药品信息: 效果或疗效
用于氨基酸补充剂的1-3年和婴儿新生儿以下状态。然而,新生儿和重2kg以上在出生作为一般规则。
低蛋白血症,营养不良,手术前后
剂量和用法
通常情况下, (体重超过2公斤出生)和新生儿作为氨基酸/ kg体重/天的量( 23 ~ 36毫升本文) 1.75 ~ 2.75克, 1-3年1.50婴儿~ 2.50克(本文中,我坚持用高热量的方法, 20 ~ 33ML ) /公斤体重/天灌入静脉滴注。
此外,我会根据临床症状,临床化验值进行调整。
注意事项
细心管理
(它应慎用于下列患者进行管理。 )
1 。
可加重酸中毒患者中毒程度高。 ]
2 。
可加重了心脏衰竭治疗充血性心脏衰竭。 ]
3 。
可加重低钠血症的[此药并不包括大多数娜患者低钠血症。 ]
副作用
的副作用,如概述表达状况
预先核准3箱子婴儿168箱子副作用的报道中( 1.8 % )的调查, 3 ( GPT )升高ALT含量2 ( GOT ), AST升高( 1.2 % ) ( 1.8 % ) , 1铝-P增加( 0.6 % ) (批准) 。
在上市后监测(药物使用调查,特别调查) ,共报告27案件994例( 2.7 % )的副作用。 4直接胆红素主要种的副作用, 6肝功能异常6 ( GPT ) ALT升高9的评论( GOT ), AST升高( 0.9 % ) ( 0.6 % ) ( 0.6 % ) ( 0.4 %)是(复试在结束) 。
其他副作用
1 。过敏症
频率未知
(皮疹等)
2 。消化系统
频率未知
(恶心,呕吐等)
3 。心血管
频率未知
(胸部不适,心悸等)
4 。肝脏
小于0.1-5%
黄疸(胆红素) ,增加AST( GOT) · ALT的(GPT ) ·阿尔-P
5 。质量 - 快速给药
频率未知
(该酸中毒质量 - 快速给药)
6 。他人
频率未知
(寒战,高热,头痛)
如果副作用观察到,这是适当的措施,如中止给药。
未知频率( ) :再评价结果, 15 ( 1979) ,由总氨基酸配方部分。
政府当局的孩子,等等。
(不足临床)尚未确定。安全性低出生体重儿出生时体重低于2公斤。
只有当确定治疗的好处是比我们的低出生体重儿净重2kg ,超越出身,原来少好风险,并适当地增加或减少剂量的临床症状,临床检验值,要谨慎服用。
另外994例,其中收集的(药物使用调查,特别调查)上市后监测,低出生体重儿体重的情况下, 2kg以下的比出生时为293例,副作用10箱子( 3.4 %)为报道他们。
3直接胆红素升高4 ( GOT ), AST升高( 1.4 % ) ( 1.0 % ) , 2条评论ALT (谷丙转氨酶)主要类型的副作用上涨( 0.7 % )
Effect or efficacy
Is used for amino acid supplementation following state in newborn infants , of 1-3 years and infants . However , newborn and weight 2kg or more at birth as a general rule .
Hypoproteinemia , malnutrition , before and after surgery
Dosage and usage
Usually , ( body weight more than 2kg at birth ) and newborn infants as the amount of amino acid / kg body weight / day (23 ~ 36mL this article ) 1.75 ~ 2.75g, the infants of 1-3 years 1.50 ~ 2.50g ( this article I persist instilled into the intravenous infusion by high-calorie method 20 ~ 33mL) / kg body weight / day .
In addition , I will be adjusted according to clinical symptoms , clinical laboratory values .
PRECAUTIONS
Careful administration
( It should be administered with caution in the following patients. )
1 .
May be aggravated the acidosis patients with a high degree of acidosis . ]
2 .
May be aggravated the heart failure patients with congestive heart failure . ]
3 .
May be aggravated hyponatremia for [ this drug does not include most of the Na patients with hyponatremia . ]
Side effect
Overview of side effects such as expression situation
A survey of pre-approval three cases infant 168 cases of side effects was reported in the ( 1.8% ) , 3 (GPT) increased ALT contents 2 (GOT) increased AST (1.2%), (1.8%) , 1 Al-P was increased ( 0.6% ) ( approval ) .
In post-marketing surveillance ( drug use investigation , Special Investigation ) , 27 cases of side effects in 994 cases ( 2.7% ) were reported . 4 bilirubin direct main kinds of side effects , 6 liver dysfunction 6 (GPT) increased ALT 9 reviews (GOT) increased AST (0.9%), (0.6%), (0.6%), (0.4%) it was ( re-examination at the end ) .
Other side effects
1 . Hypersensitivity
Frequency unknown
( Rash , etc.)
2 . Digestive
Frequency unknown
( Nausea , vomiting , etc.)
3 . Cardiovascular
Frequency unknown
( Chest discomfort , palpitations , etc.)
4 . Liver
0.1-5% less than
Jaundice ( bilirubin ) , increased AST (GOT) · ALT of (GPT) · Al-P
5 . Mass - rapid administration
Frequency unknown
( The acidosis by mass - rapid administration )
6 . Others
Frequency unknown
( Chills , fever , headache )
If side effects are observed, and it is appropriate measures such as discontinuing administration .
Of unknown frequency ( ) : re-evaluation result 15 ( 1979 ) , by section of the total amino acid formulation .
Administration to children , etc.
( Insufficient clinical ) has not been established. Safety for low birth weight infants weighing less than 2kg at birth .
Only when it is determined that therapeutic benefit is better than our original risk for low birth weight infants weighing 2kg less than birth , and be appropriately increased or decreased the dose clinical symptoms , clinical laboratory values , to be administered with caution .
In addition , 994 cases in which were collected post-marketing surveillance in ( drug use investigation , Special Investigation ) , low birth weight infants cases of body weight 2kg less than at birth is 293 cases , side effects 10 cases of (3.4 %) were reported them .
3 direct bilirubin rise 4 (GOT) increased AST (1.4%), (1.0%), 2 reviews ALT (GPT) rising main types of side effects ( 0.7% )