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 详细处方信息以本药内容附件PDF文件（201432522311431.pdf）的“原文Priscribing Information”为准
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部分中文头孢他啶处方资料（仅供参考）

NAME OF DRUG: Fortum (ceftazidime).

DESCRIPTION:
Fortum belongs to the cephalosporin group of antibiotics. Fortum is used to treat severe infections of the respiratory tract (including pneumonia), skin, urinary tract, bone and joint, pelvic infections, intra-abdominal infections, septicaemia (serious bacterial infection of the blood) and meningitis (infection around the brain or spinal cord).
Fortum is a cephalosporin antibiotic for use by injection only. It is supplied as a white to faintly yellow powder in vials containing 1 g and 2 g ceftazidime (as pentahydrate) with sodium carbonate anhydrous (118 mg per gram of ceftazidime). On the addition of Water for Injections, Fortum Injection dissolves with effervescence to produce a solution for injection.
Fortum Injection contains approximately 52 mg (2.3 mEq) of sodium per gram of ceftazidime. 116 mg ceftazidime pentahydrate is equivalent to 100 mg ceftazidime free acid.
For laboratory tests associated with ceftazidime administration, ceftazidime pentahydrate should be used.

INDICATIONS:
Fortum is indicated for the treatment of single and mixed infections caused by susceptible aerobic organisms with suspected or documented resistance to other antimicrobials, but not to ceftazidime, and as an alternative to aminoglycosides in pseudomonal infection in patients in whom aminoglycoside toxicity is a cause for concern and other pseudomonal antibiotics cannot be used.
Indications include:
Severe infections in general:for example septicaemia, including neonatal sepsis,bacteraemia, and in patients in intensive care units with specific problems, eg, infected burns.
Respiratory tract infections: for example, pneumonia, broncho-pneumonia, infected pleurisy, infected bronchiectasis and bronchitis.
Severe ear, nose and throat infections: for example, otitis media, mastoiditis.Urinary tract infections: for example, acute and chronic pyelonephritis, pyelitis, cystitis,urethritis (bacterial only), and infections associated with bladder and renal stones.
Skin and soft tissue infections: for example, erysipelas, abscesses, cellulitis, infected burns and wounds, mastitis.
Gastrointestinal and abdominal infections: for example, intra-abdominal abscesses,enterocolitis.
Bone and joint infections: for example, osteitis, osteomyelitis, septic arthritis, infected bursitis.

CONTRAINDICATIONS:
Fortum is contraindicated in persons who have shown hypersensitivity to cephalosporins or who have experienced a major allergy to penicillin (anaphylaxis, angioneurotic oedema, urticaria).Lignocaine should not be used as a diluent for intramuscular injection in patients who are hypersensitive to lignocaine.

【商品名称】 复达欣
【成份】 本品主要成分为头孢他定。
【性状】 本品为白色或类白色结晶性粉末。
【适 应 症】 用于敏感革兰阴性杆菌所致的败血症、下呼吸道感染、腹腔和胆道感染、复杂性尿路感染和严重皮肤软组织感染等。对于由多种耐药革兰阴性杆菌引起的免疫缺陷者感染、医院内感染以及革兰阴性杆菌或铜绿假单胞菌所致中枢神经系统感染尤为适用。
【规格】 1.0g × 1 支
【用法用量】 静脉注射或静脉滴注。1．败血症、下呼吸道感染、胆道感染等，一日4～6g，分2～3次静脉滴注或静脉注射，疗程10～14日；2．泌尿系统感染和重度皮肤软组织感染等，一日2～4g，分2次静脉滴注或静脉注射，疗程7～14日。3．对于某些危及生命的感染、严重铜绿假单胞菌感染和中枢神经系统感染，可酌情增量至一日 0.15～0.2g／kg，分3次静脉滴注或静脉注射。4．婴幼儿常用剂量为一日30～100mg／kg，分2～3次静脉滴注。
【不良反应】 本品的不良反应少见而轻微。少数患者可发生皮疹、皮肤瘙痒、药物热；恶心、腹泻、腹痛；注射部位轻度静脉炎；偶可发生一过性血清氨基转移酶酶、血尿素氮、血肌酐值的轻度升高；白细胞、血小板减少及嗜酸性粒细胞增多等。
【禁 忌】 对头孢菌素类抗生素过敏者禁用。
【注意事项】
1．交叉过敏反应：对一种头孢菌素或头霉素（cephamycin）过敏者对其他头孢菌素或头霉素也可能过敏。对青霉素类、青霉素衍生物或青霉胺过敏者也可能对头孢菌素或头霉素过敏。
2．对青霉素过敏病人应用本品时应根据病人情况充分权衡利弊后决定。有青霉素过敏性休克或即刻反应者，不宜再选用头孢菌素类药。
3．有胃肠道疾病史者，特别是溃疡性结肠炎、局限性肠炎或抗生素相关性结肠炎（头孢菌素类很少产生伪膜性结肠炎）者应慎用。 4．肾功能明显减退者应用本品时，需根据肾功能损害程度减量。
5．对重症革兰阳性球菌感染，本品为非首选品种。
6．在不同存放 条件下，本品粉末的颜色可变暗，但不影响其活性。
7．对诊断的干扰：应用本品的病人直接抗球蛋白（Coombs）试验可出现阳性； 本品可使硫酸铜尿糖试验呈假阳性；血清丙氨酸氨基转移酶(ALT)、门冬氨酸氨基转移酶(AST)、 碱性磷酸酶、血尿素氮和血清肌酐 皆可升高。
8．以生理盐水、5%葡萄糖注射液或乳酸钠稀释成的静脉注射液（20mg/ml）在室温存放不宜超过24小时。
【药物相互作用】
1．本品与下列药物有配伍禁忌：硫酸阿米卡星、庆大霉素、卡那霉素、妥布霉素、新霉素、盐酸金霉素、盐酸四环素、盐酸土霉素、粘菌素甲磺酸钠、硫酸多粘菌素B、葡萄糖酸红霉素、乳糖酸红霉素、林可霉素、磺胺异恶唑、氨茶碱、可溶性巴比妥类、氯化钙、葡庚糖酸钙、盐酸苯海拉明和其他抗组胺药、利多卡因、去甲肾上腺素、间羟胺、哌甲酯、琥珀胆碱等。偶亦可能与下列药物发生配伍禁忌：青霉素、甲氧西林、琥珀酸氢化可的松、苯妥英钠、丙氯拉嗪、维生素B族和维生素C、水解蛋白。
2．在碳酸氢钠溶液中的稳定性较在其他溶液中为差。
3．本品不可与氨基糖苷类抗生素在同一容器中给药。与万古霉素混合可发生沉淀。
4．本品与氨基糖苷类抗生素或速尿等强利尿剂合用时需严密观察肾功能情况,以避免肾损害的发生。 　
【贮藏】密闭，在凉暗处保存。
【包装】支

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 详细处方信息以本药内容附件PDF文件（201432522311431.pdf）的“原文Priscribing Information”为准
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