药品信息:
--------------------------------------------------------------- 详细处方信息以本药内容附件PDF文件(201232118491430.PDF,201232118490522.PDF)的“原文Priscribing Information”为准 --------------------------------------------------------------- 部分中文CoPlavix处方资料(仅供参考)
Clopidogrel,中文名叫:氯吡格雷。 是个抗血凝的药物。 血小板的凝聚,最后就会造成血液凝结,形成血栓。 怎么形成这个抗血凝聚的作用呢?就是氯吡格雷会阻断腺苷二磷酸和血小板的结合,因此阻止血栓的产生。
Aspirin:阿司匹林是一种非甾体抗炎药,也叫乙酰水杨酸,可以解热镇痛,抗炎抗风湿治疗痛风,还可以抗血栓,现在已被广泛应用于心血管疾病的一级预防和二级预防。
CoPlavix - Concise Prescribing Information Manufacturer:sanofi-aventis
Distributor:Zuellig
Contents:Clopidogrel 75 mg, acetylsalicylic acid 100 mg
Indications:Prevention of atherothrombotic events in patients suffering from non-ST segment elevation acute coronary syndrome (unstable angina/non-Q-wave MI); ST segment elevation acute MI in medically treated patients eligible for thrombolytic therapy.
Dosage:Adult & elderly 1 tab as single daily dose. Non-ST segment elevation acute coronary syndrome (unstable angina/non-Q-wave MI) Initially 300 mg as single dose of clopidogrel & an appropriate dose of ASA, then CoPlavix 1 tab once daily for 12 mth. ST segment elevation acute MI Therapy should be started as soon as symptoms start, then continued for at least 4 wk.
Overdosage:View CoPlavix overdosage for action to be taken in the event of an overdose.
Administration:May be taken with or without food (May be taken w/ meals to reduce GI discomfort.).
Contraindications:Severe renal & hepatic impairment, active pathological bleeding eg peptic ulcer/intracranial haemorrhage; allergy to NSAID, patients w/ asthma, rhinitis & nasal polyps; history of peptic ulcer, haemophilia & other bleeding disorders. Galactose intolerance, Lapp lactase deficiency/glucose-galactose malabsorption.
Special Precautions:Monitor blood cell count. Patient at risk of increased bleeding from trauma, surgery or other pathological conditions. Discontinue use 7 days prior to surgery. Lesions w/ a propensity to bleed. Recent transient ischaemic attack or stroke. Mild to moderate renal impairment. Moderate hepatic disease. Asthma or allergic disorders, gout, HTN; history of peptic ulcer/gastroduodenal hemorrhage/minor upper GI symptoms. Pregnancy & lactation. Childn.
Adverse Drug Reactions:GI bleeding, purpura/bruising & epistaxis. Severe neutropenia & thrombocytopenia. Diarrhoea, abdominal pain & dyspepsia. View ADR Monitoring Form
Drug Interactions:Oral anticoagulants, glycoprotein IIb/IIIa inhibitors, heparin, thrombolytics, NSAIDs, uricosurics, methotrexate, ACE inhibitors, acetazolamide, anticonvulsants, β-blockers, diuretics & oral hypoglycemic agents. View more drug interactions with CoPlavix
Storage:View CoPlavix storage conditions for details to ensure optimal shelf-life.
Description:View CoPlavix description for details of the chemical structure and excipients (inactive components).
Mechanism of Action:View CoPlavix mechanism of action for pharmacodynamics and pharmacokinetics details.
MIMS Class:Anticoagulants, Antiplatelets & Fibrinolytics (Thrombolytics)
ATC Classification:B01AC04 - clopidogrel ; Belongs to the class of platelet aggregation inhibitors excluding heparin. Used in the treatment of thrombosis.
Poison Schedule:POM
--------------------------------------------------------------- 详细处方信息以本药内容附件PDF文件(201232118491430.PDF,201232118490522.PDF)的“原文Priscribing Information”为准 --------------------------------------------------------------- |