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  药店国别: 英国药房
产地国家: 英国
所属类别: 皮肤科药物->皮肤炎症
处方药:处方药
包装规格: 0.1毫克/粒 100粒/瓶
计价单位:
  点击放大  
生产厂家中文参考译名:
百时美施贵宝
生产厂家英文名:
BRISTOL-MYERS SQUIBB PHARMA
该药品相关信息网址1:
http://www.bms.com/
原产地英文商品名:
FLORINEF TAB 0.1mg/tab 100tabs/bottle (Min order qty: 4)
原产地英文药品名:
FLUDROCORTISONE
中文参考商品译名:
富能片剂 0.1毫克/粒 100粒/瓶 (最低订货量:4)
中文参考药品译名:
氟氢可的松
原产地国家批准上市年份:
0000/00/00
英文适应病症1:
Atopic dermatitis
英文适应病症2:
Contact dermatitis
英文适应病症3:
Seborrheic dermatitis
英文适应病症4:
Eczema
英文适应病症5:
Adrenal insufficiency
临床试验期:
完成
中文适应病症参考翻译1:
过敏性皮炎
中文适应病症参考翻译2:
接触性皮炎
中文适应病症参考翻译3:
脂溢性皮炎
中文适应病症参考翻译4:
湿疹
中文适应病症参考翻译5:
肾上腺皮质功能减退
药品信息:

友情提示:该藥品需冷藏!

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 详细处方信息以本药内容附件PDF文件(201132018493215.pdf、201132018494033.pdf)的“原文Priscribing Information”为准
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部分中文氟氢可的松处方资料(仅供参考)

氟氢可的松片(Florinef,Fludrocortisone Tablets)
通用名称:氟氢可的松

英文名:Fludrocortisone

其它中文名:9-氟可的索醋酸酯、9α-氟氢可的松、醋酸氟氢可的松、氟氢可的松醋酸酯

其它英文名:Alfanonidrone、Florinef、Florinef Acetate、Fludrocortisone Acetate

药理作用  
有抗炎、抗过敏作用。能抑制结缔组织的增生,降低毛细血管和细胞膜的通透性,减少炎性渗出,抑制组胺及其他炎症递质的形成与释放,抗炎作用较氢化可的松强 15倍左右。
主要为盐皮质激素作用,虽有一定的糖皮质激素的活性,但常用剂量无明显糖皮质激素作用。

适应症  
用于过敏性皮炎、接触性皮炎、脂溢性皮炎、湿疹、神经性皮炎等皮肤病。
主要外用于过敏性皮炎、接触性皮炎、脂溢性皮炎、湿疹等皮肤病。也可用于肾上腺皮质功能减退症的辅助治疗。

用法用量  
成人口服,一日0.1-0.2mg, 分2次用.
成人常用量:
①阿狄森综合征,每日 0.1mg,与可的松或氢化可的松合用,如有高血压发生,减为每日 0.05mg;
②失盐型先天性肾上腺性综合征,每日 0.1~0.2mg,与可的松或氢化可的松合用。
或遵医嘱!
 
给药说明  
长期或大面积使用,可吸收引起全身性作用。面部长期使用,可发生皮肤变薄和毛细血管扩张。本品具较强的钠潴留作用,外用时偶见钠留及水肿。

禁用/慎用 
皮肤有化脓感染和真菌感染时禁用。

不良反应 
常见的不良反应为水肿、高血压、低血钾和心脏肥大,低血钾导致肌肉无力,必须补充KCl,如出现高血压则必须减少剂量。
 
规格
醋酸氟氢可的松片0.1mg

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Fludrocortisone acetate
英文商品名:Florinef   
                           
中文商品名:富能錠

醫師為何開此藥?
本藥為皮質類固醇,與您的腎上腺所分泌的荷爾蒙類似。它可緩解發炎的現象
(紅、腫、熱、痛),用來治療關節炎、嚴重過敏、氣喘及某些免疫失調的疾病
(皮膚、血液、甲狀腺、腎臟、眼睛、結腸炎等)。

如何使用此藥?
本藥須由醫師處方,非經醫師指示,不可擅自增減藥量或停藥。

使用此藥時該注意什麼?
服用類固醇會減弱您的抵抗力,若有類似感冒或感染症狀時,請儘速就醫。
長期服藥者,須定期抽血檢查、照X光、檢查眼睛,時常量血壓、身高、體重,及做身體檢查。
不要飲酒,並注意熱量攝取,以避免體重增加;體重增加異常時,請通知醫師。
併用止痛消炎藥或有胃腸潰瘍病史者,使用本類藥品需小心。
請將本劑連同藥袋放置於室溫之陰涼乾燥處避光儲存,請勿冷藏或冷凍。請勿放在孩童可以取得的場所。
服用此藥期間如需服用其它藥品時,請主動告訴您的醫師或藥師。

此藥品可能引起的副作用及處理方式:
若症狀持續數日或嚴重時,請停藥並立即就醫或與醫師連絡。
常見的副作用:食慾增加、消化不良、神經緊張、皮膚變色、頭昏、出汗、臉部發紅。
當您發生下列症狀時,請與您的醫師聯絡:噁心、嘔吐、胃有刺激感、體重急遽增加,臉、腳、關節、踝等部位發生腫脹,肌肉痛、虛弱,畏光、青春痘、皮膚變薄、毛髮增加、月經不正常。

忘記服藥時該怎麼辦:
若忘記服藥,則於想起時儘快服用;如果一天服藥超過兩次以上,若距離下次服藥時間少於4小時,則不需要補服,按原時間服用即可,切勿一次服用兩倍劑量。

懷孕或哺乳時該怎麼辦:
如果您準備懷孕或已懷孕,應告知並與您的醫師討論;不建議於授乳期間使用本品,最好能改用其它的乳製品以取代母乳。

Brand Name:Florinef

Generic Name:Fludrocortisone Acetate 0.1 mg Tab

Registration No.:HK-00036

Indications: Fludrocortisone Acetate is used to treat Addison's Disease (hypoadrenocorticism). May also be used to lower the potassium level in animals with high levels of potassium in their blood. Fludrocortisone is a mineralocorticoid, a hormone that helps to regulate the concentration of sodium and potassium in the body. For dogs and cats.

Caution: Corticosteroids may mask some signs of infection, and new infections may appear during their use. There may be decreased resistance and inability to localize infection when corticosteroids are used. If an infection occurs during fludrocortisone acetate therapy, it should be promptly controlled by suitable antimicrobial therapy. Prolonged use of corticosteroids may produce posterior subcapsular cataracts, glaucoma with possible damage to the optic nerves, and may enhance the establishment of secondary ocular infections due to fungi or viruses. Average and large doses of hydrocortisone or cortisone can cause elevation of blood pressure, salt and water retention, and increased excretion of potassium. These effects are less likely to occur with the synthetic derivatives except when used in large doses. However, since fludrocortisone acetate is a potent mineralocorticoid, both the dosage and salt intake should be carefully monitored in order to avoid the development of hypertension, edema, or weight gain. Periodic checking of serum electrolyte levels is advisable during prolonged therapy; dietary salt restriction and potassium supplementation may be necessary. All corticosteroids increase calcium excretion. Elderly pets may commonly have conditions that may be exacerbated by fludrocortisone therapy including, but not limited to, hypertension, edema, hypokalemia, congestive heart failure, cataracts, glaucoma, increased intraocular pressure, renal insufficiency, and osteoporisis. Elderly pets may also commonly be taking concomitant drug therapy such as digitalis glycosides, oral anticoagulants, antidiabetic drugs (oral agents and insulin), and aspirin which may interact with fludrocortisone. In general, dose selection for an elderly pet should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy. Pet that are lactating, pregnant or have seizure disorders should not be given Florinef. Should your pet experience the following side effects, contact your veterinarian for emegency medical attention: seizures, swelling of the mouth or tongue, hives, shortness of breath, infections that worsen. Store at room temperature.

Drug Interactions: When administered concurrently, the following drugs may interact with adrenal corticosteroids. Amphotericin B or potassium-depleting diuretics benzothiadiazines and related drugs, ethacrynic acid and furosemide)-enhanced hypokalemia. Check serum potassium levels at frequent intervals; use potassium supplements if necessary. Digitalis (digoxin) glycosides-enhanced possibility of arrhythmias or digitalis toxicity associated with hypokalemia. Monitor serum potassium levels; use potassium supplements if necessary. Oral anticoagulants-decreased prothrombin time response. Monitor prothrombin levels and adjust anticoagulant dosage accordingly. Antidiabetic drugs (oral agents and insulin)-diminished antidiabetic effect. Monitor for symptoms of hyperglycemia; adjust dosage of antidiabetic drug upward if necessary. Aspirin-increased ulcerogenic effect; decreased pharmacologic effect of aspirin. Salicylate (aspirin) toxicity may occur in patients who discontinue steroids after concurrent high-dose aspirin therapy. Monitor salicylate levels or the therapeutic effect for which aspirin is given; adjust salicylate dosage accordingly if effect is altered. Barbiturates, phenytoin, or rifampin-increased metabolic clearance of fludrocortisone acetate because of the induction of hepatic enzymes. Observe the pet for possible diminished effect of steroid and increase the steroid dosage accordingly. Anabolic steroids (particularly C-17 alkylated androgens such as oxymetholone, methandrostenolone, norethandrolone, and similar compounds)-enhanced tendency toward edema. Use caution when giving these drugs together, especially in patients with hepatic or cardiac disease. Vaccines-neurological complications and lack of antibody response. Estrogen-increased levels of corticosteroid-binding globulin, thereby increasing the bound (inactive) fraction; this effect is at least balanced by decreased metabolism of corticosteroids. When estrogen therapy is initiated, a reduction in corticosteroid dosage may be required, and increased amounts may be required when estrogen is terminated.

Side Effects: Most adverse reactions are caused by the drug's mineralocorticoid activity (retention of sodium and water) and include hypertension, edema, cardiac enlargement, congestive heart failure, potassium loss, and hypokalemic alkalosis. When fludrocortisone is used in the small dosages recommended, the glucocorticoid side effects often seen with cortisone and its derivatives are not usually a problem; however the following untoward effects should be kept in mind, particularly when fludrocortisone is used over a prolonged period of time or in conjunction with cortisone or a similar glucocorticoid. Musculoskeletal-muscle weakness, steroid myopathy, loss of muscle mass, osteoporosis, vertebral compression fractures, aseptic necrosis of femoral and humeral heads, pathologic fracture of long bones, and spontaneous fractures. Gastrointestinal-peptic ulcer with possible perforation and hemorrhage, pancreatitis, abdominal distention, and ulcerative esophagitis. Dermatologic-impaired wound healing, thin fragile skin, bruising, petechiae and ecchymoses, facial erythema, increased sweating, subcutaneous fat atrophy, purpura, striae, hyperpigmentation of the skin and nails, hirsutism, acneiform eruptions, and hives; reactions to skin tests may be suppressed. Neurological-convulsions, increased intracranial pressure with papilledema (pseudotumor cerebri) usually after treatment, vertigo, headache, and severe mental disturbances. Endocrine-menstrual irregularities; development of the cushingoid state; suppression of growth in children; secondary adrenocortical and pituitary unresponsiveness, particularly in times of stress (e.g., trauma, surgery, or illness); decreased carbohydrate tolerance; manifestations of latent diabetes mellitus; and increased requirements for insulin or oral hypoglycemic agents in diabetics. Ophthalmic-posterior subcapsular cataracts, increased intraocular pressure, glaucoma, and exophthalmos. Metabolic-hyperglycemia, glycosuria, and negative nitrogen balance due to protein catabolism. Allergic Reactions-allergic skin rash, maculopapular rash, and urticaria.

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 详细处方信息以本药内容附件PDF文件(201132018493215.pdf、201132018494033.pdf)的“原文Priscribing Information”为准
---------------------------------------------------------------

2011-3-21更新

更新日期: 2015-04-15
附件:


201132018494033.pdf    

201132018493215.pdf    

 
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