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  药店国别: 英国药房
产地国家: 英国
所属类别: 影响血液及造血系统药物->抗贫血药物
处方药:非处方药
包装规格: (304毫克/100毫克)/片 28片/盒
计价单位:
  点击放大  
生产厂家中文参考译名:
UCB
生产厂家英文名:
UCB
该药品相关信息网址1:
http://www.netdoctor.co.uk/medicines/100002129.html
该药品相关信息网址2:
http://www.epgonline.org/viewdrug.cfm/letter/p/language/lg0001/drugId/DR000861/drugName/PREGADAY
原产地英文商品名:
Pregaday (304mg/100mg)/tab 28tabs/box
原产地英文药品名:
Ferrous fumarate/folic acid
中文参考商品译名:
Pregaday (304毫克/100毫克)/片 28片/盒
中文参考药品译名:
富马酸亚铁/叶酸
原产地国家批准上市年份:
0000/00/00
英文适应病症1:
Anemia in pregnant women
英文适应病症2:
Pregnant women lack iron and folate
临床试验期:
完成
中文适应病症参考翻译1:
孕妇贫血
中文适应病症参考翻译2:
孕妇铁和叶酸缺乏
药品信息:

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 部分中文Pregaday处方资料(仅供参考)
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    在英国上市的Pregaday®片(含富马酸亚铁和叶酸,其中含铁100mg、叶酸350μg),用于预防孕妇铁和叶酸缺乏,成为畅销的OTC药物,并为英国药典所收载

名称:富马酸亚铁叶酸片

注册分类:化药3.2类

适应症:本品用防治孕妇贫血。
    常用的补血剂为硫酸亚铁,本品同硫酸亚铁一样系二价铁制剂,与硫酸亚铁相比,有显著特点。非孕妇女每日叶酸需求量为50~100μg,妊娠后,叶酸需要量增加,孕妇每日需要量为300~400μg,多胎妊娠时需要量更多。妊娠期补充叶酸除用于治疗巨幼红细胞性贫血之外,还可以用于预防胎儿神经管畸形等作用。富马酸亚铁与叶酸“孪生”制剂,方便孕妇使用,可以预防生育缺陷,提高缺铁性贫血同时伴有叶酸缺乏时铁剂的疗效,事半功倍。

特点
1、 复方制剂。
2、 较稳定,较难被氧化为三价铁。
3、 刺激性小,不良反应轻。
4、 起效快,人服后血清铁值很快上升。
5、 铁量高,富马酸亚铁中铁的含量为33%。
    根据WHO报告,亚洲孕妇贫血患病率为40%。国内资料表明,妊娠期合并贫血发生率达30%以上。妊娠贫血以缺铁性贫血最为常见,约占68%。对妊娠期血清铁蛋白、叶酸和VitB12的含量检测资料显示:血清铁血蛋白、叶酸的含量随孕期增长而降低。
 
Pregaday
Main use:Preventing iron and folic acid deficiency in pregnancy
Active ingredient:Ferrous fumarate, folic acid
Manufacturer:Celltech

How does it work?
This medicine contains two active ingredients, ferrous fumarate and folic acid. Ferrous fumarate is a form of iron and folic acid is a member of the B group of vitamins.

Both iron and folic acid are needed by the body for the formation of red blood cells. If the body does not receive adequate amounts of these nutrients, anaemia can develop.

During pregnancy the daily requirement for both iron and folic acid increases. This is because the mother must increase her production of red blood cells to supply the foetus and, in addition, the foetus and placenta need their own supply of iron, which can only be obtained from the mother.

If a pregnant woman doesn't increase her iron and folic acid intake, either through her diet or by taking supplements, she may become anaemic.

This iron and folic acid supplement is designed for use by pregnant women who are at high risk of developing iron and folic acid deficiency during the second and third trimesters of pregnancy. This may include women carrying twins or triplets and women who have had pregnancies close together. The supplement will also correct mild iron deficiency anaemia if this has already developed before the supplements are started. Talk to your doctor or pharmacist about whether you need to take an iron and folic acid supplement.

The absorption of iron from the gut is decreased if it is taken at the same time as coffee, tea, eggs or milk. Its absorption is enhanced if it is taken at the same time as foods or supplements containing vitamin C (ascorbic acid).

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What is it used for?
Preventing iron and folic acid deficiency in pregnancy

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Warning!
This medicine may discolour the stools, but this is harmless.

This medicine should be taken with food to minimise any digestive side effects.

This medicine contains iron and so should be kept well out of the sight and reach of children, as iron overdose can be fatal in children.

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Use with caution in
People who have had all or part of their stomach surgically removed (gastrectomy)

People with treated or controlled peptic ulcers

People with tumours that are dependent on folate for growth

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Not to be used in
Active peptic ulcer
Children
Crohn's disease
Genetic disease resulting in too much iron storage in the tissues (haemochromatosis)
Individuals receiving repeated blood transfusions
Inflammation of the bowel and back passage (ulcerative colitis)
Iron storage disorder (haemosiderosis)
Sudden loss of haemoglobin (oxygen carrying protein in the blood) in the urine at night (paroxysmal nocturnal heamoglobinuria)
Treatment of folate deficiency anaemia
Vitamin B12 deficiency (pernicious anaemia)

This medicine should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy.

If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately.

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Pregnancy and Breastfeeding
Certain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, before using any medicine.

This medicine is recommended and safe to take during pregnancy.

This medicine passes into breast milk, however there are no reported harmful effects when used by breastfeeding mothers.

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Side effects
Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.

Abdominal pain
Constipation
Diarrhoea
Nausea and vomiting
Loss of appetite
Darkening of stools
Allergic reaction to active ingredient

The side effects listed above may not include all of the side effects reported by the drug's manufacturer.

For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.

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How can this medicine affect other medicines?
Iron can supplements can affect the absorption of a number of medicines from the gut. For this reason, it is recommended that iron supplements are taken at least two hours before or two hours after other medicines, in order to minimise this effect. The medicines for which this is most important are listed below:

Iron supplements reduce the absorption of tetracycline-type antibiotics, eg oxytetracycline, doxycycline, minocycline, tetracycline, from the gut. These antibiotics may therefore be less effective if iron is taken at the same time. These antibiotics also reduce the absorption of the iron supplements from the gut. Separate the medicines by at least two hours.

Iron supplements also reduce the absorption of quinolone-type antibiotics, eg ciprofloxacin, norfloxacin, ofloxacin, levofloxacin, from the gut. These antibiotics may therefore be less effective if iron is taken at the same time. Separate the medicines by at least two hours.

Iron supplements also decrease the absorption of the following medicines from the gut:
- penicillamine
- bisphosphonates, eg alendronate
- methyldopa
- levodopa and carbidopa
- thyroxine

Iron supplements can therefore make these medicines less effective if they are taken at the same time. Separate the medicines by at least two hours.

Zinc supplements reduce the absorption of iron supplements, and iron supplements reduce the absorption of zinc supplements. Separate the medicines by at least two hours.

Antacids such as magnesium trisilicate, magnesium carbonate, magnesium hydroxide, aluminium hydroxide, calcium carbonate and sodium bicarbonate, may decrease the absorption of iron from the gut and thereby make the supplements less effective. Separate the medicines by at least two hours.

Trientene, used to treat Wilson's disease, also reduces the absorption of iron supplements from the gut, making them less effective unless the doses are separated by at least two hours.

Certain foods including milk, milk containing products, tea, coffee and eggs, may decrease iron absorption from the gut, while vitamin C (ascorbic acid) increases it.

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Other medicines containing the same active ingredients
Galfer FA 

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更新日期: 2013-12-10
附件:


 
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