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 详细处方信息以本药内容附件PDF文件（201122323313611.pdf）的“原文Priscribing Information”为准
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部分中文依酚氯铵处方资料（仅供参考）

中文名称：依酚氯铵

中文别名：氯化艾卓酚; N-乙基-3-羟基-N,N-二甲基苯胺氯化物
 
英文名称：edrophonium chloride

英文别名：N-ethyl-3-hydroxy-N,N-dimethylanilinium chloride; ethyl(3-hydroxyphenyl)dimethylammonium chloride

分类名称：
一级分类：神经系统药物 二级分类：神经细胞活化剂及营养药物 三级分类：胆碱酯酶抑制剂 
 
药品英文名：Edrophonium Chloride
 
药品别名：腾喜龙、艾宙酚、Tensilon、Enlon、Enlon-Plus、Reversol、Camsilon
 
药物剂型：注射剂
 
药理作用：属季铵类易逆性抗胆碱酯酶药。作用同新斯的明。
 
药动学：对骨骼肌的兴奋作用强大，作用快速而短暂。注射后30～60秒即可出现作用，维持时间10分钟左右。Vd为1.1士0.2L/kg，t1/2为1.8土0.6小时。 
 
适应证：
(1)作为重症肌无力诊断剂：重症肌无力病人用药后，症状迅速改善，肌强度增加，作用维持5～15分钟后，恢复至原先的症状与体征。采用步骤为：静脉注射2mg，30～45秒内无不良反应，继续注射8mg。英国推荐儿童用药总量100μg/kg。开始采用剂量的1/5，若无不良反应，再给以余量。美国建议儿童用量：体重在34kg以下者，总量5mg，体重较重者为10mg。开始用剂量的1/5，每隔30～45秒增加1mg。静脉给药困难时可采用肌内注射，成人剂量10mg；儿童体重34kg以下用量2mg，体重较重者5mg。进行试验时，必须备有阿托品，以便及时处理严重的M胆碱受体兴奋症状。
(2)鉴别诊断重症肌无力用药过量或用量不足：用量不足者，用依酚氯铵后可使症状很快改善；若肌力下降，表踢抗胆碱酯酶药用药过量。
(3)解救非去极化型肌肉松弛药过量。
 
禁忌证：有肠或尿道梗阻者禁用，患支气管哮喘及心脏病者慎用。 
 
不良反应：流涎、恶心、呕吐、腹痛、腹泻、尿频、支气管痉挛、心动过缓、心律失常等。

Brand Names: Enlon, Tensilon

Generic Name: edrophonium (Pronunciation: ED roe FOE nee um)

What is edrophonium (Enlon, Tensilon)?
Edrophonium is used as part of a medical test to help diagnose a muscle disorder called myasthenia gravis.

Edrophonium is sometimes used to reverse the effects of certain medications used to prevent muscle contractions during surgical procedures.

Edrophonium may also be used for other purposes not listed in this medication guide.

What are the possible side effects of edrophonium (Enlon, Tensilon)?
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Tell your caregivers at once if you have a serious side effect such as:
slow heart rate;
chest pain, weak pulse, increased sweating, and dizziness;
feeling like you might pass out;
weak or shallow breathing;
urinating more than usual;
seizures (convulsions); or
trouble swallowing.

Less serious side effects (some of which can be expected as part of a positive test reaction) may include:
watery eyes, vision problems;
changes in your voice;
mild nausea, vomiting, diarrhea, stomach pain;
weakness; or
muscle twitching.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about edrophonium (Enlon, Tensilon)?
You should not receive this medication if you are allergic to edrophonium, or have a blockage in your intestines or obstructed urine flow.

Before you receive edrophonium, tell your doctor if you have asthma, a heart rhythm disorder, or if you are allergic to sulfites. Also tell your doctor if you are pregnant or breast-feeding.

Tell your caregivers at once if you have a serious side effect such as slow heart rate, chest pain, weak pulse, fainting, weak or shallow breathing, increased urination, seizures, or trouble swallowing.

Less serious side effects may occur (some of which can be expected as part of a positive test reaction to edrophonium) such as watery eyes, vision problems, changes in your voice, mild nausea, vomiting, stomach pain, weakness, or muscle twitching.

What should I discuss with my health care provider before receiving edrophonium (Enlon, Tensilon)?
You should not receive this medication if you are allergic to edrophonium, or have certain conditions. Be sure your doctor knows if you have:
a blockage in your intestines; or
obstructed urine flow.

Before you receive edrophonium, tell your doctor if you are allergic to any drugs, or if you have:
asthma;
a heart rhythm disorder; or
if you are allergic to sulfites.
If you have any of these conditions, you may need a dose adjustment or special tests to safely receive edrophonium.

This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant before you receive edrophonium.

Do not receive this medication without telling your doctor if you are breast-feeding a baby.

How is edrophonium given (Enlon, Tensilon)?
Edrophonium is given as an injection through a needle placed into a muscle or vein. You will receive this injection in a clinic or hospital setting as part of a medical test.

When used in diagnosing myasthenia gravis, edrophonium is given in small doses over 15 to 45 seconds. After each dose you will be observed for the expected reaction to this medication (muscle twitching, vision changes, increased muscle weakness, sweating, stomach cramps, nausea, and other symptoms). You may receive other medications to treat the reaction to edrophonium.

The test you are receiving may be repeated a second time.

Your specific edrophonium test may be performed in a different manner than described above.

What happens if I miss a dose (Enlon, Tensilon)?
Since edrophonium is given by a healthcare professional, it is not likely that you will miss a dose.

What happens if I overdose (Enlon, Tensilon)?
Tell your caregivers right away if you think you have received too much of this medicine.

Overdose symptoms may include nausea, vomiting, diarrhea, sweating, slow heart rate, and increased salivation (drooling).

What should I avoid after receiving edrophonium (Enlon, Tensilon)?
Follow your doctor's instructions about any restrictions on food, beverages, or activity after you have been treated with edrophonium.

What other drugs will affect edrophonium (Enlon, Tensilon)?
There may be other drugs that can interact with edrophonium. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

Where can I get more information?
Your doctor or pharmacist can provide more information about edrophonium.

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 详细处方信息以本药内容附件PDF文件（201122323313611.pdf）的“原文Priscribing Information”为准
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