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  药店国别: 日本药房
产地国家: 日本
所属类别: 皮肤科药物->抗真菌类药物
处方药:处方药
包装规格: 10毫 10支
计价单位:
   
生产厂家英文名:
Pola
该药品相关信息网址1:
http://www.kegg.jp/medicus-bin/japic_med?japic_code=00061378
原产地英文商品名:
Lulicon 10g 10 tubes
原产地英文药品名:
Luliconazole
中文参考商品译名:
Lulicon 10毫 10支
中文参考药品译名:
卢立康唑
原产地国家批准上市年份:
0000/00/00
英文适应病症1:
ringworm
英文适应病症2:
tinea
英文适应病症3:
jock itch
临床试验期:
完成
中文适应病症参考翻译1:
脚癣
中文适应病症参考翻译2:
体癣
中文适应病症参考翻译3:
股癣
药品信息:
中文名称:卢立康唑 中文别名:4-(2,4-二氯苯基)-1,3-二硫戊环-2-叉-1-咪唑基乙腈 英文名称:Luliconazole 适应症 编辑 用于下列真菌感染:癣病--脚癣、体癣、股癣;念珠菌感染--指间糜烂症、擦烂;癜风 开发经过 卢立康唑是日本农药株式会社开发的咪唑类抗真菌药物,较早即开始非临床试验及乳膏的Ⅰ期临床试验、Ⅱ期临床试验第一阶段,其后由于战略原因停止了开发进程。90年代日本农药株式会社与Pola化工株式会社签署协议共同开发, Pola化工株式会社于2001开始乳膏的Ⅱ期临床试验第二阶段及Ⅲ期临床试验,并进行了洗剂的Ⅰ期临床试验及与乳膏的对比试验。最终本药于2005年6月获得批准,2005年7月20日起以商品名ルリコン (Lulicon)上市,乳膏及洗剂规格均为1%,用于下列真菌感染:癣病--脚癣、体癣、股癣;念珠菌感染—指间糜烂症、擦烂;癜风。 适应症特点 卢立康唑 卢立康唑 真菌性皮肤病是皮肤组织部位真菌感染的结果 。真菌感染部位可分布于全身皮肤,发病最高的为角质层,其典型代表病症为癣病、念珠菌感染及白癜风。调查显示,皮肤真菌感染患者占皮肤科门诊患者的13%左右,其中包括88.0%的癣病患者、8.5%的念珠菌感染患者和3.4%的白癜风患者,癣病中又有64.0%为足癣。 癣病是一种难治性皮肤疾病,病程缓慢,治疗复发率极高,发病时炎症明显,周边有水疱、脓胞、鳞屑及结痂等皮损现象,且伴有不同程度的瘙痒,严重影响人们的正常生活。癣病包括足癣、体癣、股癣等。足癣是皮肤癣菌侵犯跖趾间皮肤所引起的浅部真菌感染,俗称“脚气”。足癣很常见,世界各地均有,是真菌病中发病率最高的一种。在我国城市中成人发病率可达60%以上,不但可以传染自己,还可以传染他人,是产生手癣、体癣、股癣和甲癣的根源。体癣是发生在平滑皮肤上的浅层真菌感染。股癣是特指发生在腹股沟、会阴部和肛门周围的皮肤真菌感染。 念珠菌感染是由念珠菌属,尤其是白色念珠菌引起的一种真菌病。该病原菌既可侵犯皮肤和粘膜,又能累及内脏。最常见的皮肤念珠菌感染包括指间糜烂和擦烂。指间糜烂多见于长期浸泡于水中的作业人员,以3-4指间最为常见,指间皮肤浸渍发白,去除浸渍的皮肤,呈界限清楚的湿润面,基底潮红,可有少量渗液。擦烂是发生在皱折部位的皮肤急性炎症,表现为皮肤红斑、肿胀、潮湿、多汗、表皮浸渍,易有糜烂及浆液渗出,继发感染可形成微小脓疱及溃疡, 白癜风是后天因皮肤色素脱失而发生的局限性白色斑片,是一种常见病、多发病,为皮肤病中三大顽症之一。世界上各色人种、各种民族均可得病。全世界发病率约在1—2%左右。我国大约在2%左右。白癜风虽无自觉症状,但给患者精神上造成极大痛苦,严重影响美容和社会交往。 Chinese name: Luliconazole Chinese alias: 4 - (2,4-dichloro-phenyl) -1,3-dithiolane-2 fork -1- imidazolylacetonitrile English name: Luliconazole Indications Editing For the following fungal infections: ringworm - ringworm, tinea, jock itch; Candida infections - fingers erosive disease, intertrigo; vitiligo Development through Luliconazole Development Co., Ltd. is Japan's pesticide imidazole antifungals, began earlier non-clinical testing and clinical trials cream Ⅰ, Ⅱ clinical trial of the first stage, due to strategic reasons subsequently stopped the development process. The second phase Ⅱ clinical trials 1990s Japan Pola Chemical Pesticide Co., Ltd. signed an agreement with the joint development, Pola Chemical Corporation in 2001 and began cream Ⅲ clinical trials and clinical trial conducted Ⅰ and lotion Comparative tests with cream. Eventually the drug in June 2005 approved since July 20, 2005 under the trade name Hikaru ri U nn (Lulicon) listed, creams and lotions specifications are 1%, for the following fungal infections: ringworm - athlete's foot, body ringworm, jock itch; Candida infections - fingers erosion syndrome, intertrigo; vitiligo. Indications Features Luliconazole Luliconazole Fungal skin fungal infections of the skin tissue site results. Fungal infections can be distributed in the body parts of the skin, the highest incidence of the stratum corneum, the typical symptoms of ringworm, candida infection and vitiligo. Survey, fungal skin infections account for about 13 percent of patients dermatology outpatients, including 88.0% of patients with psoriasis, 8.5% of Candida infections in patients and 3.4% of patients with vitiligo, psoriasis disease, and there were 64.0% for athlete's foot . Ringworm disease is an intractable skin diseases, slow course, the treatment of high relapse rate, when the onset of inflammation significantly, surrounded by blisters, pus cells, scaling and crusting lesions and other phenomena, and with varying degrees of itching, severe affect people's normal life. Ringworm including tinea pedis, tinea, jock itch and so on. Athlete's foot is plantar dermatophytes violation of superficial fungal infections caused by the skin between the toes, commonly known as "athlete's foot." Athlete's foot is common throughout the world, is the highest incidence of fungal disease in one. In our cities, adult-onset rate of up to 60%, not only can infect themselves, can also infect others, is the root cause of ringworm, tinea, jock itch, and onychomycosis. Tinea occurred on the smooth skin of superficial fungal infections. Jock itch is especially occurs in the groin, perineum and anus around fungal skin infections. From the genus Candida is Candida infection, especially a fungal disease caused by Candida albicans. The pathogen can affects the skin and mucous membranes, but also visceral involvement. The most common skin infections, including Candida intertrigo fingers and erosion. Interphalangeal erosion is more common in long-term immersion in water operations personnel to 3-4 fingers most common dipping fingers pale skin, remove the skin dipping, showing clear boundaries moist surface, basal flushing, may have a small amount of exudate. Intertrigo occurred in parts of the skin folds acute inflammation, manifested as skin redness, swelling, wet, sweating, dipping epidermis, easy erosion and serous effusion, infection can form tiny pustules and ulcers, Vitiligo is acquired due to the limitations of the white patches of skin depigmentation occurred, is a common disease, is one of the chronic skin disease in three. Colored race in the world, a variety of ethnic may get sick. Worldwide incidence is about 1-2%. Of about 2%. Vitiligo although no symptoms, but caused great pain to the patient mentally, seriously affect the beauty and social interaction.
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