药品信息:
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--------------------------------------------------------------- 详细处方信息以本药内容附件PDF文件(201053121124636.pdf)的“原文Priscribing Information”为准 --------------------------------------------------------------- 部分中文Cefoxitin处方资料(仅供参考)
Cefoxitin 头孢西丁
药品名称 【分类】抗生素/β-内酰胺类/头孢菌素类 【别名】甲氧头孢噻吩、噻吩甲氧头孢菌素、头孢西丁、头孢西丁钠、先锋美吩、先锋美芬、头孢甲氧噻吩、头孢甲氧霉素、头霉噻吩、头霉甲氧噻吩。? 【外文名】Cefoxitin,Mefoxin,CFX,CefoxitinSodium,Boncefin,Cenomycin,Mefoxin,MK-306
适应症 本品为半合成第二代头孢菌素,特点为对革兰阴性菌有较强的抗菌作用,具有高度抗β内酰胺酶性质。抗菌谱包括大肠杆菌、肺炎杆菌、吲哚阳性的变形杆菌和沙雷氏菌、克雷白杆菌、流感杆菌、沙门菌、志贺菌等。对葡萄球菌和多种链球菌也有较好作用。临床主要用于敏感菌所致的呼吸道感染、心内膜炎、腹膜炎、肾盂肾炎、尿路感染、败血症以及骨、关节、皮肤和软组织等感染。
用法用量 成人1g~2g/次,3~4次/日,重症1日量可达12g;儿童(2岁以上)每日80mg~160mg/kg,分3~4次。肌注可用0.5%利多卡因注射液作溶剂。静注可将本品1g用10ml注射用水或生理盐水溶解,缓慢推注。如需静滴,可用生理盐水、葡萄糖注射液或0.167mol/L乳酸钠注射液溶解释。 任何疑问,请遵医嘱!
不良反应 1.过敏反应皮疹发生率约2%,有时有胃肠道反应、白细胞减少、氮血症及转氨酶升高等。 2.主要由肾排泄,偶可引起肾功能损害,对肾功能不全者应减量。 3.与青霉素有时有交叉变态反应,对青霉素过敏者应慎用。对头孢菌素类过敏者应禁用。
注意事项 1.参见头孢噻吩。 2.本品与多数头孢菌素均有拮抗作用,联合应用可致抗菌疗效减弱。
药物相互作用 本品与多数头孢菌素均有拮抗作用,配伍应用可抗菌疗效减弱。
Cefoxitin Sodium Injection About your treatment Your doctor has ordered cefoxitin, an antibiotic, to help treat your infection. The drug will be either injected into a large muscle (such as your buttock or hip) or added to an intravenous fluid that will drip through a needle or catheter placed in your vein for 30 minutes, two to four times a day.
Cefoxitin eliminates bacteria that cause many kinds of infections, including lung, skin, bone, joint, stomach, blood, gynecological, and urinary tract infections. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.
Your health care provider (doctor, nurse, or pharmacist) may measure the effectiveness and side effects of your treatment using laboratory tests and physical examinations. It is important to keep all appointments with your doctor and the laboratory. The length of treatment depends on how your infection and symptoms respond to the medication.
Precautions Before administering cefoxitin, tell your doctor and pharmacist if you are allergic to cefoxitin, any other cephalosporin [e.g., cefaclor (Ceclor), cefadroxil (Duricef), or cephalexin (Keflex)], penicillins, or any other drugs. tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially other antibiotics, probenecid (Benemid), and vitamins. tell your doctor if you have or have ever had kidney, liver, or gastrointestinal disease (especially colitis). tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking cefoxitin, call your doctor. if you have diabetes and regularly check your urine for sugar, use Clinistix or TesTape. Do not use Clinitest tablets because cefoxitin may cause false positive results.
Administering your medication Before you administer cefoxitin, look at the solution closely. It should be clear and free of floating material. Gently squeeze the bag or observe the solution container to make sure there are no leaks. Do not use the solution if it is discolored, if it contains particles, or if the bag or container leaks. Use a new solution, but show the damaged one to your health care provider.
It is important that you use your medication exactly as directed. Do not stop your therapy on your own for any reason because your infection could worsen and result in hospitalization. Do not change your dosing schedule without talking to your health care provider. Your health care provider may tell you to stop your infusion if you have a mechanical problem (such as a blockage in the tubing, needle, or catheter); if you have to stop an infusion, call your health care provider immediately so your therapy can continue.
Side effects Cefoxitin may cause side effects. If you are administering cefoxitin into a muscle, it probably will be mixed with lidocaine (Xylocaine) to reduce pain at the injection site. Tell your health care provider if any of these symptoms are severe or do not go away: diarrhea stomach pain upset stomach vomiting
If you experience any of the following symptoms, call your health care provider immediately: unusual bleeding or bruising difficulty breathing skin rash itching hives sore mouth or throat
Storing your medication Your health care provider probably will give you a several-day supply of cefoxitin at a time. If you are receiving cefoxitin intravenously (in your vein), you probably will be told to store it in the refrigerator or freezer. Take your next dose from the refrigerator 1 hour before using it; place it in a clean, dry area to allow it to warm to room temperature. If you are told to store additional cefoxitin in the freezer, always move a 24-hour supply to the refrigerator for the next day's use. Do not refreeze medications.
If you are receiving cefoxitin intramuscularly (in your muscle), your health care provider will tell you how to store it properly.
Store your medication only as directed. Make sure you understand what you need to store your medication properly.
Keep your supplies in a clean, dry place when you are not using them, and keep all medications and supplies out of reach of children. Your health care provider will tell you how to throw away used needles, syringes, tubing, and containers to avoid accidental injury.
In case of emergency/overdose In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.
Signs of infection If you are receiving cefoxitin in your vein or under your skin, you need to know the symptoms of a catheter-related infection (an infection where the needle enters your vein or skin). If you experience any of these effects near your intravenous catheter, tell your health care provider as soon as possible: tenderness warmth irritation drainage redness swelling pain
--------------------------------------------------------------- 详细处方信息以本药内容附件PDF文件(201053121124636.pdf)的“原文Priscribing Information”为准 ---------------------------------------------------------------
于2010年6月1日更新 |