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详细处方信息以本药内容附件PDF文件（201991622570812.pdf）的“原文Priscribing Information”为准
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部分中文盐酸雷尼替丁处方资料（仅供参考）

【英文名称】Ranitidine

【适用证】

雷尼替丁适用于：

1.活动性十二指肠溃疡的短期治疗。 大多数患者在4周内愈合。 迄今为止的研究尚未评估雷尼替丁在无并发症十二指肠溃疡中超过8周的安全性。

2.急性溃疡愈合后减少剂量的十二指肠溃疡患者的维持治疗。 没有进行过安慰剂对照的比较研究，持续时间超过1年。

3.病理性分泌过多症状的治疗（例如，Zollinger Ellison综合征和系统性肥大细胞增多症）。

4.急性溃疡愈合后减少剂量的胃溃疡患者的维持治疗。 安慰剂对照研究已进行1年。

5.治疗内镜诊断为糜烂性食管炎。 症状缓解胃灼热。

【用法用量】

活动性十二指肠溃疡

目前推荐的成人口服剂量雷尼替丁治疗十二指肠溃疡，每日两次，每次150毫克。晚餐后或就寝时间每日一次300mg的替代剂量可用于给药方便很重要的患者。一种治疗方案与特定患者人群相比的优势尚未得到证实（见临床药理学：

维持十二指肠溃疡的愈合：

目前推荐的成人口服剂量为睡前150毫克

病理性过度增生症（如Zollinger-Ellison综合征）：

目前推荐的成人口服剂量为150毫克，每天两次。在一些患者中，可能需要更频繁地施用雷尼替丁150mg剂量。剂量应根据患者的个体需求进行调整，并且只要临床指示就应继续。患有严重疾病的患者使用高达6克/天的剂量。

良性胃溃疡：

目前推荐的成人口服剂量为150毫克，每天两次。

维持胃溃疡的愈合：

目前推荐的成人口服剂量为睡前150毫克。

【禁忌】

雷尼替丁禁用于已知对药物或任何成分过敏的患者（参见注意事项）。

【INDICATIONS AND USAGE】

Ranitidine is indicated in:

1.Short-term treatment of active duodenal ulcer. Most patients heal within 4 weeks. Studies available to date have not assessed the safety of ranitidine in uncomplicated duodenal ulcer for periods of more than 8 weeks.

2.Maintenance therapy for duodenal ulcer patients at reduced dosage after healing of acute ulcers. No placebo-controlled comparative studies have been carried out for periods of longer than 1 year.

3.The treatment of pathological hypersecretory conditions (e.g., Zollinger Ellison syndrome and systemic mastocytosis).

4.Maintenance therapy for gastric ulcer patients at reduced dosage after healing of acute ulcers. Placebo-controlled studies have been carried out for 1 year.

5.Treatment of endoscopically diagnosed erosive esophagitis. Symptomatic relief of heartburn.

【CONTRAINDICATIONS 】

Ranitidine is contraindicated in patients known to have hypersensitivity to the drug or any of the ingredients (see PRECAUTIONS).

【DOSAGE AND ADMINISTRATION 】

Active Duodenal Ulcer

The current recommended adult oral dosage of ranitidine for duodenal ulcer is 150 mg twice daily. An alternative dosage of 300 mg once daily after the evening meal or at bedtime can be used for patients in whom dosing convenience is important. The advantages of one treatment regimen compared to the other in a particular patient population have yet to be demonstrated (see CLINICAL PHARMACOLOGY:

Maintenance of Healing of Duodenal Ulcers:

The current recommended adult oral dosage is 150 mg at bedtime

Pathological Hypers ecretory Conditions (such as Zollinger-Ellison syndrome):

The current recommended adult oral dosage is 150 mg twice a day. In some patients it may be necessary to administer ranitidine 150 mg doses more frequently. Dosages should be adjusted to individual patient needs, and should continue as long as clinically indicated. Dosages up to 6 g/day have been employed in patients with severe disease.

Benign Gastric Ulcer:

The current recommended adult oral dosage is 150 mg twice a day.

Maintenance of Healing of Gastric Ulcers:

The current recommended adult oral dosage is 150 mg at bedtime.

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详细处方信息以本药内容附件PDF文件（201991622570812.pdf）的“原文Priscribing Information”为准
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