您好,欢迎光临世界标品! 登录 注册(订药物标准品请用邮件联系我们)

中国医药研发对照标品提供商
Non-clinical Research-used
Medicine Sample Provider

当前本网站药物产品种数共 8473 处方药 8099 非处方药 268 保健品/医疗用具 106

世界标品医药目录搜索(中英文):
世界各国官方药品目录搜索(英文):
世界标品医药知识搜索(中英文):

联系方式
国内客服电话:
国际免费电话:


QQ客服1:1793093587
QQ客服2:1586083059
QQ客服3:2786706041
QQ客服6:2992753224
QQ客服7:2394834588

咨询邮箱:
scimed.shanghai@shijiebiaopin.com
info@shijiebiaopin.com
pharmacy.shijiebiaopin1@gmail.com
pharmacy.shijiebiaopin2@gmail.com

  药店国别: 美国药房
产地国家: 美国
所属类别: 泌尿生殖系统及泌乳药物->尿失禁、尿急和尿频
处方药:处方药
包装规格: 15毫克/片 100片
计价单位:
  点击放大  
生产厂家中文参考译名:
强生制药
生产厂家英文名:
JANSSEN PHARMS
该药品相关信息网址1:
http://www.oneyao.net/article/2009/1028/15492.html
该药品相关信息网址2:
http://www.medilexicon.com/drugs/gelnique.php
原产地英文商品名:
DITROPAN XLExtended Release 15 MG/Tab 100 Tablets
原产地英文药品名:
OXYBUTYNIN CHLORIDE
中文参考商品译名:
奥昔布宁缓释片 15毫克/片 100片
中文参考药品译名:
氯化奥昔布宁
原产地国家批准上市年份:
2009/01/27
英文适应病症1:
For the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and frequency(OAB)
临床试验期:
完成
中文适应病症参考翻译1:
治疗以尿急、失禁和尿频为症状的膀胱过度活动症(OAB)
药品信息:

Information on GELNIQUE

Gelnique (oxybutynin chloride) is an antispasmodic, antimuscarinic agent. It acts as a competitive antagonist of acetylcholine at postganglionic muscarinic receptors, resulting in relaxation of bladder smooth muscle. In conditions characterized by involuntary detrusor contractions, cystometric studies have demonstrated that oxybutynin increases maximum urinary bladder capacity and increases the volume to first detrusor contraction.

Mechanism of Action
Gelnique (oxybutynin chloride) is an antispasmodic, antimuscarinic agent. It acts as a competitive
antagonist of acetylcholine at postganglionic muscarinic receptors, resulting in relaxation of bladder smooth muscle. In conditions characterized by involuntary detrusor contractions, cystometric studies have demonstrated that oxybutynin increases maximum urinary bladder capacity and increases the volume to first detrusor contraction.

Indication
Gelnique is specifically indicated for the treatment of overactive bladder with symptoms of urge
urinary incontinence, urgency, and frequency.

USAGE Dosage
Gelnique is supplied as a gel designed for topical administration. The recommended initial dose of the
drug is one sachet (a 1 gram unit dose (1.14 mL) of 100 mg/g) applied once daily to dry, intact skin on the abdomen, upper arms/shoulders, or thighs. Application sites should be rotated.

Side Effects
Adverse events associated with the use of Gelnique may include, but are not limited to, the following:
dry mouth
urinary tract infection
application site reactions
upper respiratory tract infections
dizziness
nasopharyngitis

Storage
Store at 25°C (77°F);excursions permitted to 15-30°C (59-86°F).See USP controlled room temperature.
Protect from moisture and humidity. Apply immediately after the sachets are opened and contents expelled.Discard used sachets in household trash in a manner that prevents accidental application or ingestion by children, pets, or others.
Keep out of reach of children.

------------------------------------------------------
详细处方信息以本药内容附件PDF文件(201011209350133.pdf)的“原文Priscribing Information”为准
------------------------------------------------------
部分中文 GELNIQUE 处方信息(仅供参考)

       美国FDA批准沃森公司(Watson)的10%氯化奥昔布宁凝胶(oxybutynin chloride,Gelnique)上市,首个和唯一用于治疗以尿急、失禁和尿频为症状的膀胱过度活动症(OAB)。目前美国的OAB治疗药市场年销售额逾18亿美元,且逐年增长。
       本品为OAB患者提供了不同于口服的新有效治疗理念。由于本品中的药物经皮释药,不会像口服奥昔布宁制剂被肝脏代
谢。因而,诸如口干和便秘等不良反应的发生率低。 临床研究显示,本品作用强、患者耐受性好和此独特的释药系统可作为OAB患者的一线治疗药。
        本品是可快速干燥清澈无色无芳香剂的氯化奥昔布宁亲水凝胶制剂,一日1次涂于大腿、腹部、上臂或肩,1 g凝胶(
含氯化奥昔布宁100 mg)可持续释药24小时,提供了强效且耐受性好的外用制剂。
        本品获准上市是基于对789例OAB患者双盲安慰剂对照的Ⅲ期临床评价的研究结果。12周以上的研究,一日1次本品用药
组解除OAB症状(减少尿失禁的发生率和尿频的次数,增加尿排空量)优于安慰剂组。治疗组患者耐受性好,不良反应发生率低,无治疗引起的严重不良反应。最常见的不良反应为口干和用药部位局部反应。
        另外的药理学研究证明,本品使用1小时或以后、用前或用后30分钟使用遮光剂均不显著影响药物的吸收。

------------------------------------------------------
详细处方信息以本药内容附件PDF文件(201011209350133.pdf)的“原文Priscribing Information”为准
------------------------------------------------------

更新于2011年1月12日

更新日期: 2013-04-09
附件:






201011209350133.pdf    

 
调控比例: 100%
订购表单下载
Copyrights © 2010,2011,2012 www.ShiJieBiaoPin.com, Inc., All rights Reserved www.ShiJieBiaoPin.com, Inc.
客服工作时间:太平洋时间18:00-24:00
国内客服电话:     国际免费电话:
友情提示:以上电话为免费电话,无需您承担任何费用,世界标品提供中文客服,请您放心拨打!
电子邮箱:info.shijiebiaopin.com@gmail.com, info@shijiebiaopin.com