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  药店国别: 欧洲共同体药房
产地国家: 欧洲共同体国家
所属类别: 作用于呼吸系统药物->祛痰药物
处方药:处方药
包装规格: 100毫升/瓶
计价单位:
  点击放大  
生产厂家中文参考译名:
勃林格殷格翰
生产厂家英文名:
Boehringer Ingelheim
该药品相关信息网址1:
http://www.drugs.com/international/lasolvan.html
原产地英文商品名:
LASOLVAN SYRUP 100ml/bottle
原产地英文药品名:
AMBROXOL HYDROCHLORIDE
原产地英文化合物名称:
trans-4-[[(2-Amino-3,5-dibromo-phenyl)methyl]amino]-cyclohexanol hydrochloride
中文参考商品译名:
LASOLVAN糖浆 100毫升/瓶
中文参考药品译名:
盐酸氨溴索
中文参考化合物名称:
反式-4-[(2-氨基3,5-二溴苄基)氨基]环己醇
原产地国家批准上市年份:
0000/00/00
英文适应病症1:
Expectorant
临床试验期:
完成
中文适应病症参考翻译1:
祛痰
药品信息:

---------------------------------------------------------------
 部分中文氨溴索处方资料(仅供参考)
---------------------------------------------------------------

【通用名称】氨溴索   

【英文名称】Ambroxol   

【中文别名】安布索、沫舒痰、盐酸氨溴索、溴环己胺醇   

【英文别名】Ambmxol Hydochloride、Amramen、Lasolvan、Mueovent   

【成份】化学名称:反式-4-[(2-氨基3,5-二溴苄基)氨基]环己醇
 trans-4-[[(2-Amino-3,5-dibromo-phenyl)methyl]amino]-cyclohexanol hydrochloride   
分子式:C13H18Br2N2O   

【药理】本品属目前临床上使用最为广泛的祛痰剂。能刺激呼吸道界面活性剂的形成及调节浆液性与粘液性的分泌,可同时改进呼吸道纤毛区与无纤毛区的消除作用,降低痰液及纤毛的粘着力,进一步使痰容易咳出,且减轻咳嗽的现象。由于本品效果迅速确实,耐受性良好,可长期服用,故为一理想优异的祛痰良药。   
作用特点:   
1.具有独特的作用机转:刺激界面活性剂的形成与分泌。   
2.作用范围广:由肺泡(无纤毛区)到气管皆可作用。   
3.胃肠吸收良好:效果迅速确实。   
4.持续作用时间长达9~10小时。   
5.口服72小时后,可完全由尿中排除。   

【药动学】本药口服吸收迅速完全,0.5-3 小时血药浓度达峰值。单次口服本药 30mg,平均血药浓度峰值(Cmax)为 88.8ng/ml,主要分布于肺、肝、肾,血浆蛋白结合率为90%。生物利用度约为70%-80%。本药主要在肝脏代谢,90%由肾脏清除,代谢产物为溴邻氨基苯甲酸,其生物活性不明确。半衰期为 7 小时。口服给药后72小时约70%经尿排泄,能否经乳汁分泌尚不清楚。   

【适应症】祛痰   

【用法用量】用法用量:饭后吞服。成人及10岁以上的小孩:每日 3次,每次1片。5~10岁的小孩:每日3次,每次1/2片。长期治疗时剂量可减低为每日 2次。   
本药须由医师处方使用。   
包装:20片PTP铝箔盒装。   

【禁用慎用】怀孕时:诚如任何制剂,于怀孕的前三个月并不推荐使用。   

【不良反应】通常有良好的耐受性。只有少数患者有轻微的胃肠不适及过敏反应。   

【相互作用】交互作用:可与其他药物并用,尤其可与抗生素、皮质类固醇及支气管扩张剂等品并用。

Drug name: Lasolvan

Other names used:
Acocontin®
Aflegan®
Ambril®
Ambrohexal®
Ambrolex®
Ambrolos®
Ambrosol®
Ambrowel®
Ambroxan®
Amxol®

Active Ingredients:
Ambroxol

Therapeutic actions: Ambroxol is a strong expectorant. It enables sticky phlegm to be removed from the respiratory tract faster and more easily by enhancing the bronchial secretions that loosen congested phlegm. Ambroxol also releases and strengthens the cilia (tiny striking hairs inside the windpipe and bronchial tubes), which can then expel the abnormal phlegm with their conveyor-belt like action.

Ambroxol increases the body's production of surfactant, a substance that promotes the clearance mechanism for germs or other pathogens, which helps to overcome infection in the bronchi.

Furthermore, ambroxol has been shown to have local anesthetic properties which contribute to the soothing effect of the syrup.

Indications: Ambroxol is used with acute and chronic diseases of upper respiratory tracts concomitant with formation of viscous and hardly separated expectoration, for therapy of asthmatic bronchitis, bronchial asthma with hard expectoration elimination, bronchiectatic disease, chronic pneumonia, inflammatory diseases of rhinopharyngeal tracts (laryngitis, pharyngitis, sinusitis and rhinitis).

Contraindications and cautions: Hypersensitivity, pregnancy (I term), phenylketonuria (for medicinal forms, which contain aspartam). Proceed using by caution. Hepatic insufficiency.

Adverse effects: The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.

Allergic reactions: skin rash, hives, angioneurotic edema, sometimes - allergic contact dermatitis, anaphylactic shock.
Rare - weakness, headache, diarrhea, dry mouth and respiratory tract, exanthema, rhino-Rhea, bolts, dysuria.
During prolonged application at high doses - gastralgia, nausea, vomiting.
With rapid intra-venal introduction - feeling of torpor, adynamia, intensive headaches, a decrease AP, shortness of breath, hyperthermy, chill.
The side effects listed above may not include all of the side effects reported by the drug's manufacturer.

Interactions: Tell your doctor or pharmacist what medicines you are already taking, including those bought without a prescription and herbal medicines, before you start treatment with this medicine.

Joint application with antitussive drugs lead to difficult phlegm excretion and decreased cough. Lasolvan increases penetration of amoxicillin, tsefuroksim, erythromycin and doxyciclin into the bronchial secret.

Additional Information: DO NOT SHARE THIS MEDICINE with others. DO NOT USE THIS MEDICINE for other health conditions. KEEP THIS PRODUCT, as well as syringes and needles, if needed during treatment, out of the reach of children. Do not reuse needles, syringes, or other materials.

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 2011-2-15更新

更新日期: 2011-2-15
附件:


 
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