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 详细处方信息以本药内容附件PDF文件（201271019010330.PDF）的“原文Priscribing Information”为准
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 部分中文丙酸氯倍他索处方资料（仅供参考）

【英文名称】Clobetasol propionate

【英文同义词】Olux;Psorex;cgp9555;GR-2/92;clobesol;Temovate;CCl 4725;Dermoval;GR 2/925;Dermovate

【中文名称】丙酸氯倍他索

【中文同义词】特美肤;丙酸氯倍他索;氯倍他索丙酸盐;丙酸氯倍他索(特美肤)

【用途】为肾上腺皮质激素和促肾上腺皮质激素类药
运动员慎用

【成份】丙酸氯倍他索
 
【适应症】适用于慢性湿疹、银屑病、扁平苔藓、盘状红斑狼疮、神经性皮炎、掌跖脓疱病等。

【规格】0.05%（10g：5mg）

【用法用量】外用。涂于患处，每日2次。

【不良反应】可在用药部位产生红斑、灼热、瘙痒等刺激症状，毛囊炎，皮肤萎缩变薄，毛细血管扩张。还可引起皮肤干燥，多毛，萎缩纹，增加感染的易感性等。长期用药可能引起皮质功能亢进症，表现为多毛、痤疮、满月脸、骨质疏松等症状。偶可引起变态反应性接触性皮炎。

【禁忌】 
1.对本药及基质成份过敏者和对其他皮质类固醇过敏者禁用；
2.细菌性、真菌性、病毒性等感染性皮肤病；
3.溃疡性皮肤病禁用。
 
【注意事项】 
1．本品属于强效皮质类固醇外用制剂，若长期、大面积应用或采用封包治疗，由于全身性吸收作用，可造成可逆性下丘脑-垂体-肾上腺(PHA)轴的抑制，部分患者可出现库欣综合征、高血糖及尿糖等表现，因此本药不能长期大面积应用，亦不宜采用封包治疗。
2．大面积使用不能超过2周；治疗顽固、斑块状银屑病，若用药面积仅占体表的5%～10%，可以连续应用4周。每周用量均不能超过50g。
3．不能应用于面部、腋部及腹股沟等皮肤折皱部位，因为即便短期应用也可造成皮肤萎缩、毛细血管扩张等不良反应。
4．如伴有皮肤感染，必须同时使用抗感染药物。如同时使用后，感染的症状没有及时改善，应停用本药直至感染得到控制。
5．不可用于眼部。

【孕妇及哺乳期妇女用药】妊娠期及哺乳期妇女慎用。孕妇不能长期大量、大面积使用。

【儿童用药】婴儿及儿童不宜使用。

【药物相互作用】如正在使用其他药品，使用本品前请咨询医师或药师。

【药理毒理】本品作用迅速，是目前临床应用的高效外用皮质类固醇中药效较强的一种。具有较强的毛细血管收缩作用，其抗炎作用为氢化可的松的112.5倍，倍他米松磷酸钠的2.3倍，氟轻松的18.7倍。全身不良反应为氟轻松的3倍，无水钠潴留作用，有一定的促进钠、钾排泄作用。

【药代动力学】外用后可通过完整皮肤吸收。吸收后与系统给予皮质类固醇在体内的代谢一样，主要在肝脏代谢，经肾脏排出。

【贮藏】密闭，阴凉处保存。

ERIC NAME: CLOBETASOL FOAM - TOPICAL (kloe-BAY-ta-sol)

BRAND NAME(S): Olux

USES: Clobetasol is used to treat certain scalp and skin conditions (e.g., psoriasis, dermatitis, rash). Clobetasol reduces the swelling, itching and redness that can occur in these types of conditions. This medication is a very strong (super-high-potency) corticosteroid.

HOW TO USE: Apply this medication to the scalp, usually twice daily in the morning and evening or as directed by your doctor.Learn all preparation and usage instructions in the product package, and ask your doctor or pharmacist if you have questions about any of the information.Use this medication only on the skin. However, do not use it on the face, groin or underarms unless directed to do so by your doctor.Wash and dry your hands before applying. Apply the prescribed amount of medication to the affected area and gently rub in. Do not bandage, wrap or cover the area unless directed to do so by your doctor.After applying the medication, wash your hands, unless you are using this medication to treat the hands. If applying this medication near the eyes, avoid getting it in the eyes because this may worsen or cause glaucoma. Also, avoid getting the medication in your nose or mouth. If you get the medication in your eyes, nose, or mouth, rinse with plenty of water.Use this medication exactly as prescribed. Do not increase your dose, take it more frequently, or use it for longer than 2 weeks in a row. Do not apply more than one 50-gram can in a given week unless directed by your doctor. Doing so could increase your risk of side effects.Inform your doctor if your condition persists or worsens after 2 weeks.

SIDE EFFECTS: Burning, stinging, itching, irritation, dryness, or redness may occur when this medication is first applied to the scalp/skin. This should disappear in a few days as your body adjusts to the medication. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.Tell your doctor immediately if any of these unlikely but serious side effects occur: stretch marks (striae), skin thinning/discoloration, excessive hair growth, acne, hair bumps (folliculitis).Skin infections can become worse when using this medication. Notify your doctor if redness, swelling or irritation does not improve.Rarely, it is possible this medication will be absorbed from the skin into the bloodstream. This can lead to side effects of too much corticosteroid. These side effects are more likely in children, and in people who use this medication for a long time or over large areas of the skin. Tell your doctor right away if any of the following side effects occur: unusual/extreme tiredness, weight loss, headache, swelling ankles/feet, increased thirst/urination, vision problems.A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

PRECAUTIONS: Before using clobetasol, tell your doctor or pharmacist if you are allergic to it; or to any other steroids (e.g., hydrocortisone, dexamethasone); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.Before using this medication, tell your doctor or pharmacist your medical history, especially of: poor blood circulation, diabetes, other skin/scalp conditions (e.g., rosacea, perioral dermatitis), immune system problems.Do not use if there is an infection or sore in the area to be treated.Rarely, using corticosteroid medications for a long time or over large areas of skin can make it more difficult for your body to respond to physical stress. Therefore, before having surgery or emergency treatment, or if you get a serious illness/injury, tell your doctor or dentist that you are using this medication or have used this medication within the past few months.Though it is unlikely, this medication may slow down a child's growth if used for a long time. The effect on final adult height is unknown. See the doctor regularly so your child's height can be checked.This medication should be used only when clearly needed during pregnancy. Discuss the risks and benefits with your doctor.It is not known whether this drug passes into breast milk when applied to the scalp/skin. Similar medications pass into breast milk when taken by mouth. Consult your doctor before breast-feeding.

DRUG INTERACTIONS: Your healthcare professional (e.g., doctor or pharmacist) may already be aware of any possible drug interactions and may be monitoring you for it. Do not start, stop or change the dosage of any medicine before checking with them first.Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: oral corticosteroids (e.g., prednisone), other topical corticosteroids (e.g., hydrocortisone), drugs that suppress the immune system (e.g., cyclosporine).This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist.

OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. This medicine may be harmful if swallowed.

NOTES: Do not share this medication with others. This medication has been prescribed for your current condition only. Do not use it later for other skin problems unless told to do so by your doctor. A different medication may be necessary in those cases.Laboratory and/or medical tests (such as adrenal gland function tests) may be performed periodically to monitor your progress or check for side effects, especially if you use this drug for an extended period of time or apply it over large areas of the body. Consult your doctor for more details.Inform all your doctors you use or have used this medication.

MISSED DOSE: If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double the dose to catch up.

STORAGE: Store at room temperature between 68-77 degrees F (20-25 degrees C) away from heat and open flame. Do not puncture the can. Do not store in the bathroom. Keep all medicines away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.MEDICAL ALERT: Your condition can cause complications in a medical emergency. For enrollment information call MedicAlert at 1-800-854-1166 (USA), or 1-800-668-1507 (Canada).

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 详细处方信息以本药内容附件PDF文件（201271019010330.PDF）的“原文Priscribing Information”为准
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