药品信息:
--------------------------------------------------------------- 详细处方信息以本药内容附件PDF文件(201921320545211.pdf)的“原文Priscribing Information”为准 --------------------------------------------------------------- 部分中文Prepopik用于口服溶液的粉末处方资料(仅供参考)
【英文名称】PREPOPIK
【适用证】
Prepopik是一种吡硫酸钠,一种兴奋剂泻药,氧化镁和无水柠檬酸的组合,形成柠檬酸镁,一种渗透性泻药,用于清洁结肠,作为成人和9岁及以上儿科患者的结肠镜检查准备。
【禁忌症】
- 严重肾功能损害(肌酐清除率小于30 mL /分钟)(4)
- 胃肠道(GI)梗阻或肠梗阻(4)
- 毛巾穿孔(4)
- 毒性结肠炎或中毒性巨结肠(4)
- 胃保留(4)
- 对任何成分的过敏反应(4)
【用法用量】
准备和管理
每份Prepopik包装必须在摄入前用水溶解,并根据给药方案进行给药。直接摄入未溶解的粉末可能会增加恶心,呕吐和脱水的风险。 (2.2,5.8)
完成结肠镜检查准备需要两剂(每剂量一包)Prepopik。优选的方法是“分流 - 剂量”方法。替代方案是“前一天”方法。 (2.1)
在每种剂量的Prepopik中,在两种给药方案中必须消耗额外的液体。 (2.1,5.1)
每次服药开始后1小时内不要服用口服药物。 (2.1,7.2)
如果服用四环素或氟喹诺酮类抗生素,铁,地高辛,氯丙嗪或青霉胺,请在服用Prepopik前至少2小时和不少于6小时服用这些药物。 (2.1,7.3)
有关结肠镜检查和给药方案前的准备的完整信息,请参阅完整的处方信息。 (2.1,2.2,2.3)
【INDICATIONS AND USAGE】
Prepopik is a combination of sodium picosulfate, a stimulant laxative, and magnesium oxide and anhydrous citric acid which form magnesium citrate, an osmotic laxative, indicated for cleansing of the colon as a preparation for colonoscopy in adults and pediatric patients ages 9 years and older.
【Preparation and Administration】
Each packet of Prepopik must be dissolved with water prior to ingestion and administered according to the dosing regimen. Direct ingestion of the undissolved powder may increase the risk of nausea, vomiting and dehydration. (2.2, 5.8)
Two doses (one packet per dose) of Prepopik are required for a complete preparation for colonoscopy. The preferred method is the "Split-Dose" method. The alternative is the "Day Before" method. (2.1)
Additional fluids must be consumed after every dose of Prepopik in both dosing regimens. (2.1, 5.1)
Do not take oral medications within 1 hour of start of each dose. (2.1, 7.2)
If taking tetracycline or fluoroquinolone antibiotics, iron, digoxin, chlorpromazine, or penicillamine, take these medications at least 2 hours before and not less than 6 hours after administration of Prepopik. (2.1, 7.3)
For complete information on preparation before colonoscopy and administration of the dosage regimen, see full prescribing information. (2.1, 2.2, 2.3)
【CONTRAINDICATIONS】
-Severe renal impairment (creatinine clearance less than 30 mL/minute) (4)
-Gastrointestinal (GI) obstruction or ileus (4)
-Bowel perforation (4)
-Toxic colitis or toxic megacolon (4)
-Gastric retention (4)
-Hypersensitivity to any of the ingredients (4)
--------------------------------------------------------------- 详细处方信息以本药内容附件PDF文件(201921320545211.pdf)的“原文Priscribing Information”为准 --------------------------------------------------------------- |