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  药店国别: 新西兰药房
产地国家: 美国
所属类别: 抗病毒药物->抗艾滋病药物
处方药:处方药
包装规格: 150毫克/片 60片/盒
计价单位:
  点击放大  
生产厂家中文参考译名:
VIIV HLTHCARE
生产厂家英文名:
VIIV HLTHCARE
该药品相关信息网址1:
http://www.treathiv.com/?a=39
该药品相关信息网址2:
http://www.treathiv.com/safety/epivir.html
原产地英文商品名:
EPIVIR 150mg/tab 60tabs/box
原产地英文药品名:
LAMIVUDINE
中文参考商品译名:
益平维 150毫克/片 60片/盒
中文参考药品译名:
拉米夫定
原产地国家批准上市年份:
1995/12/17
英文适应病症1:
Human immunodeficiency virus
英文适应病症2:
HBV
临床试验期:
完成
中文适应病症参考翻译1:
人类免疫缺陷病毒
中文适应病症参考翻译2:
艾滋病毒
药品信息:

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 详细处方信息以本药内容附件PDF文件(2010122718525733.pdf)的“原文Priscribing Information”为准
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部分中文拉米夫定处方资料(仅供参考)

【成份】
拉米夫定 Lamivudine
【适应症】
与其它抗逆转录病毒药物联合使用,用于治疗人类免疫缺陷病毒(HIV)感染的成人和儿童。
【用量】
12岁以上患者 150 mg bid或300 mg qd。3月龄至12岁儿童 4 mg/kg bid,最大剂量为300 mg/天。肾损害者减量使用。参阅产品说明书。
【FDA妊娠分级】
C级: 动物研究证明药物对胎儿有危害性(致畸或胚胎死亡等),或尚无设对照的妊娠妇女研究,或尚未对妊娠妇女及动物进行研究。本类药物只有在权衡对孕妇的益处大于对胎儿的危害之后,方可使用。
【注意事项】
不要单独使用本药治疗。用药过程中注意监测胰腺炎的发生。使用核苷类似物后有出现乳酸酸中毒的报道,当患者出现原因不明的代谢性/乳酸酸中毒、进行性肝肿大或转氨酶迅速升高,应立即停止治疗。患肝肿大、肝炎或有肝脏疾病危险因素和脂肪肝的患者慎用。患有严重免疫缺陷的HIV感染患者在开始抗逆转录病毒药物治疗时,可引起无症状的或残余机会性感染的炎症反应,并导致严重的临床状况或症状恶化,如巨细胞病毒视网膜炎,分支杆菌感染和卡氏肺囊虫肺炎。妊娠的前3个月不要使用。感染HIV的母亲不应母乳喂养。
【不良反应】
血象异常,头痛、失眠,极罕见外周神经病或感觉异常,咳嗽、鼻部症状,胃肠道反应、罕见血清淀粉酶升高、胰腺炎,少见肝酶一过性升高、罕见肝炎,皮疹、脱发,关节痛、肌肉功能失调 、罕见横纹肌溶解,疲劳、不适、发热。
【药物相互作用】
勿与治疗卡氏肺囊虫肺炎及弓形体病时大剂量复方甲唑合用;不推荐与静注的更昔洛韦或膦甲酸盐;扎西他滨合用。

EPIVIR® (lamivudine)
See the full Prescribing Information for EPIVIR
Indication and Usage
EPIVIR in combination with other antiretroviral agents is indicated for the treatment of HIV infection. The use of EPIVIR is based on the results of clinical studies in HIV-infected patients in combination regimens with other antiretroviral agents. EPIVIR does not cure HIV infection/AIDS or prevent passing HIV to others.
Important Safety Information
EPIVIR, like other HIV medicines, can cause a condition called lactic acidosis and severe liver problems. Lactic acidosis occurs when acid builds up in the blood, which can affect how the body functions. In some cases, lactic acidosis can cause death. Nausea and tiredness that don't get better may be symptoms of lactic acidosis
If your child is taking EPIVIR, your doctor will tell you to watch carefully for signs and symptoms of an inflamed pancreas, such as, severe stomach pain, nausea and vomiting, mild fever, and clammy skin
Patients with hepatitis B virus (HBV) infection who take lamivudine, the active ingredient in EPIVIR, and then stop taking it, may get "flare-ups" of their hepatitis. A "flare-up" is when the disease suddenly returns in a worse way than before. If you have HBV infection, your doctor should closely monitor your liver function for several months after stopping lamivudine. You may need to take anti-HBV medicines
Worsening of liver disease (sometimes resulting in death) has occurred in patients infected with both HIV and hepatitis C virus who are taking anti-HIV medicines and are also being treated for hepatitis C with interferon with or without ribavirin. If you are taking EPIVIR as well as interferon with or without ribavirin, and you experience side effects, be sure to tell your doctor
When you start taking HIV medicines, your immune system may get stronger and may begin to fight infections that have been hidden in your body, such as pneumonia, herpes virus, or tuberculosis. If you have new symptoms after starting your HIV medicines, be sure to tell your doctor
Changes in body fat may occur in some patients taking antiretroviral therapy. These changes may include an increased amount of fat in the upper back and neck ("buffalo hump"), breast, and around the trunk. Loss of fat from the legs, arms, and face may also occur. The cause and long-term health effects of these conditions are not known at this time
The most common side effects with EPIVIR were headache, nausea, weakness or tiredness, and nasal signs and symptoms. In children, the most common side effects are fever, cough, skin rash, and an enlarged liver
These are not all the side effects you could have when taking this medicine. Your healthcare professional can talk to you about these and other side effects with EPIVIR
Tell your doctor promptly about any side effects or other unusual symptoms you may experience

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 详细处方信息以本药内容附件PDF文件(2010122718525733.pdf)的“原文Priscribing Information”为准
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于2011-3-22更新

更新日期: 2013-12-30
附件:


2010122718525733.pdf    



 
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