药品信息:
--------------------------------------------------------------- 详细处方信息以本药内容附件PDF文件(201061218181827.pdf)的“原文Priscribing Information”为准 --------------------------------------------------------------- 部分中文GAITY处方资料(仅供参考)
加替沙星
【化学名称】1-环丙基-6-氟-1,4-二氢-8-甲氧基-7-(3-甲基-1-哌嗪基)-4-氧代-3-喹啉羧酸
【分子式】C19H22FN3O4
【分子量】375.40
【药理毒理】加替沙星是DNA旋转酶抑制剂,同时也是拓扑异构酶Ⅳ抑制剂,DNA旋转酶(拓扑异构酶Ⅱ)是一种基本的维持DNA螺旋结构的细菌酶,在DNA复制、转录、修复、重组、转换移位中都是必不可少的。故加替沙星是杀菌性的。
【适应症】本品用于治疗由敏感病原体所致的各种轻、中度感染性疾病,包括慢性支气管炎急性发作,急性鼻窦炎,社区获得性肺炎,单纯性尿路感染(膀胱炎)和复杂性尿路感染,急性肾盂肾炎,男性淋球菌性尿路炎症或直肠感染和女性淋球菌性宫颈感染。
【不良反应】偶有一过性的刺激症状。
【禁忌】对加替沙星及其他喹诺酮类药物过敏者禁用。
【注意事项】1.不宜长期使用。2.使用中出现过敏症状,应立即停止使用。
【孕妇及哺乳期妇女用药】尚不明确。
Generic Name: gatifloxacin ophthalmic (GAT i FLOX a sin off THAL mik)
What is Zymar (gatifloxacin ophthalmic)? Gatifloxacin is an antibiotic in a group of drugs called fluoroquinolones (flor-o-KWIN-o-lones). Gatifloxacin fights bacteria in the body.
Gatifloxacin ophthalmic (for the eyes) is used to treat eye infections caused by bacteria. Gatifloxacin ophthalmic may also be used for other purposes not listed in this medication guide.
-----------------------------------------------------------
What is the most important information I should know about Zymar (gatifloxacin ophthalmic)? You should not use this medication if you allergic to gatifloxacin Before using this medication, tell your doctor if you have ever had an allergic reaction to gatifloxacin (Tequin) or similar medications such as levofloxacin (Levaquin), lomefloxacin (Maxaquin), moxifloxacin (Avelox), ofloxacin (Floxin), norfloxacin (Noroxin), and others.
Avoid wearing contact lenses while you still have active symptoms of the eye infection you are treating. Do not use other eye drops or medications during treatment unless otherwise directed by your doctor. Do not allow the dropper tip to touch any surface, including the eyes or hands. If the dropper becomes contaminated it could cause an infection in your eye, which can lead to vision loss or serious damage to the eye. Call your doctor at once if you have a serious side effect such as severe swelling, burning, redness, or discomfort, eye pain or vision changes, signs of new eye infection (drainage, crusting, or oozing), or the first sign of any skin rash, no matter how mild.
-----------------------------------------------------------
What should I discuss with my healthcare provider before using Zymar (gatifloxacin ophthalmic)? You should not use this medication if you allergic to gatifloxacin Before using this medication, tell your doctor if you have ever had an allergic reaction to gatifloxacin (Tequin) or similar medications such as levofloxacin (Levaquin), lomefloxacin (Maxaquin), moxifloxacin (Avelox), ofloxacin (Floxin), norfloxacin (Noroxin), and others.
FDA pregnancy category C. It is not known whether gatifloxacin ophthalmic is harmful to an unborn baby. Before using this medication, tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether gatifloxacin ophthalmic passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Do not use gatifloxacin eye drops in a child younger than 1 year old.
-----------------------------------------------------------
How should I use Zymar (gatifloxacin ophthalmic)? Use this medication exactly as prescribed by your doctor. Do not use it in larger amounts or for longer than recommended. Follow the directions on your prescription label.
You may need to use the eye drops every 2 hours for the first couple of days, and then every 4 hours for the rest of your treatment. Follow your doctor's instructions.
Wash your hands before using the eye drops. To apply the eye drops: Tilt your head back slightly and pull down your lower eyelid to create a small pocket. Hold the dropper above the eye with the dropper tip down. Look up and away from the dropper as you squeeze out a drop, then close your eye. Use only the number of drops your doctor has prescribed. Gently press your finger to the inside corner of the eye (near your nose) for about 1 minute to keep the liquid from draining into your tear duct. If you use more than one drop in the same eye, wait about 5 minutes before putting in the next drop.
Do not allow the dropper tip to touch any surface, including the eyes or hands. If the dropper becomes contaminated it could cause an infection in your eye, which can lead to vision loss or serious damage to the eye.
Do not use the eye drops if the liquid has changed colors or has particles in it. Call your doctor for a new prescription.
Store this medicine at room temperature away from moisture and heat. Do not freeze. Keep the bottle tightly closed when not in use.
-----------------------------------------------------------
What happens if I miss a dose? Use the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up the missed dose.
-----------------------------------------------------------
What happens if I overdose? You may rinse the eyes with warm water if you think you have used too much of this medicine. An overdose of gatifloxacin ophthalmic is not likely to cause life-threatening symptoms.
-----------------------------------------------------------
What should I avoid while using Zymar (gatifloxacin ophthalmic)? You should not wear contact lenses while you still have active symptoms of the eye infection you are treating.
Do not use other eye drops or medications during treatment unless otherwise directed by your doctor. Avoid caffeine while you are using gatifloxacin, because the medication can make the effects of caffeine stronger.
-----------------------------------------------------------
Zymar (gatifloxacin ophthalmic) side effects Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; slow heart rate, weak pulse, fainting; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have a serious side effect such as: severe swelling, burning, redness, or discomfort in or around your eye; eye pain, vision changes, increased sensitivity of your eyes to light; signs of new infection, such as drainage, crusting, or oozing of your eyes or eyelids; the first sign of any skin rash, no matter how mild.
Less serious side effects may include: mild itching, burning, redness, or irritation; watery eyes; puffy eyelids; headache; unpleasant taste in your mouth after using the drops.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
-----------------------------------------------------------
What other drugs will affect Zymar (gatifloxacin ophthalmic)? It is not likely that other drugs you take orally or inject will have an effect on gatifloxacin used in the eyes. But many drugs can interact with each other. Tell your doctor about all other medications you use, especially: theophylline (Elixophyllin, Theo-24, Uniphyl); a blood thinner such as warfarin (Coumadin); or cyclosporine used in the eyes (Restasis) or taken by mouth (Neoral, Sandimmune, Gengraf).
This list is not complete and there may be other drugs that can interact with gatifloxacin ophthalmic. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.
-----------------------------------------------------------
Where can I get more information? Your pharmacist can provide more information about gatifloxacin ophthalmic.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
--------------------------------------------------------------- 详细处方信息以本药内容附件PDF文件(201061218181827.pdf)的“原文Priscribing Information”为准 ---------------------------------------------------------------
2010年6月13日更新 |