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  药店国别: 美国药房
产地国家: 美国
所属类别: 泌尿生殖系统及泌乳药物->生殖泌乳药
处方药:处方药
包装规格: 0.5毫克/片 8片/瓶
计价单位:
  点击放大  
生产厂家中文参考译名:
法玛西亚-普强
生产厂家英文名:
PHARMACIA AND UPJOHN
该药品相关信息网址1:
http://www.drugs.com/pro/dostinex.html
该药品相关信息网址2:
http://www.rxlist.com/dostinex-drug.htm
原产地英文商品名:
DOSTINEX 0.5mg/tab 8tabs/bottle
原产地英文药品名:
CABERGOLINE
中文参考商品译名:
DOSTINEX 0.5毫克/片 8片/瓶
中文参考药品译名:
卡麦角林
原产地国家批准上市年份:
1996/12/23
英文适应病症1:
Inhibition of physiological lactation
英文适应病症2:
Hyperprolactinemia
临床试验期:
完成
中文适应病症参考翻译1:
抑制生理性泌乳
中文适应病症参考翻译2:
高催乳素血症
药品信息:

友情提示:Dostinex品牌药暂时无货,订购时需先确认。

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 详细处方信息以本药内容附件PDF文件(201111718115932.pdf)的“原文Priscribing Information”为准
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部分中文卡麦角林处方资料(仅供参考)

【英文药名】Dostinex (Cabergoline Tablets)

【中文药名】卡麦角林片

【药品简介】
通用名称:卡麦角林
英文名称:Cabergoline
英文别名:Dostinex

【药理作用】卡麦角林为长效多巴胺D2-受体激动剂。它通过促进多巴胺的释放,反馈性抑制下丘脑的功能,进而降低催乳素的分泌。

【药代动力学】
吸收:口服胃肠道吸收。经历首过代谢效应。
分布:血浆蛋白结合率:约40%。
代谢:广泛代谢为无活性的代谢产物。
排泄:主要经粪便排泄。

【适应症】用于抑制生理性泌乳以及治疗高催乳素血症相关性疾病。

【用法用量】不同适应症的用法用量:
抑制生理性泌乳:成人:1mg,产后第1天一次性给药。肝损害:调整剂量。
抑制泌乳:成人:250mcg/12小时,持续2天。
高催乳素血症相关性疾病:
成人:初始剂量:500mcg/周,然后根据反应,每月加量500mcg,可每周一次给药或分2次在不同日期给药;药量超过1mg应当分次给药。
常规剂量:1mg/周,可高达:4.5mg/周。进餐时或餐后服用。

【药物过量】症状:鼻塞、晕厥或幻觉。处理:需要时,采取措施维持血压正常。

【禁忌】下列情况禁用:妊娠毒血症,有产后精神病史者,未控制的高血压,肝功能不全。对卡麦角林和麦角衍生物过敏者。

【注意事项】下列情况慎用:心血管疾病,雷诺氏综合征,肾脏或肝脏损害,消化性溃疡,胃肠道出血,精神疾病史,高血压。影响驾车和机械操作能力。长期或高剂量用药会导致精神问题、胸膜/腹膜后纤维化或心脏瓣膜纤维化。每月一次监测血清泌乳素水平直到正常。肝损害患者定期监测肝功能。

【不良反应】血压降低,头晕,眩晕,头痛,恶心,失眠,腹痛,消化不良,胃炎,虚弱,疲劳,便秘,呕吐,胸痛,热潮红,抑郁,麻刺感,腿痛性痉挛,雷诺氏综合征,伴有幻觉,错觉和意识混乱的精神异常。副作用呈剂量相关系,高剂量时发生副作用的可能性增加。

【药物相互作用】与抗高血压药合用,增加发生体位性低血压的风险。增强多巴胺的血管收缩作用。降低硝酸甘油的血管舒张作用。与选择性5-羟色胺再摄取抑制剂或三环类抗抑郁剂合用,增加发生5-羟色胺综合征的风险。
严重药物相互作用:与西布曲明合用,有发生5-羟色胺综合征的风险。

【FDA妊娠分级】B级:在动物繁殖研究中(并未进行孕妇的对照研究),未见到药物对胎儿的不良影响。或在动物繁殖性研究中发现药物有副作用,但这些副作用并未在设对照的、妊娠首3个月的妇女中得到证实(也没有在其后6个月具有危害性的证据)。

Brand Name
Dostinex

Common Name
cabergoline

DIN (Drug Identification Number)
02242471  DOSTINEX 0.5MG TABLET

How does this medication work? What will it do for me?
Cabergoline belongs to a class of medicines known as prolactin inhibitors. Prolactin inhibitors such as cabergoline are used to treat different types of medical problems that occur when too much of the hormone prolactin is produced by the pituitary gland, which is found in the brain. An excess production of prolactin can result in menstrual problems in women and fertility problems in men and women.

Cabergoline stops the brain from making and releasing prolactin from the pituitary gland. Cabergoline is also used to prevent the onset of normal lactation (milk production) in cases where there is a medical need to prevent lactation.

Your doctor may have suggested this medication for conditions other than the ones listed in these drug information articles. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not stop taking this medication without consulting your doctor.

Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it.

How should I use this medication?
When used to prevent the onset of normal lactation, the dose is 1 mg of cabergoline given as a single dose on the first day after having a baby.

For prolactin disorders, the recommended starting dose of cabergoline for adults is 0.5 mg per week, given in 1 or 2 doses per week (for 2 doses, the tablet is cut in half). The dose may be increased by 0.5 mg per week until a maximum of 2 mg per week is reached. The dose should not be increased more often than every 4 weeks. The eventual dose of the medication will depend on the results of lab tests that measure the amount of prolactin in your blood. After the tests have been in the normal range for at least 6 months, the doctor may decide to stop the medication and continue to monitor the levels of prolactin in the blood.

Many things can affect the dose of a medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

It is important to use this medication exactly as prescribed by your doctor. If you miss a dose, take it as soon as remembered if it is within 1 or 2 days of when you were supposed to take it. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

Store this medication in a dry place, away from heat and direct light.

Do not dispose of medications in wastewater (e.g. down the sink or in the toilet) or in household garbage. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.

What form(s) does this medication come in?
Each white, capsule-shaped tablet, scored one side, with the letters "P" and "U" on either side of the breakline, and the number "700" engraved on the other side, contains cabergoline 0.5 mg. Nonmedicinal ingredients: lactose anhydrous and leucine.

Some medications may have other generic brands available. Always ask your doctor or pharmacist about the safety of switching between brands of the same medication.
Who should NOT take this medication?

Cabergoline should not be taken by anyone who:
is allergic to cabergoline or any of the ingredients of the medication
is allergic to ergot derivatives (e.g., ergotamine)
has high blood pressure that is not controlled

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 详细处方信息以本药内容附件PDF文件(201111718115932.pdf)的“原文Priscribing Information”为准
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更新日期: 2012-6-19
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