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  药店国别: 德国药房
产地国家: 德国
所属类别: 神经系统药物->镇静、催眠、抗焦虑及抗惊厥药
处方药:处方药
包装规格: 150毫升
计价单位:
   
生产厂家英文名:
Eurim-Pharm Arzneimittel GmbH
原产地英文商品名:
Seroxat oral suspension 150ml
原产地英文药品名:
Paroxetine
中文参考商品译名:
赛乐特口服混悬液 150毫升
中文参考药品译名:
帕罗西汀
原产地国家批准上市年份:
0000/00/00
英文适应病症1:
depression
英文适应病症2:
depression accompanied by anxiety
英文适应病症3:
obsessive compulsive disorder
临床试验期:
完成
中文适应病症参考翻译1:
抑郁症
中文适应病症参考翻译2:
抑郁症的治疗伴有焦虑症
中文适应病症参考翻译3:
强迫症
药品信息:
适应症 各种类型鬱症及鬱症伴随焦虑症之症状治疗及预防復发、强迫症之症状治疗、恐慌症之症状治疗及预防復发、社交畏惧症(社交焦虑症)之治疗、泛焦虑症之症状治疗及预防復发(GAD)、创伤后压力症候群之治疗(PTSD)。 用法用量 1.忧鬱症:20mg,每日早上服用,逐渐增加剂量,最高每日50mg。 2.强迫症、恐慌症:每日40mg。 副作用 性慾降低、便秘、拉肚子、脸部朝红、胃口降低、肠胃不适、噁心、视觉模煳、呕吐、鼻塞、频尿、头痛等。 禁忌 已知对Seroxat有过敏反应者。 注意事项 1.如同所有精神科用药,对心脏方面疾病之患者,仍须小心使用。 2.癫痫及发作一如同其他抑鬱药,应小心使用于癫痫患者,如有癫痫发生则必须停药。 3.小孩使用本品安全性及有效性尚未建立,不推荐使用。 4.最好整粒吞服,请勿咀嚼。 5.根据病人的临床反应,每天逐增减,如突然中断,易产生以下的症状:如睡眠不足、昏眩、易受刺激。 6.本品会引起散瞳,对狭角性青光眼患者,仍应小心使用。 交互作用 1.本品抑制肝脏之cytochrome P450 CYP2D6。抑制CYP2D6可能造成由此 代谢的併用药物之血中浓度增加。这些包括某些三环抗忧鬱剂(例如:amitriptyline, nortriptyline, imipramine与desipramine),phenothiazine neuroleptics(例如:perphenazine与thioridazine),risperidone、atomoxetine,某些Type 1c抗心律不整剂(例如propafenone 与flecainide)和metoprolol。 2.与serotonergic药物(如L-tryptophan, triptans, tramadol, SSRIs, lithium, fentanyl及St. John's Wort - Hypericum perforatum - preparations)併用可能会导致5-HT 相关反应的发生(serotonin症状)。 3.如与Phenytoin併服会降低血中浓度,并增加其发生副作用的机率。 Seroxat - Seroxat is an antidepressant, selective serotonin reuptake inhibitor. This medication has a bicyclic structure distinct from the structures of other known antidepressants. Seroxat has antidepressant and anxiolytic effects when expressed enough incentive (activated) effect. Antidepressant (thymoleptic) action is related to the ability of Seroxat selectively block the reuptake of serotonin presynaptic membrane than is caused by increase of free content of this neurotransmitter in the synaptic cleft and enhancement of its activity in the CNS. Effect on the m-cholinergic receptors, alpha- and beta-adrenergic receptors is only slightly which determines the extremely weak intensity of the side effects. Seroxat, an antidepressant drug of the selective serotonin reuptake inhibitor (SSRI) type, has no active metabolites and has the highest specificity for serotonin receptors of all the SSRIs. It is used to treat depression resistant to other antidepressants, depression complicated by anxiety, panic disorder, social and general anxiety disorder, obsessive-compulsive disorder (OCD), premenstrual dysphoric disorder, premature ejaculation, and hot flashes of menopause in women with breast cancer. Indication: For the treatment of depression, depression accompanied by anxiety, obsessive compulsive disorder and panic attacks Adults: Treatment of major depressive disorder. Treatment of panic disorder with or without agoraphobia. Treatment of social anxiety disorder/social phobia. Seroxat CR has been shown to be effective in the treatment of social anxiety disorder/social phobia. The effectiveness of Seroxat CR tablets in the long-term treatment of social anxiety disorder/social phobia has not been evaluated. Therefore, if Seroxat CR is to be administered for extended periods in the treatment of social anxiety disorder/social phobia, the physician should periodically re-evaluate the long-term usefulness of Seroxat CR for the individual patient. Children and Adolescents <18 years: All Indications: Seroxat CR is not indicated for use in children or adolescents <18 years. Premenstrual Dysphoric Disorder (PMDD): Treatment of PMDD. The efficacy of Seroxat CR in the treatment of PMDD has been established in 3 placebo-controlled trials. The essential features of PMDD, according to DSM-IV, include markedly depressed mood, anxiety or tension, affective lability and persistent anger or irritability. Other features include decreased interest in usual activities, difficulty concentrating, lack of energy, change in appetite or sleep, and feeling out of control. Physical symptoms associated with PMDD include breast tenderness, headache, joint and muscle pain, bloating and weight gain. These symptoms occur regularly during the luteal phase and remit within a few days following onset of menses; the disturbance markedly interferes with work or school or with usual social activities and relationships with others. In making the diagnosis, care should be taken to rule out other cyclical mood disorders that may be exacerbated by treatment with an antidepressant. The effectiveness of Seroxat CR in long-term use, that is, for >3 menstrual cycles, has not been systematically evaluated in controlled trials. Therefore, the physician who elects to use Seroxat CR for extended periods should periodically re-evaluate the long-term usefulness of Seroxat CR for the individual patient. Indications: depression, obsessive-compulsive disorder, panic disorders, post-traumatic stress disorder, social anxiety disorder This medication is a selective serotonin reuptake inhibitor (SSRI) used to treat depression, panic attacks, obsessive-compulsive disorder (OCD), social anxiety disorder (social phobia), post-traumatic stress disorder (PTSD), and generalized anxiety disorders (GAD). Seroxat should not be used in children less than 18 years of age. It has not been shown to be effective for depression in children or teenagers. It may also cause serious side effects in this age group (see Side Effects section). Consult your doctor or pharmacist for more details. SSRI’s work by helping to restore the balance of certain natural substances in the brain (neurotransmitters).OTHER USES: This medication has also been used to treat a severe form of premenstrual syndrome (premenstrual dysphoric disorder- PMDD), sexual function problems in men (premature ejaculation), nerve problems associated with diabetes (diabetic neuropathy), and chronic headaches.
更新日期: 2014-04-01
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