您好,欢迎光临世界标品! 登录 注册(订药物标准品请用邮件联系我们)

中国医药研发对照标品提供商
Non-clinical Research-used
Medicine Sample Provider

当前本网站药物产品种数共 8473 处方药 8099 非处方药 268 保健品/医疗用具 106

世界标品医药目录搜索(中英文):
世界各国官方药品目录搜索(英文):
世界标品医药知识搜索(中英文):

联系方式
国内客服电话:
国际免费电话:


QQ客服1:1793093587
QQ客服2:1586083059
QQ客服3:2786706041
QQ客服6:2992753224
QQ客服7:2394834588

咨询邮箱:
scimed.shanghai@shijiebiaopin.com
info@shijiebiaopin.com
pharmacy.shijiebiaopin1@gmail.com
pharmacy.shijiebiaopin2@gmail.com

  药店国别: 美国药房
产地国家: 美国
所属类别: 神经系统药物->神经肌肉松弛药物
处方药:处方药
包装规格: 4.63毫克/毫升 20毫克/毫升 1瓶
计价单位:
   
生产厂家中文参考译名:
ABBVIE INC
生产厂家英文名:
ABBVIE INC
该药品相关信息网址1:
https://www.duopa.com/
原产地英文商品名:
Duopa 4.63MG/ML; 20MG/ML 1 vial
原产地英文药品名:
CARBIDOPA; LEVODOPA
中文参考商品译名:
Duopa 4.63毫克/毫升 20毫克/毫升 1瓶
中文参考药品译名:
卡比多巴;左旋多巴
原产地国家批准上市年份:
0000/00/00
英文适应病症1:
Dystonia
临床试验期:
完成
中文适应病症参考翻译1:
肌张力障碍
药品信息:
卡比多巴/左旋多巴(有时称为levocarb)是卡比多巴和左旋多巴的组合,用于治疗帕金森氏病,[1]多巴胺响应性肌张力障碍(DRD),和关闭标签的致幻剂迁延性知觉障碍的治疗(HP​​PD )。它是根据几个品牌,包括息宁,Pharmacopa,Atamet和载脂蛋白Levocarb出售。根据英国批准的名称系统的通用名称是合作careldopa。 组合药物的益处 左旋多巴是经由一种称为多巴脱羧酶天然存在的酶的作用转化为多巴胺。这发生在两个外周循环和在左旋多巴后已越过血脑屏障的中枢神经系统。中枢多巴胺受体的激活提高帕金森氏病的症状;然而,活化周多巴胺受体引起恶心和呕吐。出于这个原因,左旋多巴通常组合施用与多巴脱羧酶抑制剂(DDCI),在此情况下卡比多巴,这是非常极性的(和充电在生理pH),并不能穿过血脑屏障,但是防止左旋多巴外围转化为多巴胺并由此降低了左旋多巴的不希望的边缘的副作用。使用卡比多巴也增加左旋多巴的量在血流中,可用于进入大脑。 Carbidopa/levodopa (sometimes referred to as levocarb) is the combination of carbidopa and levodopa and is used to treat Parkinson's disease,[1] dopamine-responsive dystonia (DRD), and off-label for the treatment of Hallucinogen Persisting Perception Disorder (HPPD). It is sold under several brand names, including Sinemet, Pharmacopa, Atamet, and Apo-Levocarb. The generic name under the British Approved Name system is Co-careldopa. Benefits of the combination drug Levodopa is converted to dopamine via the action of a naturally occurring enzyme called DOPA decarboxylase. This occurs both in the peripheral circulation and in the central nervous system after levodopa has crossed the blood brain barrier. Activation of central dopamine receptors improves the symptoms of Parkinson's disease; however, activation of peripheral dopamine receptors causes nausea and vomiting. For this reason levodopa is usually administered in combination with a DOPA decarboxylase inhibitor (DDCI), in this case carbidopa, which is very polar (and charged at physiologic pH) and cannot cross the blood brain barrier, however prevents peripheral conversion of levodopa to dopamine and thereby reduces the unwanted peripheral side effects of levodopa. Use of carbidopa also increases the quantity of levodopa in the bloodstream that is available to enter the brain.
更新日期: 2015-03-05
附件:
201532322503438.pdf    

 
调控比例: 100%
订购表单下载
Copyrights © 2010,2011,2012 www.ShiJieBiaoPin.com, Inc., All rights Reserved www.ShiJieBiaoPin.com, Inc.
客服工作时间:太平洋时间18:00-24:00
国内客服电话:     国际免费电话:
友情提示:以上电话为免费电话,无需您承担任何费用,世界标品提供中文客服,请您放心拨打!
电子邮箱:info.shijiebiaopin.com@gmail.com, info@shijiebiaopin.com