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  药店国别: 日本药房
产地国家: 日本
所属类别: 调节水、电解质药->电解质补充药
处方药:保健药品
包装规格: 500毫升 20包
计价单位:
   
生产厂家中文参考译名:
日本大冢
生产厂家英文名:
Otsuka
原产地英文商品名:
Bicarbon Injection 500ml 20bags
中文参考商品译名:
Bicarbon输液 500毫升 20包
原产地国家批准上市年份:
0000/00/00
英文适应病症1:
Lack of extracellular fluid
临床试验期:
完成
中文适应病症参考翻译1:
缺乏细胞外液
药品信息:

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详细处方信息以本药内容附件PDF文件(201411504405922.pdf)的“原文Priscribing Information”为准
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部分中文专司达处方资料(仅供参考)

Therapeutic category name Bicarbonate Ringer's solution

Brand Name Bikaneito infusion (500mL bag)

Composition

This agent is an injectable solution containing the following ingredients 1 container (500mL) in .

Sodium chloride 2.92g

Potassium chloride 0.15g

Calcium chloride hydrate 0.11g

Magnesium chloride 0.10g

Sodium hydrogen carbonate 1.175g

Sodium citrate hydrate 0.10g

This agent contains citric acid hydrate (pH adjusting agent ) as an additive .

Electrolyte concentration

Na + 130mEq / L

K + 4mEq / L

Mg2 + 2mEq / L

Ca2 + 3mEq / L

Cl- 109mEq / L

HCO3- 28mEq / L

Citrate3-※ 4mEq / L

Contraindication

Hypermagnesemia , worsening the hypermagnesemia by the electrolyte composition of [ the drug patients with hypothyroidism , there is a risk of or cause . ] Effect or efficacy

Supply, the correction of extracellular fluid in reducing the time of interstitial fluid and circulating blood volume , correction of metabolic acidosis.

Careful administration

There is a possibility that [ water , prone to overdose of the electrolyte , symptoms worsen patients with renal insufficiency .

There is a possibility to put a burden on the heart from the fact that increasing the circulating blood volume patients with heart failure , symptoms worsen . ] Is required to hydration in the patients of this hypertonic dehydration , there is a possibility that the symptoms worse by the administration of this drug , including the electrolyte . ]

There is a possibility that [ the water , you have overload of electrolyte patients with urine volume is reduced by obstructive urinary tract disease , symptoms worsen . ]

Pharmacology

A result of examining the amount excreted as carbon dioxide alkalizing agent using laparotomy invasive rats and normal , was formulated into the extracellular fluid replenisher is metabolized acetate and sodium lactate , formulated in acetate Ringer's solution and lactated Ringer's solution sodium bicarbonate as compared to sodium was formulated into the present agent 5 it is rapidly excreted in the expired air as carbon dioxide) .

In a study using a canine model invasive surgery that made the laparotomy - air exposure , the drug showed the same effects as those of the acetate Ringer's solution and lactated Ringer's solution with respect to the maintenance of blood acid-base balance and circulation dynamics . Level of magnesium in the blood of the group treated with this drug is 6 to maintain the level of pre-dose values) . Using a rat hemorrhagic shock model , was carried out (100mL/kg/hr administration , 25mL/kg/5min + 75mL/kg/hr administration ) 2 test . In the former , the agent 7 shown the same effect as the acetate Ringer's solution and lactated Ringer's solution for the improvement of blood acid-base balance and circulation dynamics ) . In the latter bolus , blood pressure, with respect to blood bicarbonate ion concentration and excess base , this drug showed rapid improvement as compared with the acetate Ringer's solution . Further , the 8 blood lactate value decreased rapidly than lactate Ringer's solution in this drug ) . In a study using rat liver resection under hemorrhagic shock model , blood lactate level was increased in the administration of Ringer's lactate , but 9 showed no change in this agent) .

更新日期: 2013-07-18
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