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  药店国别: 美国药房
产地国家: 美国
所属类别: 激素内分泌药物->更年期症状
处方药:处方药
包装规格: 42.5克/管
计价单位:
  点击放大  
生产厂家中文参考译名:
WARNER CHILCOTT
生产厂家英文名:
WARNER CHILCOTT
该药品相关信息网址1:
www.drugs.com/estrace.html
该药品相关信息网址2:
www.rxlist.com/estrace-drug.htm
该药品相关信息网址3:
www.rxlist.com/estrace-vaginal-cream-drug.htm
原产地英文商品名:
ESTRACE 0.01% CREAM 42.5G/TUBE
原产地英文药品名:
ESTRADIOL
中文参考商品译名:
ESTRACE 0.01%乳膏 42.5克/管
中文参考药品译名:
雌二醇
原产地国家批准上市年份:
1984/01/31
英文适应病症1:
Menopausal syndrome
英文适应病症2:
Lack of estrogen
英文适应病症3:
Acne
英文适应病症4:
Leukopenia
英文适应病症5:
Contraception
临床试验期:
完成
中文适应病症参考翻译1:
更年期综合征
中文适应病症参考翻译2:
雌激素不足
中文适应病症参考翻译3:
痤疮
中文适应病症参考翻译4:
白细胞减少症
中文适应病症参考翻译5:
避孕
药品信息:

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 详细处方信息以本药内容附件PDF文件(20127919435826.PDF,20127919435311.PDF)的“原文Priscribing Information”为准
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 部分中文雌二醇处方资料(仅供参考)

英文药名: Estrace (Estradiol Cream)

中文药名: 雌二醇阴道霜

药品名称
雌二醇 Estradiol

规格
片剂 Estrace:0.5mg、1mg、2mg。
经皮系统Estraderm:0.025mg、0.05mg、0.75mg、0.1mg。

适应症
女性性腺功能不良、双侧卵巢切除术后、萎缩性阴道炎、外阴干皱、更年期综合征中的潮热和出汗等及功能性子宫出血、人工月经周期,也可用于转移性乳腺癌、晚期前列腺癌及由于雌激素不足而引起的骨质疏松的进展,尚可用于痤疮、恶性肿瘤经化疗或放疗引起的白细胞减少症、事后避孕及回奶。

用法用量
口服,治疗绝经期症状,1mg~2mg/日,共3周,然后停药1周,最后10~13日可加用孕激素。
经皮,用于雌激素替补疗法或绝经期症状,以0.05mg或0.1mg的经皮给药系统(贴片)敷于躯体的清洁干燥皮肤上(最好敷于臂部上方,每周轮流一侧),2次/周,可采用3周用药,1周停用,最后10~13日加用孕激素。或遵医嘱!

不良反应
常见腹部绞痛或胀气、恶心、足水肿、乳房胀痛、体重增加或减少等,罕见不规则阴道出血、突破性出血、困倦、尿频、头痛、不自主的急动作、腓肠肌痛、呼吸急促、突然语言不清、视力突然改变、乳腺出现小肿块、精神抑郁、肝炎及皮疹等。

注意事项
妊娠X类。长期或大量使用雌激素者,当停药或减量时须逐步减量。孕妇和哺乳期妇女禁用,已知或怀疑患有乳腺癌(晚期转移性乳腺癌例外)、雌激素依赖肿瘤及急性血栓性静脉炎或血栓栓塞者也禁用。心、肝、肾功能不全及哮喘、糖尿病、高血压、脑血管疾病、甲状腺疾病等慎用。

药物相互作用
可增加钙剂的吸收、降低他莫昔芬的治疗效果,并可减低抗高血压药的作用和增强抗抑郁药的不良反应。与抗凝药同用时,雌激素可降低抗凝效应,应调整抗凝药剂量。

Drug Uses
Estrace is used in the treatment of conditions caused by menopause. It is also used in the treatment of vaginal atrophy and preventing osteoporosis in women.

Usage
Take exactly as prescribed by your doctor. You may take it with a meal to avoid an upset stomach.

Missed Dose
You should try and take your doses on time taking care not to miss any. But if you do miss a dose, then you may take it immediately and space out the remaining doses. You may also skip it and continue with your regular dose. But do not take a double dose to compensate for the missed dose.

Storage
Store it at room temperature away from direct light, heat and moisture. Keep away from children.

Overdose
Excessive vaginal bleeding, severe nausea, and vomiting are some of the typical symptoms of an overdose. Seek medical attention immediately if you suspect an overdose.

More Information
The drug may cause light-headedness, dizziness, and faintness in some people. Do not consume alcohol along with the drug. Do not drive or handle heavy machinery until you know how to react to the drug. Use only if prescribed.

Warnings/Precautions
Do not use Estrace if:
you are allergic to any ingredient in Estrace;
you are pregnant or suspect you may be pregnant, have recently given birth or are breast-feeding, or have vaginal bleeding of abnormal or unknown cause;
you have known or suspected breast cancer (unless directed by your doctor) or you have cancers that are estrogen-dependent;
you have blood clots, vein inflammation, or liver disease;
you have had a recent stroke or heart attack.
Contact your doctor or health care provider right away if any of these apply to you.

Important:
Estrace may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use Estrace with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
Limit alcoholic beverages while you are taking Estrace.
Estrace may cause dark skin patches on your face (melasma). Exposure to the sun may make these patches darker and you may need to avoid prolonged sun exposure and sunlamps. Consult your doctor regarding the use of sunscreens and protective clothing.
Estrace may increase the risk of blood clots. The risk may be greater if you smoke (especially in women older than 35 years of age).
Contact your doctor if vaginal bleeding of unknown cause occurs. This could be a sign of a serious condition requiring immediate medical attention.
Contact your doctor if vaginal discomfort occurs or if you suspect you have developed an infection while taking Estrace.
Follow your doctor's instructions for examining your breasts and report any lumps immediately.
Additional monitoring of your dose or condition may be necessary if you are presently taking an azole antifungal (e.g., itraconazole), carbamazepine, a macrolide antibiotic (e.g., erythromycin), ritonavir, cimetidine, or St. John's wort.
If you will be having surgery or will be confined to a chair or bed for a long period of time (e.g., a long plane flight), notify your doctor beforehand. Special precautions may need to be taken in these circumstances while you are taking Estrace.
Nonprescription therapy to help prevent bone loss includes a weight-bearing exercise plan, as well as adequate daily calcium and vitamin D intake. Consult your doctor or pharmacist for more details.
Estrace may interfere with certain lab tests. Be sure your doctor and lab personnel know you are taking Estrace.
Diabetes patients - Estrace may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
Lab tests, including physical exams and blood pressure, may be performed while you use Estrace . You should have breast and pelvic exams, and a Pap test at least once a year. You should also have periodic mammograms as determined by your doctor. Be sure to keep all doctor and lab appointments.
Pregnancy and breast-feeding: Do not use Estrace if you are pregnant. Avoid becoming pregnant while you are taking it. If you think you may be pregnant, contact your doctor right away. Estrace may be found in breast milk. If you are or will be breast-feeding while you use Estrace, check with your doctor. Discuss any possible risks to your baby.

Possible Side Effects
Check with your doctor if any of these most common side effects persist or become bothersome:

breast pain or tenderness; headache; hair loss; mild nausea or vomiting; spotting or breakthrough bleeding; stomach cramps or bloating.
Seek medical attention right away if any of these severe side effects occur:

severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); back pain;breast discharge or lump in the breast; calf or leg pain or swelling; chest pain; coughing up blood; dark urine; depression; dizziness; fainting; fever; memory problems; mental or mood changes; muscle pain; one-sided weakness; painful or difficult urination; persistent or severe breast pain or tenderness; persistent or severe headache, nausea, or vomiting; severe stomach pain or swelling; slurred speech; sudden shortness of breath; sunburn-like rash; swelling of hands, legs, or feet; unusual vaginal bleeding, discharge, itching, or odor; vision changes; vomiting; weakness or numbness of an arm or leg; yellowing of the skin or eyes.

More Information
If you have any questions about Estrace, please talk with your doctor, pharmacist, or other health care provider.
Estrace is to be used only by the patient for whom it is prescribed. Do not share it with other people.

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 详细处方信息以本药内容附件PDF文件(20127919435826.PDF,20127919435311.PDF)的“原文Priscribing Information”为准
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更新日期: 2012-7-10
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