药品信息:
--------------------------------------------------------------- 详细处方信息以本药内容附件PDF文件(201142523414613.pdf)的“原文Priscribing Information”为准 --------------------------------------------------------------- 部分中文多索茶碱处方资料(仅供参考)
药品名称:多索茶碱
英文药名:Doxofylline
其他名称:Ansimar、Maxivent、安赛玛、安泰玛、多索菲林、枢维新。
药理作用:本品抑制磷酸二酯酶,松弛支气管平滑肌作用较氨茶碱强,另外对组胺诱发的豚鼠咳嗽具有镇咳作用。
临床应用:支气管哮喘及伴支气管痉挛的肺部疾病。
禁忌症:凡对多索茶碱或黄嘌呤的衍生物类药物过敏、急性心肌梗死患者及哺乳期妇女禁用。
不良反应:少数患者服药后有心悸、窦性心动过速、上腹不适、纳差、恶心、呕吐、兴奋、失眠等症状。
制剂规格: (1)片剂0.2g; (2)胶囊剂0.2g; (3)注射剂:100mg/ml。
注意事项: (1)患有甲亢、窦性心动过速、心律失常者,请遵医嘱用药。 (2)茶碱类药物个体差异较大,多索茶碱剂量亦要视个体病情变化选择最佳剂量和用药方法。与氟喹诺酮类药物联用时,剂量酌减。 (3)妊娠期妇女慎用。 (4)严重心、肺、肝、肾功能异常者以及活动性胃、十二指肠溃疡者慎用。
Doxofylline (Ansimar) Side Effects, Dosage, Interaction Information What is Doxofylline (Ansimar)? Doxofylline is a type of enzyme inhibitor drugs that is used to treat Asthma. In animal and human studies, it has shown similar efficacy to theophylline but with significantly less side effects. Doxofylline belongs to category of enzyme inhibitor activity drugs. Specifically, Doxofylline is a new generation long acting oral methylxanthine derivative. Methylxanthines are phosphodiesterase inhibitors. Doxofylline is available as the Brand Name, Ansimar. Doxofylline also has antitussive and bronchodilator affects, and acts as a phosphodiesterase inhibitor.
Indication for use of Doxofylline (Anismar) For maintenance therapy in patients suffering with Asthma and Chronic Obstructive Pulmonary Disease (COPD).
Side Effects of Doxofylline (Anismar) No CNS and CVS side effects. Doxofylline has a prolonged bronchodilator effect and unlike theophylline it has least adenosine interactions. It is highly safe in smokers. There is no sleep disturbances and no effects on gastric secretions with doxofylline.
Dosages of Doxofylline (Anismar) Adult:400mg once a day. Single dose, administration in the evening reduces nocturnal, symptoms and helps to keep the patients complaint free during the day.
However, in certain cases, 400mg twice daily is recommended on the basis of the clinical response. Doses as high as 1200mg/day (400mg 3 times day) may also be prescribed .
Precautions while using Doxofylline (Anismar) Initial treatment of acute episodes of bronchospasm.
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