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  药店国别: 美国药房
产地国家: 美国
所属类别: 神经系统药物->广泛性焦虑症
处方药:处方药
包装规格: 10毫克/片 30片/盒
计价单位:
  点击放大  
该药品相关信息网址1:
http://www.wellbutrin.com/
该药品相关信息网址2:
http://http://www.rxlist.com/wellbutrin-sr-drug.htm
该药品相关信息网址3:
http://baike.baidu.com/view/1732883.htm?fr=ala0
原产地英文商品名:
BUSPIRONE HCL(WELLBUTRIN GENERIC) 10MG/TAB 30TABS/BOX
原产地英文药品名:
BUSPIRONE HCL
中文参考商品译名:
盐酸丁螺环酮(WELLBUTRIN仿制药) 10毫克/片 30片/盒
中文参考药品译名:
盐酸丁螺环酮
原产地国家批准上市年份:
0000/00/00
英文适应病症1:
Anxiolytic
临床试验期:
完成
中文适应病症参考翻译1:
抗焦虑
药品信息:

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详细处方信息以本药内容附件PDF文件(201133019284423.pdf)的“原文Priscribing Information”为准
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部分中文丁螺环酮 处方信息(仅供参考)

What is WELLBUTRIN SR?
WELLBUTRIN SR is a prescription medicine used to treat adults with a certain type of depressioncalled major depressive disorder.

Who should not take WELLBUTRIN SR?
Do not take WELLBUTRIN SR if you
• have or had a seizure disorder or epilepsy.
• are taking ZYBAN® (used to help people stop smoking) or any other medicines that contain
bupropion hydrochloride, such as WELLBUTRIN® Tablets or WELLBUTRIN XL® Extended-Release Tablets. Bupropion is the same active ingredient that is in WELLBUTRIN SR.
• drink a lot of alcohol and abruptly stop drinking, or use medicines called sedatives (these
make you sleepy) or benzodiazepines and you stop using them all of a sudden.
• have taken within the last 14 days medicine for depression called a monoamine oxidase
inhibitor (MAOI), such as NARDIL®*(phenelzine sulfate), PARNATE®(tranylcypromine sulfate), or MARPLAN®*(isocarboxazid).
• have or had an eating disorder such as anorexia nervosa or bulimia.
• are allergic to the active ingredient in WELLBUTRIN SR, bupropion, or to any of the inactive
ingredients. See the end of this leaflet for a complete list of ingredients in WELLBUTRIN SR.

What should I tell my doctor before using WELLBUTRIN SR?
Tell your doctor if you have ever had depression, suicidal thoughts or actions, or other mental
health problems. See “Antidepressant Medicines, Depression and Other Serious Mental Illnesses, and Suicidal Thoughts or Actions.”
• Tell your doctor about your other medical conditions including if you:
• are pregnant or plan to become pregnant. It is not known if WELLBUTRIN SR can harm your unborn
baby.
• are breastfeeding. WELLBUTRIN SR passes through your milk. It is not known if WELLBUTRIN SR
can harm your baby.
• have liver problems, especially cirrhosis of the liver.
• have kidney problems.
• have an eating disorder such as anorexia nervosa or bulimia.
• have had a head injury.
• have had a seizure (convulsion, fit).
• have a tumor in your nervous system (brain or spine).
• have had a heart attack, heart problems, or high blood pressure.
• are a diabetic taking insulin or other medicines to control your blood sugar.
• drink a lot of alcohol.
• abuse prescription medicines or street drugs.
• Tell your doctor about all the medicines you take, including prescription and non-prescription
medicines, vitamins, and herbal supplements. Many medicines increase your chances of having seizures or other serious side effects if you take them while you are using WELLBUTRIN SR.

How should I take WELLBUTRIN SR?
• Take WELLBUTRIN SR exactly as prescribed by your doctor.
• Do not chew, cut, or crush WELLBUTRIN SR Tablets. You must swallow the tablets whole. Tell
your doctor if you cannot swallow medicine tablets.
• Take WELLBUTRIN SR at the same time each day.
• Take your doses of WELLBUTRIN SR at least 8 hours apart.
• You may take WELLBUTRIN SR with or without food.
• If you miss a dose, do not take an extra tablet to make up for the dose you forgot. Wait and
take your next tablet at the regular time. This is very important. Too much WELLBUTRIN SR can increase your chance of having a seizure.
• If you take too much WELLBUTRIN SR, or overdose, call your local emergency room or poison
control center right away.
• Do not take any other medicines while using WELLBUTRIN SR unless your doctor has told you it
is okay.
• It may take several weeks for you to feel that WELLBUTRIN SR is working. Once you feel better,
it is important to keep taking WELLBUTRIN SR exactly as directed by your doctor. Call your doctor if you do not feel WELLBUTRIN SR is working for you.
• Do not change your dose or stop taking WELLBUTRIN SR without talking with your doctor first.

What should I avoid while taking WELLBUTRIN SR?
• Do not drink a lot of alcohol while taking WELLBUTRIN SR. If you usually drink a lot of
alcohol, talk with your doctor before suddenly stopping. If you suddenly stop drinking alcohol, you may increase your chance of having seizures.
• Do not drive a car or use heavy machinery until you know how WELLBUTRIN SR affects you.
WELLBUTRIN SR can impair your ability to perform these tasks.

What are possible side effects of WELLBUTRIN SR?
WELLBUTRIN SR can cause serious side effects. Read this entire Medication Guide for more
information about these serious side effects.
The most common side effects of WELLBUTRIN SR are loss of appetite, dry mouth, skin rash,
sweating, ringing in the ears, shakiness, stomach pain, agitation, anxiety, dizziness, trouble sleeping, muscle pain, nausea, fast heartbeat, sore throat, and urinating more often.
If you have nausea, take your medicine with food. If you have trouble sleeping, do not take your
medicine too close to bedtime.
These are not all the side effects of WELLBUTRIN SR. For a complete list, ask your doctor or
pharmacist.Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

How should I store WELLBUTRIN SR?
• Store WELLBUTRIN SR at room temperature. Store out of direct sunlight. Keep WELLBUTRIN SR in
its tightly closed bottle.
• WELLBUTRIN SR tablets may have an odor.

丁螺环酮 Buspirone

中文别名:丁螺环酮、布斯帕、布斯哌隆、丁螺旋酮、希司必隆

药品种别: 抗焦炙药

药物医理药动
  本品结构与其他抗焦炙药不同,动物实验显示丁螺环酮对中枢的去甲肾上腺素、胆碱能、组胺、阿片等受体均无较着作用,亦不作用于苯二氮卓类受体,不影响GABA 对苯二氮卓类的作用。本品作用于海马部位5-HT1A受体及多巴胺受体。前者使5-HT 功能向下调节,孕育发生抗焦炙作用,对DA受体有亲切感,阻断突触前膜 DA受体。对突触后膜受体的作用如何,今朝有许多相矛盾的发现。有人认为它既是 DA冲动剂又是 DA拮抗剂,但因为对 DA受体作用较弱,故临床上副反应很轻。这个之外,它能减低 5-HT2受体敏感性,故又有抗抑郁作用。

药动学
  口服吸收好,达峰时间为0.5~1h,血浆蛋白联合率为 95%。大部门在肝脏代谢、主要代谢物为 5羟基丁螺环酮以及 1-(2-嘧啶基)药名。半减期为 2~11h,血透不能消除体内丁螺环酮,60%由尿排出,40%从屎尿排出。

适应症
  丁螺环酮有较着抗焦炙作用,适用于各型焦炙状态。不孕育发生较着的镇静作用,亦不与其他安眠药孕育发生协同作用,亦不加强乙醇的作用。不能消除成瘾药的戒断反应,本身也不孕育发生戒断反应。对焦炙伴严重掉眠者,尚需加用快作用安眠药。上海市精神卫生中心临床双盲 30例试验报告,有效率为 70%。

用法用量
  口服每一日 3次,每一次 5mg,以后可增至每一日 20~30mg,老年人一般每一日不宜超过 15mg。
  [剂型与规格]片剂:5mg/片,10mg/片。
  [用法]口服:开始剂量为每一日 10mg,以后每一 2—3日增加 1次剂量。一般有效剂量为每一日 20— 30mg。如果每一日用至 40mg仍无效时,有可能再加量亦无效,不该再用。显效时间在用药 2周左右,少数患者还可更长,故在达到最大剂量后尚需接续治疗 2—3周,勿匆忙换药。

不良反应
  以肠胃道不适为多见,这个之外,尚有头晕、头痛、冲动、掉眠等。

禁忌症
  严重肝、肾功能不全、青光眼及重症肌无力患者禁用。

药物相互作用
  不宜与乙醇、中枢按捺药、降压药、降糖药、抗凝药、避孕药及MAOI合用。

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详细处方信息以本药内容附件PDF文件(201133019284423.pdf)的“原文Priscribing Information”为准
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更新日期: 2012-3-27
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