您好,欢迎光临世界标品! 登录 注册(订药物标准品请用邮件联系我们)

SCITEK INTERNATIONAL (H.K.) LIMITED
Email: sciteck.hongkong@gmail.com
 

当前本网站药物产品种数共 8524 处方药 8148 非处方药 269 保健品/医疗用具 107

世界标品医药目录搜索(中英文):
世界各国官方药品目录搜索(英文):
世界标品医药知识搜索(中英文):

联系方式
国内客服电话:
国际免费电话:

咨询邮箱:
scimed.shanghai@shijiebiaopin.com
info@shijiebiaopin.com
pharmacy.shijiebiaopin1@gmail.com
pharmacy.shijiebiaopin2@gmail.com

  药店国别: 日本药房
产地国家: 日本
所属类别: 作用于呼吸系统药物->哮喘药物
处方药:处方药
包装规格: 112.5毫克/胶囊 100胶囊/盒
计价单位:
   
生产厂家英文名:
Ono
该药品相关信息网址1:
http://www.igenericdrugs.com/gd.cgi?notran=1&s=Pranlukast&search=SEARCH
原产地英文商品名:
Pranlukast (オノンドライシロップ10%)オノンカプセル 112.5mg 100caps
中文参考商品译名:
普仑司特112.5毫克/胶囊 100胶囊/盒
原产地国家批准上市年份:
0000/00/00
英文适应病症1:
Bronchial Asthma
临床试验期:
完成
中文适应病症参考翻译1:
支气管哮喘
药品信息:
中文别名: 普仑司特、普兰流卡斯特、哌鲁卡特 英文别名: Pranlukast Hydrate 生产企业: 药品类别: 其它抗变态反应药 药理药动 (1)白三烯(LT)受体拮抗作用。与LTC4、LTD4、LTE4受体选择性结合而拮抗其作用。几乎不影响花生烯酸酶,对乙酰胆碱、组织胺及5-羟色胺等无拮抗作用。 (2)抑制气管收缩作用。①可抑制由吸入LTC4、LTD4引起支气管哮喘患者的气管收缩。②可抑制支气管哮喘患者由吸人抗原引起的速发型或迟发型哮喘反应。③抑制支气管痉挛型哮喘患者的支气管收缩。④可抑制致敏的豚鼠由抗原引起的支气管收缩。⑤抑制豚鼠及人的离体气管平滑肌由LTC4、LTD4引起的收缩。 (3)抑制气管的过敏性:①改善支气管哮喘患者对乙酰甲胆碱的气管过敏性。②可抑制豚鼠因吸人抗原引起的气管乙酰胆碱或组织胺的反应亢进及由白三烯引起的气管收缩反应亢进。 (4)抑制气管的血管通透性及粘膜水肿(抗炎作用)。①可抑制豚鼠由抗原引起气管的血管通透性亢进。②静脉注射本品可抑制豚鼠由抗原诱发的及由LTC4、LTD4引起的气管粘膜水肿。 (5)改善肺功能。口服本品,可改善1秒量及最大呼气流量。 适 应 症 支气管哮喘。 用法用量 通常,成人每日450mg(4粒胶囊)分2次服,在早饭后及晚饭后口服。可根据年龄、症状适当增减。 [制剂与规格]胶囊剂:每粒胶囊含本品112.5mg。 不良反应 少见,一般在0.1%~5%以下。 (1)过敏:有时可见皮疹、瘙痒等。应停药并行适当处置。 (2)有时可有嗳气、呕吐、腹痛、胃部不适、腹泻、便秘等。 (3)有时出现GOT、GPT、胆红素升高。 (4)其它:有时可见胸部绞窄感、失眠、发热、蛋白尿等。 禁忌症 老年人生理机能降低,应减量。小儿应用本品尚无经验。 本品对妊娠的安全性尚未确定,妊娠或可能妊娠的妇女只有应用本品的益处大于可能发生的危险性时,才可应用。 Chinese alias: pranlukast, Champlain flow Custer, piperazine Lu Kate English Name: Pranlukast Hydrate Manufacturer: Drug Category: Other anti-allergic drugs Pharmacology, Pharmacokinetics   (A) leukotriene (LT) receptor antagonism. And LTC4, LTD4, LTE4 receptor selective binding and antagonism of its action. Almost no effect on arachidonic acid enzyme, acetylcholine, histamine and 5 pairs - such as serotonin no antagonism. (2) inhibiting airway contraction. ① inhibited by the inhalation of LTC4, LTD4 induced bronchoconstriction in patients with bronchial asthma. ② inhibit the rapid onset of bronchial asthma caused by the inhalation of antigen or late asthmatic reactions. ③ inhibition of bronchospasm in patients with asthma bronchoconstriction. ④ inhibit bronchial antigen sensitized guinea pig caused by the contraction. ⑤ suppression and human guinea pig isolated tracheal smooth muscle contraction by the LTC4, LTD4 caused. (3) inhibition of allergic airway: ① improve bronchial asthma methacholine airway hypersensitivity. ② inhibit antigen inhalation in guinea pigs caused by acetylcholine or histamine airway hyperactivity and by the reaction of leukotriene-induced bronchoconstriction reaction hyperthyroidism. (4) inhibition of airway mucosal vascular permeability and edema (anti-inflammatory effects). ① inhibited by the antigen-induced guinea pig tracheal vascular permeability. ② intravenous injection can inhibit guinea pig tracheal mucosal edema induced by the antigen and the LTC4, LTD4 caused. (5) to improve lung function. Oral administration, can improve one second volume and peak expiratory flow. Indications   Bronchial asthma. Dosage   Typically, adult daily 450mg (4 capsules) 2 times service, after breakfast and dinner after oral administration. According to age, symptoms appropriate changes. [Formulations and specifications] capsules: Each capsule contains the product 112.5mg. Adverse reactions   Rare, generally 0.1% to 5% or less. (1) Allergy: sometimes visible rash, itching. Parallel proper disposal should be discontinued. (2) sometimes belching, vomiting, abdominal pain, stomach upset, diarrhea, constipation. (3) sometimes GOT, GPT, bilirubin. (4) Other: sometimes visible chest strangulation flu, insomnia, fever, and proteinuria. Contraindications   Elderly physiological function decreases, should be reduced. FDA should no experience in children. The goods on the security of pregnancy has not been established, the FDA should benefit only the women who are pregnant or likely to be greater than the risk of pregnancy may occur when the application is available.
调控比例: 100%
订购表单下载
Copyrights © 2010,2011,2012 www.ShiJieBiaoPin.com, Inc., All rights Reserved www.ShiJieBiaoPin.com, Inc.
客服工作时间:太平洋时间18:00-24:00
国内客服电话:     国际免费电话:
友情提示:以上电话为免费电话,无需您承担任何费用,世界标品提供中文客服,请您放心拨打!
电子邮箱:sciteck.hongkong@gmail.com, 15901965168@163.com