazole should not be taken by anyone who is allergic to omeprazole or any of the ingredients of the medication.

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What side effects are possible with Losec?
Many medications can cause side effects. A side effect is an unwanted response to a medication when it is taken in normal doses. Side effects can be mild or severe, temporary or permanent. The side effects listed below are not experienced by everyone who takes this medication. If you are concerned about side effects, discuss the risks and benefits of this medication with your doctor.

The following side effects have been reported by at least 1% of people taking this medication. Many of these side effects can be managed, and some may go away on their own over time.

Contact your doctor if you experience these side effects and they are severe or bothersome. Your pharmacist may be able to advise you on managing side effects.
•abdominal or stomach pain
•constipation
•diarrhea or loose stools
•dizziness
•gas
•headache

Although most of the side effects listed below don't happen very often, they could lead to serious problems if you do not seek medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:
•bloody or cloudy urine
•changes in vision
•flu-like symptoms
•fever or chills
•infrequent or frequent urge to urinate
•mild skin rash or itching
•muscle aches or cramps
•pain or burning in the mouth or throat
•signs of liver damage (yellow skin or eyes, dark urine, loss of appetite, abdominal pain, fever, and fatigue)
•swelling of the hands or feet (if there is no shortness of breath)

Stop taking the medication and seek immediate medical attention if any of the following occur:
•redness, tenderness, itching, burning, or peeling of skin
•signs of an allergic reaction (such as difficulty breathing, hives, swelling of the face or throat)
•signs of bleeding (such as easy bruising, bleeding gums, nosebleeds, vomiting blood, blood in the urine, dark tarry stools)

Some people may experience side effects other than those listed. Check with your doctor if you notice any symptom that worries you while you are taking this medication.

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Are there any other precautions or warnings for Losec?
Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.

Liver disease: People with severe liver disease should generally not take more than 20 mg of omeprazole daily.

Severe stomach problems: If you have recurrent vomiting, difficulty swallowing, blood in the stool, coughing up of blood, or significant unintentional weight loss, check with your doctor immediately.

Pregnancy: This medication should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking this medication, call your doctor immediately.

Breast-feeding: It is not known if omeprazole passes into breast milk. If you are a breast-feeding mother and are taking this medication, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.

Children: The safety and effectiveness of using this medication have not been established for children.

Seniors: Using the same dosage, seniors reach higher blood levels of omeprazole than younger people. Therefore, seniors may need to take reduced doses and should generally not take more than 20 mg of omeprazole daily.

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What other drugs could interact with Losec?
There may be an interaction between omeprazole and any of the following:
•atazanavir
•cilostazol
•dasatinibfluvoxamine
•fluconazole
•gemfibrozil
•isoniazid
•itraconazole
•ketoconazole
•miconazole
•ticlopdine

If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
•stop taking one of the medications,
•change one of the medications to another,
•change how you are taking one or both of the medications, or
•leave everything as is.

An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.

Medications other than those listed above may interact with this medication. Tell your doctor or prescriber about all prescription, over-the-counter (non-prescription), and herbal medications you are taking. Also tell them about any supplements you take. Since caffeine, alcohol, the nicotine from cigarettes, or street drugs can affect the action of many medications, you should let your prescriber know if you use them.

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 详细处方信息以本药内容附件PDF文件(20191714255632.pdf)的“原文Priscribing Information”为准
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于2019年1月7日更新

更新日期: 2019-1-7
附件:
20191714255632.pdf    







 
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