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 详细处方信息以本药内容附件PDF文件（20106621561827.pdf）的“原文Priscribing Information”为准
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部分中文Karoxicam capsule处方资料（仅供参考）
 

學名:  Piroxicam (吡羅昔康)

劑型: 膠囊

编号:HK-49074

孕婦用藥分級:B；D (第三妊娠期)
 
藥理: 抑制體內環氧化酶(cyclooxygenase)I及II型，從而減少前列腺素(prostaglandin)的產生
 
用途: 治療急性及慢性類風濕性關節炎及骨關節炎的症狀
 
劑量: 口服每天一次，每次10毫克- 20毫克
 
用藥禁忌:
l 對Piroxicam及其藥物成份敏感的人士忌用
l 對阿士匹靈（Aspirin）或其他非類固醇消炎止痛藥（NSAIDs）敏感症者不宜服用此藥
l 急性消化道出血(active GI bleeding)
l 懷孕婦女(第三妊娠期)
 
用藥注意:
以下人士要小心使用：
l 充血性心臟衰竭
l 高血壓
l 肝、腎功能不全的人士
l 曾患有消化道潰瘍或出血
l 正在服用抗凝血藥(anticoagulants)或類固醇(corticosteroids)
 
常見副作用: 可引起腸胃不適、噁心、嘔吐、腹瀉
 
其他副作用: 皮疹、暈眩、水腫或消化道潰瘍
 
藥物相互作用:
l 此藥可增強抗凝血藥Warfarin(華法林)的功效，可能增加出血的機會
l 與其他非類固醇消炎止痛藥(NSAIDs)併用可能會增加藥物的副作用
 
病患者及家屬注意事項:
l 應在進餐時或餐後服用，以減輕腸胃不適的機會
l 如出現腸胃潰瘍或出血的徵兆或症狀時，應立即向醫生求診

Piroxicam

IMPORTANT WARNING:
People who take nonsteroidal anti-inflammatory medications (NSAIDs) (other than aspirin) such as piroxicam may have a higher risk of having a heart attack or a stroke than people who do not take these medications. These events may happen without warning and may cause death. This risk may be higher for people who take NSAIDs for a long time. Tell your doctor if you or anyone in your family has or has ever had heart disease, a heart attack, or a stroke, if you smoke, and if you have or have ever had high cholesterol, high blood pressure, or diabetes. Get emergency medical help right away if you experience any of the following symptoms: chest pain, shortness of breath, weakness in one part or side of the body, or slurred speech.

If you will be undergoing a coronary artery bypass graft (CABG; a type of heart surgery), you should not take piroxicam right before or right after the surgery.

NSAIDs such as piroxicam may cause ulcers, bleeding, or holes in the stomach or intestine. These problems may develop at any time during treatment, may happen without warning symptoms, and may cause death. The risk may be higher for people who take NSAIDs for a long time, are older in age, have poor health, or drink large amounts of alcohol while you are taking piroxicam. Tell your doctor if you take any of the following medications: anticoagulants ('blood thinners') such as warfarin (Coumadin); aspirin; other NSAIDs such as ibuprofen (Advil, Motrin) and naproxen (Aleve, Naprosyn); or oral steroids such as dexamethasone (Decadron, Dexone), methylprednisolone (Medrol), and prednisone (Deltasone). Also tell your doctor if you have or have ever had ulcers or bleeding in your stomach or intestines or other bleeding disorders. If you experience any of the following symptoms, stop taking piroxicam and call your doctor: stomach pain, heartburn, vomiting a substance that is bloody or looks like coffee grounds, blood in the stool, or black and tarry stools.

Keep all appointments with your doctor and the laboratory. Your doctor will monitor your symptoms carefully and will probably order certain tests to check your body's response to piroxicam. Be sure to tell your doctor how you are feeling so that your doctor can prescribe the right amount of medication to treat your condition with the lowest risk of serious side effects.

Your doctor or pharmacist will give you the manufacturer's patient information sheet (Medication Guide) when you begin treatment with piroxicam and each time you refill your prescription. Read the information carefully and ask your doctor or pharmacist if you have any questions.
 
Why is this medication prescribed?
Piroxicam is used to relieve pain, tenderness, swelling, and stiffness fness caused by osteoarthritis (arthritis caused by a breakdown of the lining of the joints) and rheumatoid arthritis (arthritis caused by swelling of the lining of the joints). Piroxicam is in a class of medications called NSAIDs. It works by stopping the body's production of a substance that causes pain, fever, and inflammation.

How should this medicine be used?
Piroxicam comes as a capsule to take by mouth. It is usually taken once or twice a day. Take piroxicam at around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take piroxicam exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Piroxicam will help control your symptoms but will not cure your condition. It may take 8-12 weeks or longer before you feel the full benefit of piroxicam.

Other uses for this medicine
Piroxicam is also sometimes used to treat gouty arthritis (attacks of severe joint pain and swelling caused by a build-up of certain substances in the joints) and ankylosing spondylitis (arthritis that mainly affects the spine). It is also sometimes used to relieve muscle pain and swelling, menstrual pain, and pain after surgery or childbirth. Talk to your doctor about the risks of using this medication for your condition.

What special precautions should I follow?
Before taking piroxicam,
tell your doctor and pharmacist if you are allergic to piroxicam, aspirin,or other NSAIDs such as ibuprofen (Advil, Motrin) and naproxen (Aleve, Naprosyn), or any other medications.
tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention the medications listed in the IMPORTANT WARNING section and any of the following: angiotensin-converting enzyme (ACE) inhibitors such as benazepril (Lotensin), captopril (Capoten), enalapril (Vasotec), fosinopril (Monopril), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), ramipril (Altace), and trandolapril (Mavik); diuretics ('water pills'); lithium (Eskalith, Lithobid); medications for diabetes; methotrexate (Rheumatrex); and phenytoin (Dilantin) .
tell your doctor if you have or have ever had asthma, especially if you also have frequent stuffy or runny nose or nasal polyps (swelling of the lining of the nose); swelling of the hands, feet, ankles, or lower legs ; or liver, or kidney disease.
tell your doctor if you are pregnant, especially if you are in the last few months of your pregnancy, you plan to become pregnant, or you are breast-feeding. If you become pregnant while taking piroxicam, call your doctor.
if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking piroxicam.
What special dietary instructions should I follow?   Return to top
Unless your doctor tells you otherwise, continue your normal diet.

What should I do if I forget a dose?
Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

What side effects can this medication cause?
Piroxicam may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
diarrhea
constipation
gas
headache
dizziness
ringing in the ears

Some side effects can be serious. If you experience any of the following symptoms or those mentioned in the IMPORTANT WARNING section, call your doctor immediately. Do not take any more piroxicam until you speak to your doctor.
vision problems
unexplained weight gain
fever
blisters
joint pain
rash
itching
hives
swelling of the eyes, face, lips, tongue, throat, arms, hands, feet, ankles, or lower legs
difficulty breathing or swallowing
hoarseness
pale skin
fast hearbeat
excessive tiredness
unusual bleeding or bruising
lack of energy
upset stomach
loss of appetite
pain in the upper right part of the stomach
flu-like symptoms
yellowing of the skin or eyes
cloudy, discolored, or bloody urine
back pain
difficult or painful urination

Piroxicam may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

What storage conditions are needed for this medicine?
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

In case of emergency/overdose
In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

Symptoms of overdose may include:
lack of energy
drowsiness
upset stomach
vomiting
stomach pain
bloody, black, or tarry stools
vomiting a substance that is bloody or looks like coffee grounds
difficulty breathing
coma (loss of consciousness for a period of time)

What other information should I know?
Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.

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 详细处方信息以本药内容附件PDF文件（20106621561827.pdf）的“原文Priscribing Information”为准
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